References with Clinical Peptides



  • A small CEACAM5 peptide restores the protective function of CD8+ regulatory T cells in Crohn’s disease
    Dunkin et al., Gastroenterology (2022) - PMID: 35700774
  • Rapid single-cell identification of EpsteinBarr virus-specific T-cell receptors for cellular therapy
    Lammoglia Cobo et al., Cytotherapy (2022) - 35525797
  • Reconstitution of EBV-directed T cell immunity by adoptive transfer of peptide-stimulated T cells in a patient after allogeneic stem cell transplantation for AITL
    Lammoglia Cobo et al., PLoS Pathogens (2022) - PMID: 35452490


  • Designing Personalized Antigen-Specific Immunotherapies for Autoimmune Diseases—The Case for Using Ignored Target Cell Antigen Determinants
    Tian et al., Cells (2022)
  • Generation of glucocorticoid-resistant SARS-CoV-2 T cells for adoptive cell therapy
    Basar et al., Cell Reports (2021)
  • Clinical effects of administering leukemia-specific donor T cells to patients with AML/MDS post-allogeneic transplant
    Lulla et al., Blood (2021)
  • Safety and Immunogenicity of an Inactivated Recombinant Newcastle Disease Virus Vaccine 2 Expressing SARS-CoV-2 Spike: Interim Results of a Randomised, Placebo-Controlled
    Pittisuttihum et al., MedRxiv (2021)
  • Combined PD-L1 and TIM-3 blockade improves the expansion of fit human CD8+ antigen-specific T cells for adoptive immunotherapy
    Lak et al., MedRxiv (2021)
  • T-Cell Therapy for Lymphoma Using Nonengineered Multiantigen-Targeted T Cells Is Safe and Produces Durable Clinical Effects
    Vasileiou et al., Journal of Clinical Oncology (2021) - PMID : 33507803
  • Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs
    Weingarten-Gabbay et al., Cell (2021) - PMID: 34171305


