A small CEACAM5 peptide restores the protective function of CD8+ regulatory T cells in Crohn’s disease Dunkin et al., Gastroenterology (2022) - PMID: 35700774
Rapid single-cell identification of EpsteinBarr virus-specific T-cell receptors for cellular therapy Lammoglia Cobo et al., Cytotherapy (2022) - 35525797
Reconstitution of EBV-directed T cell immunity by adoptive transfer of peptide-stimulated T cells in a patient after allogeneic stem cell transplantation for AITL Lammoglia Cobo et al., PLoS Pathogens (2022) - PMID: 35452490
2021
2021
Designing Personalized Antigen-Specific Immunotherapies for Autoimmune Diseases—The Case for Using Ignored Target Cell Antigen Determinants Tian et al., Cells (2022)
Generation of glucocorticoid-resistant SARS-CoV-2 T cells for adoptive cell therapy Basar et al., Cell Reports (2021)
Clinical effects of administering leukemia-specific donor T cells to patients with AML/MDS post-allogeneic transplant Lulla et al., Blood (2021)
Safety and Immunogenicity of an Inactivated Recombinant Newcastle Disease Virus Vaccine 2 Expressing SARS-CoV-2 Spike: Interim Results of a Randomised, Placebo-Controlled Pittisuttihum et al., MedRxiv (2021)
Combined PD-L1 and TIM-3 blockade improves the expansion of fit human CD8+ antigen-specific T cells for adoptive immunotherapy Lak et al., MedRxiv (2021)
T-Cell Therapy for Lymphoma Using Nonengineered Multiantigen-Targeted T Cells Is Safe and Produces Durable Clinical Effects Vasileiou et al., Journal of Clinical Oncology (2021) - PMID : 33507803
Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs Weingarten-Gabbay et al., Cell (2021) - PMID: 34171305
Archive
Archive
Preclinical Development and Clinical-Scale Manufacturing of HIV Gag-Specific, Lentivirus Modified CD4 T Cells for HIV Functional Cure Li et al., Molecular Therapy (2020)
Rapid generation of multivirus-specific T lymphocytes for the prevention and treatment of respiratory viral infections Vasileiou et al., Haematologica (2020) - PMID: 31004020
Virus-specific T-cell therapy to treat BK polyomavirus infection in bone marrow and solid organ transplant recipients Nelson et al., Blood Advances (2020)
The effects of β1 and β1+2 adrenergic receptor blockade on the exercise-induced mobilization and ex vivo expansion of virus-specific T cells: implications for cellular therapy and the anti-viral immune effects of exercise Kunz et al., Cell Stress and Chaperones (2020) - PMID: 32779001
HIV-Specific T Cells Can Be Generated against Non-escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform Patel et al., Molecular Therapy: Methods & Clinical Developement (2020)
Combined vaccination with NY-ESO-1 protein, poly-ICLC, and montanide improves humoral and cellular immune responses in high-risk melanoma patients Pavlick et al., Cancer Immunology Research (2020) - PMID : 31699709
Profiling HPV-16–specific T cell responses reveals broad antigen reactivities in oropharyngeal cancer patients Bhatt et al. Journal of Experimental Medicine (2020) - PMID: 32716518
An unbiased approach to defining bona fide cancer neoepitopes that elicit immune-mediated cancer rejection Brennick et al., Journal of Clinical Investigation (2020)
Autologous CMV-specific T cells are a safe adjuvant immunotherapy for primary glioblastoma multiforme Smith et al., Journal of Clinical Investigation (2020)
Peptide Pools For Target Antigen Identification, Immune Monitoring, and Cellular Therapy A.Castro et al., Cytotherapy (2020) - PMID: n.a.
