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JPT's Absolute Quantified Peptides for Research


SpikeTides™ TQL and SpikeTides™ TQL PLUS are advanced peptide products that provide absolute quantification, offering high precision for the analysis of antigen-specific immune responses. These products are particularly useful for assessing the immune landscape in infectious diseases, cancer immunotherapy, and vaccine development. Below, you will find a key study referencing JPT’s SpikeTides™ TQL & SpikeTides™ TQL PLUS in research.

References with Absolute Quantified Peptides - SpikeTides™ TQL & SpikeTides™ TQL PLUS

2025

2025

  • A novel paracetamol derivative alleviates lipopolysaccharide-induced neuroinflammation
    Králová et al., European Journal of Pharmacology (2025) - PMID: 39986592
  • A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8+ infiltration in glioma
    Singh et al., Nature Communications (2025) 
2024

2024

  • High-affinity T cell receptor ImmTAC® bispecific efficiently redirects T cells to kill tumor cells expressing the cancer testis antigen PRAME.
    Ribeiro et al., Immunotherapy Advances (2024) 
  • Multianalytical Approach to Understand Polyphenol-Mal d 1 Interactions to Predict Their Impact on the Allergenic Potential of Apples
    Kaeswurm et al., Journal of Agricultural and Food Chemistry (2024) - PMID: 38990326
    Products used: Custom SpikeTides TQL
  • Development of an Absolute Quantification Method for hERG UsingPRM with Single Isotopologue in-Sample Calibration
    Chang et al., ACS Publications (2024) - PMID: 39130540
    Products used: Custom SpikeTides TQL
Archive

