Peptide Tools to Study SARS-CoV-2

JPT's Peptide Tools to Study SARS-CoV-2

JPT has launched a broad development program to provide access to genome spanning SARS-CoV-2 peptide tools and its different mutation variants for applications such as:

  • SARS-CoV-2 clinical trial immune monitoring
  • SARS-CoV-2 evaluation of cross reactivities
  • SARS-CoV-2 blood and sero test development
  • SARS-CoV-2 T-and B-cell epitope discovery

We have broadened our portfolio of coronavirus related products beyond SARS-CoV-2, including SARS-CoVMERS-CoV and common cold viruses CoV 229E, OC43, HKU1 and NL63. Have a look below!

About SARS-CoV-2

SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), the causative agent of Covid-19, is responsible for the current pandemic. Developing and monitoring vaccines, therapies and diagnostic tests that are safe, effective, and rapidly deployable is an urgent global health priority.
Check our SARS-CoV-2 Flyer



WHO Designation 
Variant of Concern 202012/01
Alternative names
Lineage B.1.1.7, UK variant, British variant, Kent variant, Alpha

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WHO Designation
Variant of Concern
Alternative names
501Y.V2 variant, 20H/501Y.V2, 20C/501Y.V2, B.1.351 lineage, South African variant, Beta

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WHO Designation
Variant of Concern
Alternative names
B.1.617.2 lineage, G/478K.V1, 20A/S:478K, Indian Variant, Delta

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WHO Designation
Formerly Monitored Variant
Alternative names
B.1.429 lineage, CAL.20C, Los Angeles Variant, Epsilon

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WHO Designation
Variant of Concern
Alternative names
P.1, B.1.1.248, B., 20J/501Y.V3, Brazil(ian) variant, Gamma

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WHO Designation
Formerly Monitored Variant

Alternative names
B.1.617.1 lineage, G/452R.V3, Indian Variant, Kappa
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WHO Designation 
Variant of Interest
C.37 lineage
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Omicron BA.1

Omicron BA.1

WHO Designation
Variant of Concern

B.1.1.529 lineage (BA.1)
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Omicron BA.2

Omicron BA.2

WHO Designation
Variant of Concern

B.1.1.529 lineage (BA.2)
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Omicron BA.4/5

Omicron BA.4/5

WHO Designation 
Variant of Concern 

B.1.1.529 lineage (BA.4/5)
More Information

Spike Mutations in SARS-CoV-2 Variants of Concern covered by PepMix™

see Overview Table

Peptide Tools to Study SARS-CoV-2

Cellular Immunity
-> PepMix™ Peptide Pools
  • Antigen-specific T-cell stimulation
  • Cellular immune monitoring
  • Vaccine target discovery
  • Blood test development
  • Cross reactivity testing (SARS-CoV-2 vs. SARS, MERS, HCoV 229E, OC43…)
  • Cell therapy development
  • Efficient epitope mapping and identification
  • Matrix Pools and individual peptides spanning a whole antigen in one set
  • Minimal sample amount required
  • Antigen specific T-cell stimulation in T-cell assays (i.e. ELISpot, ICS)
  • Immune monitoring
  • Proliferation assays
  • T-cell expansion
Humoral Immunity
-> PepStar™ Peptide Microarrays
  • Humoral immune monitoring
  • Antibody epitope discovery
  • Cross reactivity testing (SARS-CoV-2 vs. SARS, MERS, HCoV 229E, OC43…)
  • Seromarker discovery
PepStar™ Antigen Collection Pan-Coronavirus
for cross reactivity testing with SARS-CoV-2 vs. SARS, MERS, HCoV 229E, OC43…)
PepStar™ Peptide Microarrays
for individual SARS-CoV-2 and SARS-CoV antigens
Tailored PepStar™ Peptide Microarrays
You define content and layout, we provide economic and fast production in our regulated clean-room environment. We also offer our assay and analysis service using your samples with your tailored peptide microarray.

