β-amyloid monomer scavenging by an anticalin protein prevents neuronal hyperactivity in mouse models of Alzheimer’s Disease Zott et al., Nature Communications (2024) - PMID: 38987287
Novel 6-hydroxybenzothiazol-2-carboxamides as potent and selective monoamine oxidase B inhibitors endowed with neuroprotective activity Al-Saad et al., European Journal of Medicinal Chemistry (2024) - PMID: 38490063
2023
2023
Residue‑specifc binding of Ni(II) ions infuences the structure and aggregation of amyloid beta (Aβ) peptides Berntsson et al., Scientific Reports (2023) - PMID: 36849796
β-amyloid monomer scavenging by an anticalin protein prevents neuronal hyperactivity Zott et al., Research Square (2023)
Archive
Archive
Isotope-labeled amyloid-bdoes not transmit to thebrain in a prion-like manner after peripheraladministration Brackhan et al., EMBO Reports (2022)
A Highly Specific Assay for the Detection of SARS-CoV-2–Reactive CD4+ and CD8+ T Cells in COVID-19 Patients Zelba et al., J Immunology, (2021)
Citrullination of Amyloid-β Peptides in Alzheimer’s Disease Soumya Mukherjee et al., ACS Chem Neurosci., (2021)
SARS-CoV-2 Protein Subunit Vaccination of Mice and Rhesus Macaques Elicits Potent and Durable Neutralizing Antibody Responses Mandolesi et al., Cell Rep Med, (2021)
Single Prime hAd5 Spike (S) + Nucleocapsid (N) Dual Antigen Vaccination of Healthy Volunteers Induces a Ten-Fold Increase in Mean S- and N- T-Cell Responses Equivalent to T-Cell Responses from Patients Previously Infected with SARS-CoV-2 Sieling et al., medRxiv, (2021)
Long‑term cafeine treatment of Alzheimer mouse models ameliorates behavioural defcits and neuron loss and promotes cellular and molecular markers of neurogenesis Stazi et al., Cellular and Molecular Life Science, (2021)
Population Imaging of SynapticallyReleased Glutamate in Mouse Hippocampal Slices Unger et al., STAR Protocols, (2021)
A Rapid and Reliable Liquid Chromatography/mass Spectrometry Method for SARS-CoV-2 Analysis from Gargle Solutions and Saliva Kipping et al., Analytic & Bioanalytic Chem., (2021)
COVID-19 Subunit Vaccine with a Combination of TLR1/2 and TLR3 Agonists Induces Robust and Protective Immunity Soo-Kyung Jeong et al., Vaccine, (2021)
JNJ-64794964 (AL-034/TQ-A3334), a TLR7 Agonist, Induces Sustained Anti-HBV Activity in AAV/HBV Mice Via Non-Cytolytic Mechanisms Herschke et al., Antiviral Res (2021)
R1441G but not G2019S Mutation Enhances LRRK2 Mediated Rab10 Phosphorylation in Human Peripheral Blood Neutrophils Ying Fan et al., Acta Neuropathol. (2021)
Sulfated Lactosyl Archaeol Archaeosomes Synergize with Poly(I:C) to Enhance the Immunogenicity and Efficacy of a Synthetic Long Peptide-Based Vaccine in a Melanoma Tumor Model Akache et al., Pharmaceutical Research, (2021
A Comparative Study of the Effects of Aducanumab and Scanning Ultrasound on Amyloid Plaques and Behavior in the APP23 Mouse Model of Alzheimer Disease Leinenga et al., bioRxiv (2020) - PMID: n.a.
Lithium Ions Display Weak Interaction With Amyloid-Beta (Aβ) Peptides And Have Minor Effects On Their Aggregation Berntsson et al., BioRxiv (2020) - PMID: n.a.
Analyzing Microglial‑Associated Aβ in Alzheimer’s Disease Transgenic Mice With a Novel Mid‑Domain Aβ‑Antibody Henjum et al., Scientific Reports (2020) - PMID: 32601313
In Situ Structural Characterization of Early Amyloid Aggregates in Alzheimer’s Disease Transgenic Mice And Octodon Degus Benseny-Cases et al., Scientific Reports (2020) - PMID: 32246090
Metal- and UV- catalyzed oxidation results in trapped amyloid-ß intermediates revealing that self-assembly is required for Aß-induced cytotoxicity Maina et al., iScience (2020) -
Misfolded Amyloid-β-42 Impairs The Endosomal–Lysosomal Pathway Marshall et al., Cellular and Molecular Life Sciences (2020) - PMID: 32025743
Method For Detecting Aggregate Of Aggregate - Forming Polypeptidemethod For Detecting Aggregate Of Aggregate - Forming Polypeptide Byoung Sub LEE et al., Patent Application Publication (2019) - PMID: n.a.
Novel D - Enantiomeric Peptides Derived From D3 And Use Thereof Willbold et al., Patent Application Publication (2019) - PMID: n.a.
Poly(propylene imine) Dendrimers With Histidine-Maltose Shell as Novel Type of Nanoparticles for Synapse and Memory Protection Aso et al., Nanomedicine: Nanotechnology, Biology and Medicine (2019) - PMID: 30708052
The Metalloprotease ADAMTS4 Generates N-truncated Aβ4–x Species and Marks Oligodendrocytes as a Source of Amyloidogenic Peptides in Alzheimer’s Disease Walter et al., Acta Neuropathologica (2018) - PMID: 30426203
Amyloid-Peptide β 42 Enhances the Oligomerization and Neurotoxicity of apoE4: The C-Terminal Residues Leu279, Lys282 and Gln284 Modulate the Structural and Functional Properties of apoE4. Dafnis et al., Neuroscience (2018) - PMID: 30367942
A Peptide or Collection of Peptides Derived from Amyloid Precursor Protein Willem et al., US Patent App. 15/559,613, 2018 (2018) - PMID: n.a.