Archive

  • Multianalytical Approach to Understand Polyphenol-Mal d 1 Interactions to Predict Their Impact on the Allergenic Potential of Apples
    Kaeswurm et al., Journal of Agricultural and Food Chemistry (2024) 
  • Validation of circulating histone detection by mass spectrometry for early diagnosis, prognosis, and management of critically ill septic patients
    García‑Giménez et al., Journal of Translational Medicine (2023) - PMID: 37221624
  • Immuno-Mass Spectrometry Workflow for Quantification of Serum α-Fetoprotein Using Antibody-Immobilized Magnetic Beads and Modified Eluents
    Takahata et al., Mass Spectrometry (2023) - PMID: 37260735
  • Development of a Rapid and Specific MALDI-TOF Mass Spectrometric Assay for SARS-CoV-2 Detection
    Kollhoff et al., MedRxiv (2023) - PMID: 37393264
  • The structural components of the Azotobacter vinelandii iron-only nitrogenase, AnfDKG, form a protein complex within the plant mitochondrial matrix
    Johnston et al., Plant Molecular Biology (2023) - PMID: 37326800
  • A “best-in-class” systemic biomarker predictor of clinically relevant knee osteoarthritis structural and pain progression
    Zhou et al., Science Advances (2023) - PMID: 36696492
  • Serum proteomic panel validated for prediction of knee osteoarthritis progression
    Kraus et al., Osteoarthritis and Cartilage Open (2023) - PMID: 38116469
  • Aldehyde oxidase 1 activity and protein expression in human, rabbit, and pig ocular tissues
    Hammid et al., European Journal of Pharmaceutical Sciences (2023) - PMID: 37827455
    Products used: Custom SpikeTides TQL
  • Identification and verification of plasma protein biomarkers that accurately identify an ectopic pregnancy
    Beer et al., Clinical Proteomics (2023)
    Product used: Custom SpikeTides TQL
  • Prosit-TMT: Deep Learning Boosts Identification of TMT-Labeled Peptides
    Gabriel et al., Analytical Chemistry (2022) - PMID: 35549156
  • Metabolomic, lipidomic and proteomic characterisation of lipopolysacchar‐ide-induced inflammation mouse model
    Puris et al., Neuroscience (2022) - PMID: 35636730
  • Selective quantifcation of the 22‑kDa isoform of human growth hormone 1 in serum and plasma by immunocapture and LC–MS/MS
    Sleumer et al., Analytical and Bioanalytical Chemistry (2022) - PMID: 35838770
  • Serum amyloid P component and pro-platelet basic protein in extracellular vesicles or serum are novel markers of liver fibrosis in chronic hepatitis C patients
    Shirai et al., PLOS One (2022) - PMID: 35797333
  • Increased Expression and Activity of Brain Cortical cPLA2 Due to Chronic Lipopolysaccharide Administration in Mouse Model of Familial Alzheimer’s Disease
    Gynther et al., Pharmaceutics (2022) 
  • Development of immuno-affinity mass spectrometry assays for the detection and quantification of viral antigens and antibodies
    Dara, Thesis (2022)
  • Protein Expression of Amino Acid Transporters Is Altered in Isolated Cerebral Microvessels of 5xFAD Mouse Model of Alzheimer’s Disease
    Puris et al., Molecular Neurobiology (2022)
  • Air pollution exposure increases ABCB1 and ASCT1 transporter levels in mouse cortex
    Puris et al., Environmental Toxicology and Pharmacology (2022)
  • Analysis of flagellar proteins in Clostridium difficile isolates of clinically relevant PCR-ribotypes
    Králové, Dissertation (2022)
  • Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor
    Bröker et al., Journal of Medicinal Chemistry (2022)
  • L‑type Amino Acid Transporter 1 Utilizing Ferulic Acid Derivatives Show Increased Drug Delivery in the Mouse Pancreas Along with Decreased Lipid Peroxidation and Prostaglandin Production
    Tampio et al., Molecular Pharmaceutics
  • Plasma apolipoprotein E levels in longitudinally followed patients with mild cognitive impairment and Alzheimer’s disease
    Giannisis et al., Alzheimer's Research & Therapy (2022)
  • Functional in vitro characterization of SLCO1B1 variants and simulation of the clinical pharmacokinetic impact of impaired OATP1B1 function
    Wilma et al., Pharmaceutical Sciences (2022)
  • Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation
    Theilgaard-Mönch et al., Nature Communications (2022) 
  • Proteomics for Development of Food Allergy Vaccines
    Mónica Carrera & Susana Magadán, Vaccine Design (2022) - PMID: 34914075