  • Thousands of peptides spanning the entire SARS-CoV-2 genome using smallest sample volumes
  • Incubation using smallest sample volumes
  • Study of antibody cross-reactivities between SARS-CoV-2 and other corona viruses
  • Verification of peptide binders with a large numbers of samples
  • Transfer of results to ELISA platform for rapid test development
  • Peptide ELISA development and service using SARS-CoV-2 peptides or a combination with other corona viruses
  • ELISA-based validation service of peptide binders identified by using JPT’s peptide microarray platform
  • Collaborative ELISA test development
Clinical Immune Monitoring & Cell Therapy
-> Clinical Grade Peptides & PepMix™ Peptide Pools
  • High quality chemically synthesized antigen source for vaccine trial monitoring
  • Ancillary reagents for cellular therapy development
  • Full analytical coverage, stability testing, batch documentation and more
-> SpikeMix™ SARS-CoV-2
  • Identify SARS CoV-2 antigens from biological samples
  • Mass spectrometry based assays (MRM)
  • Screen 23 proteotypic peptides from SARS-CoV-2



  • Analysis of the humoral and cellular response after the third COVID-19 vaccination in patients with autoimmune hepatitis
    Hartl et al., Liver International (2022) - PMID: 35840342
  • Respiratory mucosal immunity against SARS-CoV-2 following mRNA vaccination
    Tang et al., Science Immunology (2022) - PMID: 35857583
  • Robust SARS-COV-2-specific T-cell immune memory persists long-term in immunocompetent individuals post BNT162b2 double shot
    Papadopoulou et al., Heliyon (2022) - PMID: 35815135
    Product used: PepMix SARS-CoV-2 (Spike Glycoprotein) 
  • A novel SARS-CoV-2 subunit vaccine engineered on an immune-activating platform technology
    Quinlan et al., Human Vaccines & Immunotherapeutics (2022) - PMID: 35801956
    Product used: PepMix SARS-CoV-2 (Spike-RBD) 
  • Safety and immunogenicity of intramuscular, single- dose V590 (rVSV-SARS-CoV-2 Vaccine) in healthy adults: Results from a phase 1 randomised, double- blind, placebo-controlled, dose-ranging trial
    Robbins et al., The Lancet (2022)
    Product used: PepMix SARS-CoV-2 (Spike Glycoprotein) 
  • Longitudinal T Cell Responses against Ancestral, Delta, and Omicron SARS-CoV-2 Variants determined by Rapid Cytokine Release Assay in Whole Blood
    Oliver et al., Immunohorizons (2022) - PMID: 35750357
    Products used: PepMix SARS-CoV-2 (Spike Glycoprotein SU1 & SU2), SARS-CoV-2 (Spike B.1.617/Delta),  SARS-CoV-2 (Spike B.1.1.529 / BA.1 / Omicron)
  • Long-Lived Immunity in SARS-CoV-2-Recovered Children and Its Neutralizing Capacity Against Omicron
    Sieber et al., Frontiers in Immunology (2022) - PMID: 35663948
    Product used: PepMix SARS-CoV-2 (VME1), SARS-CoV-2 (VEMP), SARS-CoV-2 (NCAP),  SARS-CoV-2 (Spike B.1.1.529 / BA.1 / Omicron) 
  • T-cell proliferation assay for the detection of SARS-CoV-2-specific T-cells
    Chu et al., Clinical Chimica Acta (2022) - PMID: 35690083
    Products used: PepMix SARS-CoV-2 (Spike Glycoprotein), SARS-CoV-2 (NCAP), SARS-CoV-2 (VME1) 
  • A DNA vaccine candidate delivered by an electroacupuncture machine provides protective immunity against SARS-CoV-2 infection
    Tzeng et al., Vaccines (2022) 
