Peptide Synthesis

At JPT Peptide Technologies, we are recognized as the peptide synthesis experts. With over 20 years of experience, we deliver high-quality custom peptides, libraries, and pools tailored to your research needs. Our patented platforms for microarrays, micro-scale synthesis, peptide libraries and peptide pools combine innovation with precision, ensuring reproducible results from small research quantities to large-scale peptide production. All synthesis is performed in our state-of-the-art laboratories in Berlin, guaranteeing consistency, quality, and reliability for global scientific and industrial applications.


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Peptide Synthesis Services

Custom Peptide Synthesis for Any Application 


Our peptide synthesis services support projects from micro to large scale, offering flexible purity levels, a wide range of peptide modifications, and multiple delivery formats. Each peptide is produced with robust quality control to ensure reliable results for diverse research applications

  • Micro-scale synthesis (10–50µg) for high-throughput experiments 
  • Mid-scale synthesis (1 mg–1 g) 
  • Large-scale peptide synthesis (>1 g)
We accommodate a wide range of peptide modifications, including biotinylation, phosphorylation, stable-isotope labeling, and cyclization. Additional services such as aliquoting, pooling, solubility testing, and stability assessment ensure that your synthetic peptides are ready for immediate application. Whether you require simple sequences or complex, post-translationally modified peptides, JPT provides precision peptide synthesis to meet the highest research and industry standards.

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Variety of Our Peptide Synthesis Services


Quantity
Purity
Modifications
Format
Optional Quantification
Applications
Benefits
Micro Scale Peptide Synthesis10 - 50µgcrudemodified aa, biotin, phosphorylation, stable-isotope labeled ...tubes, pools, microtiter plates, microarrays, cellulose, ELISAOptical Densityresearch useFrom only 15€/US$19.50 per peptide! 
>50,000 peptides/month
Mid Scale Synthesis
1mg - 1gcrude to >95%modified aa, biotin, phosphorylation, stable-isotope labeled, AQUA, cyclization…
tubes, pools, tube racks, ELISAQ tag, AAAresearch use, immunomonitoring, cell therapy development, clinical trial immune monitoringPremium quality >5000 peptides/month
Large Scale Synthesis> 1gcrude to >95%modified aa, biotin, phosphorylation, stable-isotope labeled, cyclization, lipids, TFA removal…tubes, poolsQ tag, AAAresearch use, immunomonitoring, cell therapy development, clinical trial immune monitoringEndless range of modifications

Why Choose JPT?


  • ISO 9001:2015 Certified: Our processes follow rigorous, audited quality standards for consistent and dependable peptide synthesis.
  • Berlin-Based Manufacturing: All peptide synthesis is performed in our Berlin facilities, ensuring controlled, reliable production. 
  • Global Scientific Support: With teams in Berlin, the UK and the US, expert guidance is available for any peptide-related project. 
  • Two Decades of Expertise: Our long-standing experience positions us as true leaders in the peptide synthesis industry. 
  • Ethical and Sustainable Practices: We maintain strict environmental, health, and ethical standards across all production steps. 
  • A BioNTech Company: Since 2009, our connection to BioNTech provides access to cutting-edge biotechnological advances applied to peptide synthesis technologies.

JPT's Popular Peptide Synthesis Services

Custom Peptide Synthesis

JPT produces high-quality custom peptides with over two decades of expertise and a success rate above 99% in custom peptide synthesis.


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Peptide Libraries

Custom peptide libraries optimized for cellular and other assays with flexible options for purity, quantity, delivery format, QC, and modifications.

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Peptide Pools

PepMix™ peptide pools deliver efficient stimulation of antigen-specific T cells, offering advantages over full-length proteins.

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Peptide Modifications

Specialized synthesis of long, cyclized, heavy- or dye-labeled peptides and other PTMs using expert-level techniques.


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Bioconjugated Peptides

Comprehensive conjugation services for generating peptide–protein, peptide–lipid, peptide–oligonucleotide, and other molecular conjugates.

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Peptide Arrays & Microarrays

High-throughput peptide arrays for profiling protein interactions, epitope mapping, and enzymatic activity.


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Critical Raw Material

ISO PLUS peptides provide high-purity, traceable critical raw materials for clinical, IVD, and regulated research applications as well as clinical immune monitoring.