  • Use of MS-GUIDE for identifcation of protein biomarkers for risk stratifcation of patients with prostate cancer
    Goetze et al., Clinical Proteomics (2022) - PMID : 35477343
  • Systemic Inflammation Induced Changes in Protein Expression of ABC Transporters and Ionotropic Glutamate Receptor Subunit 1 in the Cerebral Cortex of Familial Alzheimer`s Disease Mouse Model
    Elena Puris et al., J Pharm Sci, (2021) - PMID : 34403652
  • New Approaches for Absolute Quantification of Stable‐Isotope‐Labeled Peptide Standards for Targeted Proteomics based on a UV Active Tag
    Karsten Schnatbaum et al., Proteomics (2020) - PMID: 32267065
  • Endogenous Coproporphyrin I and III are Altered in Multidrug Resistance-Associated Protein 2-Deficient (TR−) Rats
    Jaqueline Bezençon et al., Journal of Pharmaceuticals, (2021)
  • Proteogenomic Approach to UTR Peptides Identification
    Seunghyuk Choi et al., Journal of Proteome Research (2019) - PMID: 31714086
  • Potential Roles of Gut Microbiome and Metabolites in Modulating ALS in Mice
    Eran Blacher et al., Nature (2019) - PMID: 31330533
  • Mechanistic Study on the Use of the l-Type Amino Acid Transporter 1 for Brain Intracellular Delivery of Ketoprofen via Prodrug: A Novel Approach Supporting the Development of Prodrugs for Intracellular Targets
    Elena Puris et al., Molecular Pharmaceutics (2019) - PMID: 31180686
  • Development of Targeted Mass Spectrometry-Based Approaches for Quantitation of Proteins Enriched in the Postsynaptic Density (PSD)
    Rashaun S. Wilson et al., Proteomes (2019) - PMID: 30986977
  • Quantitation of Seven Transmembrane Proteins From the DHA Biosynthesis Pathway in Genetically Engineered Canola by Targeted Mass Spectrometry
    Michelle L.Colgrave et al., Food and Chemical Toxicology (2019) - PMID: 30831153
  • Postmortem Protein Stability Investigations of the Human Hepatic Drug-Metabolizing Cytochrome P450 Enzymes CYP1A2 and CYP3A4 Using Mass Spectrometry
    Jakob Hansena et al., Journal of Proteomics (2018) - PMID: 30529742
  • Layers of Regulation on Cell-Cycle Gene Expression in the Budding Yeast Saccharomyces Cerevisiae
    Kelliher et al., Molecular biology of the cell (2018) - PMID: 30207828
  • Using Stepwise Pharmacogenomics and Proteomics to Predict Hepatitis C Treatment Response in Difficult to Treat Patient Populations
    Naggie et al., PROTEOMICS – Clinical Applications (2018) - PMID: 30058111
  • Quantification of Membrane Transporter Proteins in Human Lung and Immortalized Cell Lines Using Targeted Quantitative Proteomic Analysis by Isotope Dilution NanoLC-MS/MS.
    Fallon et al., J Pharm Biomed Anal. (2018) - PMID: 29544106
  • Stereocilia-Staircase Spacing Is Influenced By Myosin III Motors and Their Cargos Espin-1 and Espin-like
    Ebrahim et al., nature communications (2018) - PMID: 26926603
  • A New Mass Spectrometry-Based Method for the Quantification of Histones in Plasma from Septic Shock Patients
    García-Giménez et al., Scientific Reports (2018) - PMID: 28878320
  • A Crude-MS Strategy for in-Depth Proteome Analysis of the Methane-Oxidizing Methylocystis sp. Strain SC2
    Hakobyan et al., J. Proteome Res (2018) - PMID: 30019905
  • Biochemical Characterization of Human Tissue Kallikrein 15 and Examination of its Potential Role in Cancer
    Filippou et al., Clinical Biochemistry (2018) - PMID: 29928903
  • Expression Profile of Human Tissue Kallikrein 15 Provides Preliminary Insights Into its Roles in the Prostate and Testis
    Filippou et al., Clinical Biochemistry (2018) - PMID: 29958881
  • Quantification of Membrane Transporter Proteins in Human Lung and Immortalized Cell Lines Using Targeted Quantitative Proteomic Analysis by Isotope Dilution nanoLC-MS/MS
    Fallon et al., Journal of Pharmaceutical and Biomedical Analysis (2018) - PMID: n.a.
  • Quantitative Multiple Reaction Monitoring Proteomic Analysis of Gβ and Gγ Subunits in C57Bl6/J Brain Synaptosomes
    Yim et al., Biochemistry (2017) - PMID: 28880079
  • The Normal Trachea is Cleaned by MUC5B Mucin Bundles from the Submucosal Glands Coated with the MUC5AC Mucin
    Ermund et al., Biochem Biophys Res Commun. (2017) - PMID: 28859985
  • Preclinical Evaluation of a TEX101 Protein ELISA Test for the Differential Diagnosis of Male Infertility