  • Chimeric Virus-like Particle-Based COVID-19 Vaccine Confers Strong Protection against SARS-CoV-2 Viremia in K18-hACE2 Mice
    Kaewborisuth et al., Vaccines (2022) 
  • SARS-CoV-2 OmicronBA.1 variant breakthrough infections in nursing home residentsafter an homologousthird dose of the Comirnaty® COVID-19 vaccine: Looking for correlates of protection
    Torres et al., Journal of Medical Virology (2022) 
    Products used: PepMix™ SARS-CoV-2 (Spike Glycoprotein SUB1 & SUB2)
  • Functional Analysis of Human and Feline Coronavirus Cross-Reactive Antibodies Directed Against the SARS-CoV-2 Fusion Peptide
    Vanderheijden et al., Frontiers in Immunology (2022) - PMID: 35069571
  • Durable immunogenicity, adaptation to emerging variants and low dose efficacy of AAV-based COVID19 platform in macaques
    Zabaleta et al., Molecular Therapy (2022)
    Products used: PepMix™ SARS-CoV-2 (Spike Glycoprotein SUB1 & SUB2)
  • Enhanced Humoral Immune Response After COVID-19 Vaccination in Elderly Kidney Transplant Recipients on Everolimus Versus Mycophenolate Mofetil–containing Immunosuppressive Regimens
    de Boer et al., Translantation (2022) - PMID: 35546527
    Products used: PepMix™ SARS-CoV-2 (Spike Glycoprotein SUB1 & SUB2)
  • SARS-CoV2 wild type and mutant specific humoral and T cell immunity is superior after vaccination than after natural infection
    Richardson et al., PLoS One (2022) - PMID: 35468147
    Products used: PepMix™ SARS-CoV-2 (Spike Glycoprotein), SARS-CoV-2 (Spike B.1.1.7 / Alpha), SARS-CoV-2 (Spike B.1.351 / Beta), SARS-CoV-2 (Spike P.1 / Gamma), SARS-CoV-2 (Spike B.1.617.2 / Delta)
  • Two DNA vaccines protect against severe disease and pathology due to SARS-CoV-2 in Syrian hamsters
    Babuadze et al., NPJ Vaccines (2022) - PMID: 35474311
    Product used: PepMix™ SARS-CoV (Spike Glycoprotein)
  • Transcriptomic analysis reveals optimal cytokine combinations for SARS-CoV-2 Specific T cell therapy products
    Durkee-Shock et al., Molecular Therapy: Methods & Clinical Development (2022)
  • Longitudinal T-Cell Responses After a Third SARS-CoV-2 Vaccination in Patients With Multiple Sclerosis on Ocrelizumab or Fingolimod
    Cabeza et al., Neurology: Neuroimmunology & Neuroinflammation - PMID: 35523569
    Products used: PepMix™ SARS-CoV-2 (Spike Glycoprotein SUB1 & SUB2)
  • Children and Adults With Mild COVID-19: Dynamics of the Memory T Cell Response up to 10 Months
    Kaaijk et al., Frontiers in Immunology (2022)
    Products used: PepMix™ SARS-CoV-2 (Spike Glycoprotein), SARS-CoV-2 (NCAP), HCoV-OC43 (Spike Glycoprotein)
  • Strong peak immunogenicity but rapid antibody waning following third vaccine dose in elderly residents of care homes
    Tut et al., Research Square (2022)
    Product used: PepMix™ SARS-CoV-2 (Spike Glycoprotein)
  • Discordant antibody and T cell responses to the SARS-CoV-2 Omicron variant in COVID-19 mRNA vaccine recipient
    Woldemeskel et al., Clinical Infectious Diseases (2022) - PMID: 35438751
    Products used: PepMix™ SARS-CoV-2 (Spike Glycoprotein) & SARS-CoV-2 (S-RBD B.1.1.529 / Omicron)
  • USA SARS-CoV-2 Epsilon Variant: Though Highly Transmissible has an Adjusted Muted Host T-Cell Response
    Plummer et al., Clinical Infectious Diseases (2022) - PMID: 35438777
    Products used: PepMix™ SARS-CoV-2 (Spike Glycoprotein) & SARS-CoV-2 (Spike B.1.429 / Epsilon)
