Custom Peptide Libraries

Custom & High-Throughput Solutions for Medicinal Chemistry, Proteomics & Drug Discovery

At JPT Peptide Technologies, we specialize in peptide library synthesis with unmatched expertise and state-of-the-art automation. Whether you are studying protein interactions, drug discovery, immunotherapy, or proteomics, our custom and ready-to-use peptide libraries provide precise, reproducible, and high-quality results - at any scale.

Comprehensive Peptide Library Capabilities 

JPT supports a wide range of peptide libraries, from small-scale screening sets to ultra-large collections of up to 1 million peptides. Our expertise spans: 
  • Custom peptide libraries for drug discovery, immune monitoring, and structural analysis
  • Micro-scale to large-scale peptide synthesis, tailored to your research needs
  • Specialty libraries including macrocyclic peptides, biotinylated peptides, stapled peptides, and more
  • Advanced Fill & Finish solutions with automated compound management for seamless integration into your workflow
  • High-quality standards supported by LIMS-based quality management, batch reports, and production status tracking
  • Efficient global procurement with AEO-certified supply chain solutions for smooth access to unnatural amino acids and rare building blocks
  • In-house building block manufacturing, ensuring a reliable supply of custom peptide reagents
  • Flexible business contracts, including FTE contracts and fee-for-service agreements for pharmaceutical and biotech collaborations 

Our expert team is ready to help design, synthesize, and optimize peptide libraries that accelerate your research. 


What Are Peptide Libraries?

Peptide libraries are versatile collections of individual peptides, meticulously aliquoted and finished in various formats. These libraries can be designed from protein-spanning overlapping peptides, diverse structural sets, or any other peptide variations, making them invaluable tools for systematically studying biological properties. At JPT, we don’t just lead the market in peptide library synthesis; we also offer the broadest range of fill and finish formats, ensuring that you have the right tools for any application.


Explore Our Peptide Library Solutions

PepTrack™ Peptide Libraries

Our proprietary PepTrack™ Peptide Libraries are engineered specifically for cellular assays, such as T-cell assays. These peptide libraries are synthesized, purified, and analyzed to eliminate false-positive T-cell responses, prevent toxic inhibition, and extend peptide shelf life. With flexible specifications tailored to different applications, our customer support team is ready to help you choose the best peptide library specifications for your research.


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Medicinal Chemistry & Drug Discovery Peptide Libraries

Accelerate Small Molecule & Peptide Therapeutic Research
JPT’s peptide libraries for medicinal chemistry support lead discovery, structure-activity relationship (SAR) studies, and hit validation. Available Formats:
  • Macrocyclic peptides for constrained bioactive structures
  • Stapled peptides for improved stability and target binding
  • Biotinylated peptides for high-throughput screening assays
  • Libraries for kinase inhibitors, enzyme substrates, and ligand screening


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Proteomics Libraries & Kits

JPT offers the most extensive variety of proteomics reference peptides both customized and off-the shelf.

Our portfolio includes SIL peptides and absolute quantified peptides, peptide kits for control and standardization as well as a huge library of validated human reference peptides for mass-spectrometry-based proteomics. 


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BioTides Biotinylated Peptides

BioTides Biotinylated Peptides are designed for biomedical screening assays that require immobilization onto streptavidin coated beads, membranes, glass slides, or microtiter plates. They are synthesized in large numbers at unmatched pricing by high-throughput SPOT synthesis.


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PRISMA

PRISMA (Protein Interaction Screen on Peptide Matrix) is a tool to systematically explore cell signal transmission. Peptides are immobilized on a membrane that is incubated with a biological sample. Interacting proteins are then identified and quantified by mass spectrometry.


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ProteaseSpots

Protease Spots offer an efficient way to study protease activities and substrate specificities. Custom synthesized protease substrate peptides are immobilized on cellulose discs. The discs are delivered ready-to use in microtiter plates. During incubation with protease samples fluorescent detection can be performed at different time points.


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Protease Substrate Set

The most efficient way to study enzyme activity and substrate specificity is by incubating the enzyme of interest with multiple substrate peptides in parallel. Our ready-to-screen Substrate Set comprises of numerous substrate peptides, which were carefully selected from the UniProt database. 


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Why Choose JPT’s Peptide Libraries?


Automated Fill & Finish – Seamless Compound Management 
Our advanced Fill & Finish solutions ensure automated aliquoting, plating, and storage to streamline high-throughput screening. 
  • High-precision liquid handling for reproducible peptide aliquoting
  • Automated compound management for seamless integration into robotic workflows
  • Comprehensive batch and status reports to ensure full traceability 

Global Procurement & Building Block Manufacturing 
Custom Peptide Reagents & Smooth Supply Chain Solutions JPT ensures a reliable and efficient supply of specialty amino acids, unnatural building blocks, and custom reagents through our AEO-certified global procurement network.
  • Direct access to rare and unnatural amino acids
  • In-house synthesis of custom peptide building blocks
  • Regulatory-compliant procurement and shipping solutions

Flexible Business Models: FTE & Fee-for-Service Contracts 
We offer customized business contracts tailored to industry needs, including
  • Full-Time Equivalent (FTE) contracts for dedicated project support
  • Fee-for-service agreements for flexible peptide synthesis & analysis

Curious about how to create your own peptide library

Our team of experts is here to guide you through every step. From selecting the right peptide variations to choosing the perfect format, we’ll help you design a library that aligns perfectly with your research goals.

At JPT Peptide Technologies, we combine state-of-the-art laboratories with decades of expertise to deliver peptide libraries and synthesis services that are second to none. Discover how our custom peptide libraries can elevate your research and deliver the results you need. Learn more and request a quote today.

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