“Mini” bank of only 8 donors supplies CMV-directed T cells to diverse recipients Tzannou et al., Blood Advances (2019) - PMID : 31481503
T-cell receptor sequencing demonstrates persistence of virus-specific T cells after antiviral immunotherapy Keller et al., British Journal of Haematology (2019) - PMID: 31219185
A non-functional neoepitope specific CD8+ T-cell response induced by tumor derived antigen exposure in vivo Vormehr et al., Oncoimmunology (2019)
Autologous adoptive T-cell therapy for recurrent or drug-resistant cytomegalovirus complications in solid organ transplant patients: A single-arm open-label phase I clinical trial Smith et al., Clinical Trial (2019) - PMID: 29982441
HIV-Specific, Ex Vivo Expanded T Cell Therapy: Feasibility, Safety, and Efficacy Sung et al., Molecular Therapy (2018)
Clinical and immunological responses after CD30-specific chimeric antigen receptor–redirected lymphocytes Ramos et al., Journal of Clinical Investigation (2017) - PMID: 28805662
Autologous Adoptive T-Cell Therapy for Recurrent or Drug-Resistant Cytomegalovirus Complications in Solid Organ Transplant Patients: A Single-Arm Open-Label Phase I Clinical Trial Smith et al., Infectious Diseases Society of America (2016) - PMID: 29982441
Human Parainfluenza Virus-3 Can be Targeted by Rapidly Ex Vivo Expanded T Lymphocytes McLaughlin et al., Cytotherapy (2016) - PMID: 27692559
Peptide‐Stimulated Expansion of Virus‐Specific T Cells for Preventative Treatment After Allogeneic Stem Cell Transplantation Gary et al., AppNote (2015) - PMID: n.a.
Broadly-Specific Cytotoxic T Cells Targeting Multiple HIV Antigens Are Expanded From HIV+ Patients: Implications for Immunotherapy Lam et al., Molecular Therapy (2015) - PMID: 25366030
Expanded Cytotoxic T-Cell Lymphocytes Target the Latent HIV Reservoir Sung et al., Journal of Infectious Diseases (2015) - PMID: 25589335
Ex vivo Expansion of Human T cells for Adoptive Immunotherapy Using the Novel Xeno-free CTS Immune Cell Serum Replacement Smith et al., Clinical & Translational Immunology (2015) - PMID: 25671129
PepMixes to Generate Multiviral CTLS with Broad Specificity Leen et al., US Patent 20,150,010,519 (2015)
Complete Remission Following Decitabine/Dendritic Cell Vaccine for Relapsed Neuroblastoma Krishnadas et al., Pediatrics. (2013) - PMID: 23266925
QIMR Berghofer Medical Research Institute Selects JPT’s GxP PepMix™ Peptide Pool Technology to Support its Phase I/II Clinical Trials of Adoptive Immunotherapy for Human Cytomegalovirus-associated Diseases Press Release (2014)
Activity of Broad-Spectrum T Cells as Treatment for AdV, EBV, CMV, BKV, and HHV6 Infections After HSCT Papadopoulou et al., Sci Transl Med. (2014) - PMID: 24964991
Immunotherapeutic Strategies to Prevent and Treat Human Herpesvirus 6 Reactivation after Allogeneic Stem Cell Transplantation Gerdemann et al. (2013) - PMID: 23152545
Rapidly Generated Multivirus-specific Cytotoxic T lymphocytes for the Prophylaxis and Treatment of Viral Infections Gerdemann et al., Mol Ther. (2012) - PMID: 22801446
LMP-Specific T-Cells for Patients With Relapsed EBV-Positive Lymphoma (ALCI) Bollard et al. (2012) - PMID: n.a
Cytotoxic T Lymphocytes Simultaneously Targeting Multiple Tumor-associated Antigens to Treat EBV Negative Lymphoma Gerdemann et al., Molecular Therapy (2011) - PMID: 21915103
Cytotoxic T Lymphocyte Therapy with Donor T Cells Prevents and Treats Adenovirus and Epstein-Barr Virus Infections after Haploidentical and Matched Unrelated Stem Cell Transplantation Leen et al., Blood (2009) - PMID: 19700662