  • mRNA booster vaccination protects extremely aged mice against the SARS-CoV-2 Omicron variant
    Dowling et al., Research Square (2022)
    Products used: PepMix™ SARS-CoV-2 (Spike Glycoprotein) & SARS-CoV-2 (S-RBD B.1.1.529 / Omicron)
  • Viral Evolution and Immunology of SARS-CoV-2 in a Persistent Infection after Treatment with Rituximab
    van der Moerden et al., Viruses (2022)
  • Dynamics of SARS-CoV-2-Spike-reactive antibody and T-cell responses in chronic kidney disease patients within three months after COVID-19 full vaccination
    Panizo et al., Clinical Kidney Journal (2022)
    Product used: PepMix™ SARS-CoV-2 (Spike Glycoprotein)
  • Safety and immunogenicity of a reduced dose of the BNT162b2 mRNA COVID-19 vaccine (REDU-VAC): a single blind, randomized, non-inferiority trial
    Pannus et al., MedRxiv (2022)
  • Temporal changes in T cell subsets and expansion of cytotoxic CD4+ T cells in the lungs in severe COVID-19
    Kaneko et al., Clinical Immunology (2022) - PMID: 35364330
  • T cell response against SARS-CoV-2 persists after one year in patients surviving severe COVID-19
    Venet et al., EBioMedicine (2022) - PMID: 35349827
  • CD4+ T Cell Dysfunction in Severe COVID-19 Disease is TNFalpha/TNFRI-Dependent
    Popescu et al., American Journal of Respiratory Critical Care Medicine - PMID: 35348444
  • The Quality of Anti-SARS-CoV-2 T Cell Responses Predicts the Neutralizing Antibody Titer in Convalescent Plasma Donors
    Kroemer et al., Front Public Health (2022) - PMID: 35372242
  • High antibody and reduced cellular response in children up to one year after SARS-CoV-2 infection
    Jacobsen et al., Research Square (2022)
  • Immune responses against SARS-CoV-2 variants after two and three doses of vaccine in B-cell malignancies: UK PROSECO study
    Lim et al., Nature Cancer (2022) - PMID : 35332334
  • Self-amplifying mRNA SARS-CoV-2 vaccines raise cross-reactive immune response to variants and prevent infection in animal models
    Palladino et al., Methods and Clinical Development (2022)
  • Evolution of Humoral and Cellular Immunity in Two COVID-19 Breakthrough Infections After BNT162b2 Vaccine
    Gallais et al., Frontiers in Immunology (2022) - PMID: 35281046
  • SARS‐CoV‐2 vaccination response in patients with autoimmune hepatitis and autoimmune cholestatic liver disease
    Duengelhoef et al., United European Gastroenterol Journal (2022) - PMID: 35289983
  • Novel T cell interferon gamma release assay (IGRA) using spike recombinant protein for COVID19 vaccine response and Nucleocapsid for SARS-Cov2 response
    Renaudineau et al., Clinical Immunology (2022) - PMID: n.a.
  • Immune response and safety of heterologous ChAdOx1-nCoV-19/mRNA-1273 vaccination compared with homologous ChAdOx1-nCoV-19 or homologous mRNA-1273 vaccination
    Sheng et al., Journal of the Formosan Medical Association (2022) - PMID: 35305895
  • Modular capsid decoration boosts adenovirus vaccine-induced humoral and cellular immunity against SARS-CoV-2
    Dicks et al., BioRxiv (2022)
  • SARS-CoV- 2 (COVID- 19)-specific T cell and B cell responses in convalescent rheumatoid arthritis: Monozygotic twins pair case observation
    Arruda et al., Immunology (2022) - PMID: 35212005
    Products used: PepMix™ SARS-CoV-2 (NCAP) & SARS-CoV-2 (Spike Glycoprotein)