Synchrotron-Based µFTIR Study on the Effect of Alzheimer´s Aβ Amorphous and Fibrillar Aggregates on PC12 Cells Benseny-Cases et al., Analytical Chemistry (2018) - PMID: 29359921
High Affinity Binding of Monomeric, but not Oligomeric Amyloid-β to Ganglioside GM1 Containing Nanodiscs Thomaier et al., Biochemistry (2016) - PMID: n.a.
Limited Effects of Prolonged Environmental Enrichment on the Pathology of 5XFAD Mice Hüttenrauch et al., Molecular Neurobiology (2016) - PMID: 27734334
A Critical Role For the Self-Assembly of Amyloid-β1-42 in Neurodegeneration Marshall et al., Scientific reports (2016) - PMID: 27443509
Characterization of Insulin-Degrading Enzyme-Mediated Cleavage of Aβ in Distinct Aggregation States Hubin et al., Biochim Biophys Acta. (2016) - PMID: 26968463
Assessment of Structural Properties of Amyloid Aggregates and Their Application Potential Thangaraj et al., Dissertation for the University of Ulm (2016) - PMID: n.a.
Inhibition of the Cardiac Na+ Channel α-Subunit Nav1. 5 by Propofol and Dexmedetomidine Stoetzer et al., Naunyn Schmiedebergs Arch Pharmacol. - PMID: 26667357
Aβ-42 Lowering Agents From the Marine-Derived Fungus Dichotomomyces Cejpii Harms et al., Steroids. (2015) - PMID: 26440473
η-Secretase Processing of APP Inhibits Neuronal Activity in the Hippocampus Willem et al., Nature (2015) - PMID: 26322584
Hybridization of an Aβ-Specific Antibody Fragment with Aminopyrazole-Based β Sheet Ligands Displays Striking Enhancement of Target Affinity Hellmert et al., Org. Biomol. Chem. (2015) - PMID: n.a.
Neprilysin Deficiency Alters the Neuropathological and Behavioral Phenotype in the 5XFAD Mouse Model of Alzheimer's Disease Huettenrauch et al., J Alzheimers Dis. (2014) - PMID: 25408216
Monoclonal Antibodies Against Ab42 Fibrils Distinguish Multiple Aggregation State Polymorphisms in vitro and in Alzheimer's Disease Brain Hatami et al., J. Biol. Chem. (2014) - PMID: 25281743
The Alzheimer Disease Protective Mutation A2T Modulates Kinetic and Thermodynamic Properties of Amyloid-β (Aβ) Aggregation Benilova et al., J. Biol. Chem. (2014) - PMID: 25253695
Structure and Biomedical Applications of Amyloid Oligomer Nanoparticles Kumar et al., ACS nano (2014) - PMID: 25337989
Molecular Basis for Increased Risk for Late-onset Alzheimer Disease Due to the Naturally Occurring L28P Mutation in Apolipoprotein E4 Argyri et al., J. Biol. Chem. (2014) - PMID: 24644280
The D-Amino Acid Peptide D3 Reduces Amyloid Fibril Boosted HIV-1 Infectivity Widera et al., AIDS Res. Ther. (2014) - PMID: 24422713
Characterization of a Single-Chain Variable Fragment Recognizing a Linear Epitope of Aβ: A Biotechnical Tool for Studies on Alzheimer’s Disease? Dornieden et al., PLoS One (2013) - PMID: 23555792
Effect of Poly(propylene imine) Glycodendrimers on β-Amyloid Aggregation in Vitro and in APP/PS1 Transgenic Mice, as a Model of Brain Amyloid Deposition and Alzheimer’s Disease Klementieva et al., Biomacromolecules (2013) - PMID: 24004423
Nanoparticulate Flurbiprofen Reduces Amyloid-β42 Generation in an in Vitro Blood-Brain Barrier Model Meister et al., Alzheimers Research & Therapy (2013) - PMID: 24280275
The Amyloid-β Oligomer Count in Cerebrospinal Fluid is a Biomarker for Alzheimer's Disease Wang-Dietrich et al., Journal of Alzheimer's Disease (2013) - PMID: 23313925
Exploring the Sequence–Structure Relationship for Amyloid Peptides Morris et al., Biochem. J. (2013) - PMID: 23252554
Analysis of Quality, Aggregation and Toxicity of Amyloid Beta Peptide Produced by JPT Vandersteen et al., Report (2011)
Active Immunization with Amyloid-β 1–42 Impairs Memory Performance through TLR2/4-Dependent Activation of the Innate Immune System Vollmar et al., J. Immunol. (2010) - PMID: 20943998
Mechanism of Amyloid Plaque Formation Suggests an Intracellular Basis of Aβ Pathogenicity Friedrich et al., PNAS (2010) - PMID: 20133839
Novel Mediators of Amyloid Precursor Protein Signaling Swistowski et al., J. Neurosci. (2009) - PMID: 20016085
DNA Beta-Amyloid1-42 Trimer Immunization for Alzheimer Disease in a Wild-Type Mouse Model Lambracht-Washington et al., JAMA, (2009) - PMID: 19861672
Vaccination with Prion Peptide-Displaying Papillomavirus-like Particles Induces Autoantibodies to Normal Prion Protein that Interfere with Pathologic Prion Protein Production in Infected Cells Handisurya et al., FEBS Journal (2007) - PMID: 17313482
In Vitro Characterization of Conditions for Amyloid-β Peptide Oligomerization and Fibrillogenesis Stine et al., J Biol Chem. (2003) - PMID: 12499373
