Chronic Fatigue Syndrome
Development of Peptide-Based Assays to Diagnose Chronic Fatigue Syndrome (CFS)
Chronic fatigue syndrome (CFS) is a severe disease characterized by various symptoms of immune dysfunction. CFS onset typically is associated with an infection and many patients suffer from frequently recurrent viral or bacterial infections. Epstein-Barr virus (EBV) has long been discussed as a possible cause or trigger for CFS. To date, there is no marker or single test to confirm a diagnosis of CFS.
The aim of the longtime collaboration with the team of Prof. Scheibenbogen from the Charité (Institute for Medical Immunology) is to distinguish CFS from other disease (e.g. depression) based on the disturbed immune response against EBV. The current project comprises the development of peptide-based assays for this purpose and is funded by the European Union and the program "Investition in Ihre Zukunft".