  • Humoral and Cellular Immune Responses of Solid Organ Transplant Patients on Belatacept to Three Doses of mRNA-Based Anti-SARS-CoV-2 Vaccine
    Abravanel et al., Vaccines (2022)
    Products used: PepMix™ SARS-CoV-2 (Spike Glycoprotein)
  • Three-month follow-up of heterologous vs homologous third vaccination in kidney transplant recipients
    Heinzel et al., MedRxiv (2022)
  • Performance comparison of a fow cytometry immunoassay for intracellular cytokine staining and the QuantiFERON® SARS-CoV-2test for detection and quantifcation of SARS-CoV-2-Spike-reactiveIFN-γ-producing T cells after COVID-19 vaccination
    Tormo et al., European Journal of Clinical Microbiology & Infectious Diseases (2022) - PMID: 35165804
  • SARS-CoV-2-specific T cells generated for adoptive immunotherapy are capable of recognizing multiple SARS-CoV-2 variant
    Panikkar et al., Pathogens (2022) - PMID: 35157735
  • T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all prior infected and vaccinated individuals
    Vivek Naranbhai et al., MedRxiv (2022) - PMID: 35018386
  • Innate and adaptive immune defects associated with lower SARS-CoV-2 BNT162b2 mRNA vaccine response in elderly people
    Joana Vitallé et al., medRxiv (2022) - PMID: n.a.
  • Temporary hold of mycophenolate boosts SARS-CoV-2 vaccination-specific humoral and cellular immunity in kidney transplant recipients
    Eva Schrezenmeier et al., MedRxiv (2022) 
  • Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents
    Nina Koerber et al., Nature Communications (2022)
  • Persistent T-Cell Reactivity in a Seronegative Patient after SARS-CoV-2 Infection and One Vaccination
    Nico Andreas et al., Vaccines (2022)
  • Development of an effective immune response in adults with Down Syndrome 2 after SARS-CoV-2 vaccination
    Laura Esparcia-Pinedo et al., MedRxiv (2022) 
  • Antibody and T cell responses to SARS-CoV-2 mRNA vaccines during maintenance therapy for immune-mediated inflammatory diseases
    Dayam et al., MedRxiv (2022)
  • Infection or a third dose of mRNA vaccine elicit neutralizing antibody responses against SARS-CoV-2 in kidney transplant recipients
    Charmetant et al., Science Translational Medicine (2022) - PMID: 35103481
  • Concordance of B and T cell responses to SARS-CoV-2 infection, irrespective of symptoms suggestive of COVID-19
    Österdahl et al., MedRxiv (2022) 
  • Full efficacy and long-term immunogenicity induced by the SARS-CoV-2 vaccine candidate MVA-CoV2-S in mice
    Lázaro-Frías et al., Vaccines (2022)
  • mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits comparable B cell expansion, neutralizing antibodies and protection against Omicron
    Gagne et al., BioRxiv (2022)
  • Effectiveness and durability of the mRNA vaccine-induced SARSCoV-2-specific humoral and cellular immunity in severe asthma patients on biological therapy
    Prodrazil et al., MedRxiv (2022)
  • Limited Recognition of Highly Conserved Regions of SARS-CoV-2
    Swaminathan et al., Microbiology Spectrum (2022) - PMID: 35196796
  • Assessment of humora land cellular immune responses to SARSCoV-2 vaccination (BNT162b2) inimmunocompromised renal allograft recipients
    Zhang et al., Transplant Infectious Diseases (2022)