    Korbakis et al., BMC Medicine (2017) - PMID: 28330469
  • Absolute Quantification of Myosin Heavy Chain Isoforms by Selected Reaction Monitoring Can Underscore Skeletal Muscle Changes in a Mouse Model of Amyotrophic Lateral Sclerosis
    Peggion et al., Analytical and Bioanalytical Chemistry (2017) - PMID: 28078418
  • A New Enzyme-Linked Immunosorbent Assay (ELISA) for Human Free and Bound Kallikrein 9
    Filippou et al., Clinical Proteomics (2017) - PMID: 28115917
  • Plastin 1 Widens Stereocilia by Transforming Actin Filament Packing from Hexagonal to Liquid
    Krey et al., J Cell Biol. (2017) - PMID: 27811163
  • Targeted Proteomics for the Indirect Detection of Dexamethasone Treatment in Bovines
    Stella et al., Analytical and Bioanalytical Chemistry (2016) - PMID: 27695961
  • The Tyrosine Sulfate Domain of Fibromodulin Binds Collagen and Enhances Fibril Formation
    Tillgren et al., Journal of biological Chemistry (2016) - PMID: 27634037
  • Spatially Directed Proteomics of the Human Lens Outer Cortex Reveals an Intermediate Filament Switch Associated With the Remodeling Zone
    Wenke et al., Investigative Ophthalmology & and Visual Science (2016) - PMID: 27537260
  • Argonaute Family Protein Expression in Normal Tissue and Cancer Entities
    Völler et al., PloS one (2016) - PMID: 27518285
  • Quantification of Four Efflux Drug Transporters in Liver and Kidney Across Species Using Targeted Quantitative Proteomics by Isotope Dilution NanoLC-MS/MS
    Fallon et al., Pharmaceutical Research (2016) - PMID: 27356525
  • Molecular and Proteome Analyses Highlight the Importance of the Cpx Envelope Stress System for Acid Stress and Cell Wall Stability in Escherichia coli
    Surmann et al., MicrobiologyOpen (2016) - PMID: 27039284
  • Protein Z: A Putative Novel Biomarker for Early Detection of Ovarian Cancer
    Russell et al., Int J Cancer. (2016) - PMID: 26815306
  • Metabolic Engineering of Clostridium Cellulolyticum for the Production of n-butanol from Crystalline Cellulose
    Gaida et al., Microb Cell Fact. (2016) - PMID: 26758196
  • Application of De Novo Sequencing to Large-Scale Complex Proteomics Datasets
    Devabhaktuni et al., (2016) - PMID: 26743026
  • LC-MS/MS-Based Monitoring of in vivo Protein Biotransformation: Quantitative Determination of Trastuzumab and its Deamidation Products in Human Plasma
    Bults et al., Anal Chem. (2016) - PMID: 26713683
  • Postovulatory Aging Affects Dynamics of mRNA, Expression and Localization of Maternal Effect Proteins, Spindle Integrity and Pericentromeric Proteins in Mouse Oocytes
    Trapphoff et al., Hum. Reprod. (2015) - PMID: n.a
  • Targeted Proteomics-Driven Computational Modeling of Macrophage S1P Chemosensing
    Manes et al., Mol Cell Proteomics (2015) - PMID: 26199343
  • Development of Phage-Based Antibody Fragment Reagents for Affinity Enrichment of Bacterial IgG Binding Proteins
    Säll et al., J Proteome Res. (2015) - PMID: 26452057
  • Needles in the Blue Sea: Sub-Species Specificity in Targeted Protein Biomarker Analyses Within the Vast Oceanic Microbial Metaproteome
    Saito et al., Proteomics (2015) - PMID: 26097212
  • Targeted Proteomics of Human Metapneumovirus in Clinical Samples and Viral Cultures
    Foster et al., Analytical Chemistry (2015) - PMID: 26376123
  • A Multiplexed, Targeted Mass Spectrometry Assay of the S100 Protein Family Uncovers the Isoform-specific Expression in Thyroid Tumours
    Martínez-Aguilar et al., BMC Cancer (2015) - PMID: 26011226
  • Immunocapture-Selected Reaction Monitoring Screening Facilitates the Development of ELISA for the Measurement of Native TEX101 in Biological Fluids
    Korbakis et al., Mol Cell Proteomics (2015) - PMID: 25813379
  • Global and Specific Responses of the Histone Acetylome to Systematic Perturbation
    Feller et al., Mol Cell. (2015) - PMID: 25578876
  • Total and Isoform-specific Quantitative Assessment of Circulating Fibulin-1 using Selected Reaction Monitoring MS and Time-resolved Immunofluorometry
    Overgaard et al., Proteomics Clin. Appl. (2014) - PMID: 25331251
  • Integrating Meta-Analysis of Microarray Data and Targeted Proteomics for Biomarker Identification: Application in Breast Cancer
    Pavlou et al., J. Proteome Res. (2014) - PMID: 24799281
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