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Peptide ELISA

Peptide ELISA platforms enable precise sequence-level epitope mapping or identification of protein-protein interaction binding siteswith exceptional reproducibility. 

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Peptide Analysis

Comprehensive chemical, biological, and bioinformatics analysis services supporting peptide characterization and QC for documentation and regulations.

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Testimonials

"The RV 144 HIV trial is considered as one of first successful HIV vaccine trials. The use of JPT's PepStarTM microarray technology has been very useful for the correlation of the clincial outcome with humoral immune responses. As have the cyclic peptides been from JPT to validate these findings!"

J. Currier, PhD, Walter Reed Army Institute, Rockville, Maryland, USA

"We utilize customized 15-mer PepMix™ peptide pools encoding for weak tumor associated antigens for immunomonitoring of cancer patients treated with recombinant therapeutic vaccines. Our experience with JPT has been outstanding in regard to product quality and communication with scientific and administrative customer service."

Benedetto Farsaci, MD, National Cancer Institute, NIH, Bethesda, MD, USA

"Our teams at the Vrije Universiteit Brussel deal with a wide variety of projects in different areas of applied biological sciences. For many of them we are in need of peptide related tools and services and we are collaborating with JPT for many years and are very satisfied with the relationship which led to several well received publications."

Prof. Dr. Joost Schymkowitz (Vrije Universiteit, Brussel, Belgium)

FAQs 

What peptide lengths can JPT synthesize?

JPT manufactures short, medium, and long peptides up to 50 aa in routine. Longer peptides can be prepared in projects.

How can I design my peptide library or pool?

Use JPT's PepSequencer Peptide Design Tool.  Our scientific experts can also advise on sequence design, solubility, modifications, and project strategy .

What methods does JPT use to synthesize peptides?

We use Fmoc solid-phase peptide synthesis (SPPS) for most peptides, SPOT synthesis for high-throughput libraries, and ligation or fragment condensation for very long or difficult sequences. Click chemistry is used to accommodate complex modifications or structures.

Can JPT synthesize peptides with unusual residues?

Yes. We routinely produce peptides containing non-natural amino acids, non-commercially available amino acids, and post-translational modifications.


What is the difference between peptide content and peptide weight?

Peptide weight includes moisture and counter-ions from lyophilization. Peptide content reflects the pure peptide amount determined via quantitative amino acid analysis.

How to dissolve peptides?

Charged peptides dissolve best in aqueous buffers, while hydrophobic peptides may require initial solubilization in organic solvents such as DMSO or DMF. For more information visit our page on Dissolving Peptides. 

How do we avoid cross-contamination?

We prevent cross-contamination using dedicated equipment, single-use consumables, strict cleaning protocols, and segregated workflows aligned with the required quality grade.

Does JPT consider sequence diversity?

Yes. With our ULTRA bioinformatics approach, we design peptide libraries that cover all relevant sequence variations across viral, bacterial, or cancer-related targets.

Can you synthesize modified peptides?

Absolutely. We specialize in phosphorylation, methylation, glycosylation, and other key post-translational modifications, as well as peptide modifications such as cyclization, dye or heavy labeling, and more. Have a look!

What does ISO 9001 certification mean?

It confirms that JPT operates a robust Quality Management System according to the latest ISO 9001:2015 standards that ensures consistent and transparent peptide synthesis processes.

What does average purity mean at JPT?

Unlike suppliers who report only an average, JPT guarantees that each peptide in a pool or library meets the stated purity.

How do you reduce toxic by-products during synthesis?

To reduce toxic synthesis by-products, we purify all peptides with a guaranteed purity level regardless of whether the initial crude material already meets the target purity or not, which significantly reduces chemicals from the synthesis process. If your assay or application is very sensitive, we can substitute TFA with chloride or acetate.

How do you avoid de novo epitope formation?

Our proprietary capping technology reduces unwanted deletion sequences that can cause false positive results.
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Contact Us

Customer Support


peptide@jpt.com 
T: +49-30-322980-7878

Technical Support Europe

T: +49-30-322980-7830
T: +49-30-322980-7632

Technical Support North America

T: 888.JPT.COM0 (888-578-2660)
X: 888.JPT.COM6 (888-578-2666)

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