  • Tacrolimus-resistant SARS-CoV-2-specific T-cell products to prevent and treat severe COVID-19 in immunosuppressed patients
    Peter et al., Molecular Therapy (2022)
  • BNT162b2 Vaccine Induces Neutralizing Antibodies and Poly-Specific T Cells in Humans
    Ugur Sahin et al., Nature (2021)
  • Cross-Reactive CD4+ T Cells Enhance SARS-CoV-2 Immune Responses Upon Infection and Vaccination
    Loyal et al, Science (2021)
  • Protection Against SARS-CoV-2 Beta Variant in mRNA-1273 Vaccine–Boosted Nonhuman Primates
    Kizzmekia S. Corbett et al., Science, (2021)
  • Children Develop Strong and Sustained Cross-Reactive Immune Responses Against Spike Protein Following SARS-CoV-2 Infection, With Enhanced Recognition of Variants of Concern
    Alexander C. Dowell, medRxiv (2021)
  • Comorbid illnesses are associated with altered adaptive immune responses to SARS-CoV-2
    Krystle K.Q. Yu, JCI Insight (2021) - PMID: 33621211
  • Targeting SARS-CoV-2 Receptor-Binding Domain to Cells Expressing CD40 Improves Protection to Infection in Convalescent Macaques
    Romain Marlin, Nature Communications (2021)
  • Longitudinal Analysis of Human Memory T-Cell Response according to the Severity of Illness up to 8 Months after SARS-CoV-2 Infection
    Chang Kyung Kang, The Journal of Infectious Diseases (2021) - PMID: 33755725
  • Robust SARS-CoV-2-specific T cell immunity is maintained at 6 months following primary infection
    Jianmin Zuo, Nature (2021) - PMID: 33674800
  • SARS-CoV-2 Spike Protein Arrested In The Closed State Induces Potent Neutralizing Responses
    George W. Carnell, bioRxiv (2021)
  • First Report Demonstrating The Safety And Immunogenicity Of The SARS-COV-2 BNT162b1 mRNA Vaccine In Younger And Older Chinese Adults: A Randomized, Placebo-Controlled, Observer-Blind Phase I Study
    Fengcai Zhu, Research Square (2021)
  • Poor Anti-SARS-CoV-2 Humoral and T-cell Responses After 2 Injections of mRNA Vaccine in Kidney Transplant Recipients Treated With Belatacept
    Nathalie Chavator et al., Transplantation, (2021)
  • SARS-CoV-2 Specific Memory T Cell Epitopes Identified in COVID-19-Recovered Subjects
    Juan Zhao et al., Virus Res, (2021)
  • SARS-CoV2 Mutant-Specific T Cells and Neutralizing Antibodies After Vaccination and up to 1 Year After Infection
    Richardson, J.R. et al., ISAR Bioscience, (2021)
  • COVID-19 Subunit Vaccine with a Combination of TLR1/2 and TLR3 Agonists Induces Robust and Protective Immunity
    Soo-Kyung Jeong et al., Vaccines, (2021)
  • Impairment of CD4+ T and Memory B Cell Responses but Normal Memory CD8+T-Cell Activation on Crohn’s Disease after COVID-19 Vaccination: A Twin Case
    Fabiana Gil-Melgaço et al., Viruses, (2021)
  • Weak Immunogenicity of SARS-CoV-2 Vaccine in Patients With Hematologic Malignancies
    Florent Malard et al., Blood Cancer J, (2021)
  • CD4+ T Cells of Prostate Cancer Patients Have Decreased Immune Responses to Antigens Derived From SARS-CoV-2 Spike
    Pavla Taborska et al., Front Immunol, (2021)
  • T Cell–Mediated Response to SARS-CoV-2 in Liver Transplant Recipients With Prior COVID-19
    Mario Fernández-Ruiz et al., Am J Transplant, (2021)
  • Prospective Assessment of SARS-CoV-2 Seroconversion (PASS) Study: an Observational Cohort Study of SARS-CoV-2 Infection and Vaccination in Healthcare Workers
    Jackson, B.M. et al., BMC Infect Dis, (2021)