  • Preclinical Development and Clinical-Scale Manufacturing of HIV Gag-Specific, Lentivirus Modified CD4 T Cells for HIV Functional Cure
    Li et al., Molecular Therapy (2020)
  • Rapid generation of multivirus-specific T lymphocytes for the prevention and treatment of respiratory viral infections
    Vasileiou et al., Haematologica (2020) - PMID: 31004020
  • Virus-specific T-cell therapy to treat BK polyomavirus infection in bone marrow and solid organ transplant recipients
    Nelson et al., Blood Advances (2020)
  • The effects of β1 and β1+2 adrenergic receptor blockade on the exercise-induced mobilization and ex vivo expansion of virus-specific T cells: implications for cellular therapy and the anti-viral immune effects of exercise
    Kunz et al., Cell Stress and Chaperones (2020) - PMID: 32779001
  • HIV-Specific T Cells Can Be Generated against Non-escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform
    Patel et al., Molecular Therapy: Methods & Clinical Developement (2020)
  • Combined vaccination with NY-ESO-1 protein, poly-ICLC, and montanide improves humoral and cellular immune responses in high-risk melanoma patients
    Pavlick et al., Cancer Immunology Research (2020) - PMID : 31699709
  • Profiling HPV-16–specific T cell responses reveals broad antigen reactivities in oropharyngeal cancer patients
    Bhatt et al. Journal of Experimental Medicine (2020) - PMID: 32716518
  • An unbiased approach to defining bona fide cancer neoepitopes that elicit immune-mediated cancer rejection
    Brennick et al., Journal of Clinical Investigation (2020)
  • Autologous CMV-specific T cells are a safe adjuvant immunotherapy for primary glioblastoma multiforme
    Smith et al., Journal of Clinical Investigation (2020)
  • Peptide Pools For Target Antigen Identification, Immune Monitoring, and Cellular Therapy
    A.Castro et al., Cytotherapy (2020) - PMID: n.a.
  • “Mini” bank of only 8 donors supplies CMV-directed T cells to diverse recipients
    Tzannou et al., Blood Advances (2019) - PMID : 31481503
  • T-cell receptor sequencing demonstrates persistence of virus-specific T cells after antiviral immunotherapy
    Keller et al., British Journal of Haematology (2019) - PMID: 31219185
  • A non-functional neoepitope specific CD8+ T-cell response induced by tumor derived antigen exposure in vivo
    Vormehr et al., Oncoimmunology (2019)
  • Autologous adoptive T-cell therapy for recurrent or drug-resistant cytomegalovirus complications in solid organ transplant patients: A single-arm open-label phase I clinical trial
    Smith et al., Clinical Trial (2019) - PMID: 29982441
  • HIV-Specific, Ex Vivo Expanded T Cell Therapy: Feasibility, Safety, and Efficacy
    Sung et al., Molecular Therapy (2018)
  • Clinical and immunological responses after CD30-specific chimeric antigen receptor–redirected lymphocytes
    Ramos et al., Journal of Clinical Investigation (2017) - PMID: 28805662
  • Autologous Adoptive T-Cell Therapy for Recurrent or Drug-Resistant Cytomegalovirus Complications in Solid Organ Transplant Patients: A Single-Arm Open-Label Phase I Clinical Trial
    Smith et al., Infectious Diseases Society of America (2016) - PMID: 29982441
  • Human Parainfluenza Virus-3 Can be Targeted by Rapidly Ex Vivo Expanded T Lymphocytes
    McLaughlin et al., Cytotherapy (2016) - PMID: 27692559
  • Peptide‐Stimulated Expansion of Virus‐Specific T Cells for Preventative Treatment After Allogeneic Stem Cell Transplantation
    Gary et al., AppNote (2015) - PMID: n.a.
  • Broadly-Specific Cytotoxic T Cells Targeting Multiple HIV Antigens Are Expanded From HIV+ Patients: Implications for Immunotherapy
    Lam et al., Molecular Therapy (2015) - PMID: 25366030
  • Expanded Cytotoxic T-Cell Lymphocytes Target the Latent HIV Reservoir
    Sung et al., Journal of Infectious Diseases (2015) - PMID: 25589335
  • Ex vivo Expansion of Human T cells for Adoptive Immunotherapy Using the Novel Xeno-free CTS Immune Cell Serum Replacement
    Smith et al., Clinical & Translational Immunology (2015) - PMID: 25671129
  • PepMixes to Generate Multiviral CTLS with Broad Specificity
    Leen et al., US Patent 20,150,010,519 (2015)
  • Complete Remission Following Decitabine/Dendritic Cell Vaccine for Relapsed Neuroblastoma
    Krishnadas et al., Pediatrics. (2013) - PMID: 23266925
  • QIMR Berghofer Medical Research Institute Selects JPT’s GxP PepMix™ Peptide Pool Technology to Support its Phase I/II Clinical Trials of Adoptive Immunotherapy for Human Cytomegalovirus-associated Diseases
    Press Release (2014)
  • Activity of Broad-Spectrum T Cells as Treatment for AdV, EBV, CMV, BKV, and HHV6 Infections After HSCT
    Papadopoulou et al., Sci Transl Med. (2014) - PMID: 24964991
  • Immunotherapeutic Strategies to Prevent and Treat Human Herpesvirus 6 Reactivation after Allogeneic Stem Cell Transplantation
    Gerdemann et al. (2013) - PMID: 23152545
  • Rapidly Generated Multivirus-specific Cytotoxic T lymphocytes for the Prophylaxis and Treatment of Viral Infections
    Gerdemann et al., Mol Ther. (2012) - PMID: 22801446
  • LMP-Specific T-Cells for Patients With Relapsed EBV-Positive Lymphoma (ALCI)
    Bollard et al. (2012) - PMID: n.a
  • Cytotoxic T Lymphocytes Simultaneously Targeting Multiple Tumor-associated Antigens to Treat EBV Negative Lymphoma
    Gerdemann et al., Molecular Therapy (2011) - PMID: 21915103
  • Cytotoxic T Lymphocyte Therapy with Donor T Cells Prevents and Treats Adenovirus and Epstein-Barr Virus Infections after Haploidentical and Matched Unrelated Stem Cell Transplantation
    Leen et al., Blood (2009) - PMID: 19700662

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