Adaptive Diagnostics for the De-Novo-Detection of Viral Pathogens for Preventing Epidemics (DetektiVir)
New and reappearing viral pathogens represent a serious thread for human and animal health. Examples are the ZIKA-virus outbreak in South America or the variants of avian influenza emerging periodically. Since no diagnostic assays are available for new viruses, fast development of such assays is a key element to the detection, control and containment of outbreaks of pandemics and epidemics.
Aim of the project was the development of a modular generic diagnostic workflow starting from suspicious samples to a serological assay for virus evidence. The workflow was interconnected by a data management pipeline which allowed efficient data transfer between different functions as new generation sequencing, peptide libraries for the identification of serological markers and data from serological assays.
The project was funded by Bundesministerium für Bildung und Forschung (BMBF) and the program "Zivile Sicherheit – Schutz vor biologischen Gefahrenlagen und Pandemien"