  • Cellular Immunity Predominates Over Humoral Immunity After Homologous and Heterologous mRNA and Vector-Based COVID-19 Vaccine Regimens in Solid Organ Transplant Recipients
    Tina Schmidt et al., Am J Translplant, (2021)
  • The Legacy of Maternal SARS-CoV-2 Infection on the Immunology of the Neonate
    Sarah Gee et al., Nat Immunol, (2021)
  • A Single-Cycle Influenza A Virus-Based SARS-CoV-2 Vaccine Elicits Potent Immune Responses in a Mouse Model
    Surapong Koonpaew et al., Vaccines, (2021)
  • Impact of Multiple Sclerosis Disease-Modifying Therapies on SARS-CoV-2 Vaccine-Induced Antibody and T Cell Immunity
    Sabatino, J.J. et al., MedRxiv, (2021)
  • Complete Protection of Nasal and Lung Airways Against SARS-CoV-2 Challenge by Antibody Plus Th1 Dominant N- and S-Specific T-Cell Responses to Subcutaneous Prime and Thermally-Stable Oral Boost Bivalent hAd5 Vaccination in an NHP Study
    Elizabeth Gabitzsch et al., BioRxiv, (2021)
  • The Evaluation of Novel Oral Vaccines Based on Self-Amplifying RNA Lipid Nanparticles (saRNA LNPs), saRNA Transfected Lactobacillus Plantarum LNPs, and saRNA Transfected Lactobacillus Plantarum to Neutralize SARS-CoV-2 Variants Alpha and Delta
    Reza Keikha et al., Sci Rep, (2021)
  • Single-Dose Intranasal Administration of AdCOVID Elicits Systemic and Mucosal Immunity against SARS-CoV-2 and Fully Protects Mice from Lethal Challenge
    King R.G. et al., Vaccines, (2021)
  • T-Cell and Antibody Immunity After COVID-19 mRNA Vaccines in Healthy and Immunocompromised Subjects-An Exploratory Study
    Rakesh Sindhi et al., MedRxiv, (2021)
  • SARS-CoV-2-Specific Antibody and T Cell Response Kinetics According to Symptom Severity
    Ji Yeun Kim et al., Am J Trop Med Hyg, (2021)
  • Implementation of Adenovirus-Mediated Pulmonary Expression of Human ACE2 in HLA Transgenic Mice Enables Establishment of a COVID-19 Murine Model for Assessment of Immune Responses to SARS-CoV-2 Infection
    Theodor Chitlaru et al., Pathogens, (2021)
  • Dynamics of Antibody Response to BNT162b2 Vaccine After Six Months: a Longitudinal Prospective Study
    Naaber, Paul et al., Lancet Reg Health Eur, (2021)
  • Safety and Immunogenicity of an Inactivated Recombinant Newcastle Disease Virus Vaccine Expressing SARS-CoV-2 Spike: Interim Results of a Randomised, Placebo-Controlled, Phase 1/2 Trial
    Punnee Pitisuttihum et al., MedRxiv, (2021)
  • Protracted yet Coordinated Differentiation of Long-Lived SARS-CoV-2-Specific CD8+ T Cells During COVID-19 Convalescence
    Tongcui Ma et al., BioRxiv, (2021)
  • SARS-Cov-2 Spike Protein Fragment 674–685 Protects Mitochondria From Releasing Cytochrome c in Response to Apoptogenic Influence
    Olena Kalashnyk et al., Biochem Biophys Res Commun, (2021)
  • CD8+PD-L1+CXCR3+ Polyfunctional T Cell Abundances Are Associated With Survival in Critical SARS-CoV-2–Infected Patients
    Lucille Adam et al., JCI Insight, (2021)
  • Protective Antibodies Elicited by SARS-CoV-2 Spike Protein Vaccination are Boosted in the Lung After Challenge in Nonhuman Primates
    Joseph R. Francica et al., Sci Transl Med, (2021)
  • Profiling SARS-CoV-2 HLA-I Peptidome Reveals T Cell Epitopes From Out-of-Frame ORFs
    Shira Weingarten-Gabbay et al., Cell, (2021)
  • A Short Corticosteroid Course Reduces Symptoms and Immunological Alterations Underlying Long-COVID
    Alberto Utrero-Rico et al., Biomedicines, (2021)
  • COVID-19 Vaccine mRNA-1273 Elicits a Protective Immune Profile in Mice That is not Associated With Vaccine-Enhanced Disease Upon SARS-CoV-2 Challenge
    DiPiazza, A.T. et al., Immunity, (2021)
  • An Enveloped Virus-Like Particle Vaccine Expressing a Stabilized Prefusion form of the SARS-CoV-2 spike Protein Elicits Highly Potent Immunity
    Anne-Catherine Fluckiger et al., Vaccine, (2021)
  • Intranasal Plus Subcutaneous Prime Vaccination With a Dual Antigen COVID-19 Vaccine Elicits T-Cell and Antibody Responses in Mice
    Adrian Rice et al., Sci Rep, (2021)
  • Change in Symptoms and Immune Response in People with Post-Acute Sequelae of SARS-Cov-2 Infection (PASC) After SARS-Cov-2 Vaccination
    Daisy Massay et al., MedRxiv, (2021)
  • Evolution of SARS-CoV-2 Immune Responses in Nursing Home Residents Following Full Dose of the Comirnaty® COVID-19 Vaccine
    Giménez, E. et al., J Infect (2021)
  • Correlates of Neutralization against SARS-CoV-2 Variants of Concern by Early Pandemic Sera
    Vidal, S-J. et al., J Virol, (2021)
  • Preserved T-cell Response in anti-CD20 Treated Multiple Sclerosis Patients Following SARS-CoV-2 Vaccination
    Simon Faissner et al., Res Square, (2021)
  • Durable T cell responses contrast with faster antibody waning in BNT162b2-vaccinated elderly at 6 month
    Laurent Renia et al., Res Square, (2021)
  • SARS-CoV-2 ferritin nanoparticle vaccine induces robust innate immune activity driving polyfunctional spike-specific T cell responses
    Joshua M. Carmen et al., Vaccines, (2021)
  • A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates
    M. Gordon Joyce et al., Science Translational Medicine
  • SARS-CoV-2-Specific Cell-Mediated Immunity in Kidney Transplant Recipients Recovered From COVID-19
    Mario Fernández-Ruiz et al., Transplantation, (2021)
  • SARS-CoV-2 Vaccination in Rituximab-Treated Patients: B Cells Promote Humoral Immune Responses in the Presence of T-Cell-Mediated Immunity
    Daniel Mrak et al., Ann Rheum Dis, (2021)
  • Comorbid Illnesses are Associated With Altered Adaptive Immune Responses to SARS-CoV-2
    Krystle Kq Yu et al., JCI Insight, (2021)
  • Longitudinal Analysis of Human Memory T-Cell Response According to the Severity of Illness up to 8 Months After Severe Acute Respiratory Syndrome Coronavirus 2 Infection
    Chang Kyung Kang et al., J Infect Dis, (2021)
  • Deconvoluting the T Cell Response to SARS-CoV-2: Specificity Versus Chance and Cognate Cross-Reactivity
    Alexander A. Lehmann et al., Front Immunology, (2021)
  • Identification of Conserved SARS-CoV-2 Spike Epitopes That Expand Public cTfh Clonotypes in Mild COVID-19 Patients
    Xiuyuan Lu et al., J Exp Med, (2021)
  • Effectiveness of ChAdOx1 nCoV-19 Vaccine Against SARS-CoV-2 Infection During the Delta (B.1.617.2) Variant Surge in India: a Test-Negative, Case-Control Study and a Mechanistic Study of Post-Vaccination Immune Responses
    Ramachandran Thiruvengadam et al., Lancet Infect Dis, (2021)
  • Acute Exercise Increases Immune Responses to SARS CoV-2 in a Previously Infected Man
    Baker, F. L. et al., Brain Behav Immun Health (2021)
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