At JPT, we pride ourselves on our extensive expertise in custom peptide synthesis. Our commitment to delivering the highest-quality custom peptides, regardless of sequence complexity, sets us apart. Request a quote to receive a competitive price. If you need a reliable, high-quality peptide synthesis service with regulated processes, look no further than JPT. Order custom peptides tailored to your specifications, including modifications, quantities, and formats!
Why Choose JPT’s Custom Peptide Synthesis Service
With over 20 years of experience, we synthesize more than 1 million peptides annually, achieving a success rate exceeding 99%. We customize each peptide specification to perfectly fit your application. Here’s what makes our custom peptide synthesis services exceptional:
- Unparalleled capacity for synthesizing peptides of any complexity
- ISO 9001:2015-certified quality management system
- Clinical Peptide and Pool synthesis to meet diverse needs
- Dedicated production labs for synthesis and purification
- Advanced solid-phase peptide synthesis (SPPS) technology
- Strict compliance with environmental, health, and ethical standards
- State-of-the-art equipment and highly trained staff
- Expert customer support for peptide applications
- Scalable Peptide Solutions from micro to large scale
- Competitive custom peptide synthesis price
Quality Control in Custom Peptide Synthesis
Quality control is a cornerstone of our custom peptide synthesis process. After synthesis of peptides, each peptide undergoes routine analysis by LC-MS, MALDI-MS, or HPLC to confirm its identity and peptide purity. JPT provides a thorough analytical data sheet and corresponding raw data documentation with each order. All documentation is meticulously double-checked and archived before leaving our facility. Our standard quality control includes LC-MS with ion trap, quadrupole, or TOF detection, MALDI-MS, or HPLC. We also offer a variety of optional Peptide Analysis Services, including Stability Testing, Peptide Content Determination, and Cell Toxicity Testing:
- Amino acid analysis (AAA)
- Peptide sequence analysis via mass spectrometry
- Residual solvent and water determination
- Solubility and stability testing
- Toxicity, sterility, endotoxin, and bioburden testing
- NMR (nuclear magnetic resonance)
- And many more!
Modifications and Labels for Custom Peptide Synthesis
JPT also excels in the design and production of custom peptides with various modifications, such as fluorescent labels, biotinylation, alkylation, glycosylation, phosphorylation, and more. These modifications improve peptide functionality and stability, broadening their applications in research and medicine.
Our customization options include:
- Unnatural & unusual amino acids
- Isotope-labeled peptides
- Macrocyclic peptides and post-translational modifications
- Fluorescent & FRET peptides
- Biotinylated & tagged peptides
- Long, cyclic, or dimeric peptides
- Various linkers, spacers, & PEGs
- Protein conjugates & immunogenic peptides
- Peptide pooling and library services
For detailed information on the custom peptide synthesis of modified peptides, please visit our Peptide Modifications & Specialty Peptides and Post-translational Modifications pages. Contact us or send us a quote request for modified custom synthesis price.
Advantages of Custom Peptides over Whole Proteins
- High-batch-to-batch reproducibility
- Reliable quality control for peptide pool generation
- Extended shelf stability when stored lyophilized
- Cost-effective compared to whole proteins
- Enhanced T-cell stimulation and natural ligand mimicry
- Precise targeting with custom peptides
- Flexibility to add modifications, labels, and tags
The Science Behind Custom Peptide Synthesis
Peptide synthesis involves the creation of peptides by sequentially adding amino acids to a growing chain. This process can be performed using either solid-phase peptide synthesis (SPPS) or liquid-phase peptide synthesis (LPPS). SPPS, developed by Robert Bruce Merrifield, is the most commonly used method due to its efficiency and versatility. JPT adds an additional step, called capping, after each amino acid coupling. Capping prevents side reactions and deletion sequences, which can lead to false positive results. For more information, please watch our capping video:
In addition to classic solid phase custom peptide synthesis, JPT uses SPOT synthesis, which allows the synthesis of hundreds of micro scale peptides in parallel. The resulting high-throughput peptides are fast and have the lowest custom peptide synthesis prices on the market.
Request a Quote Today!
At JPT, we are committed to supporting your research and clinical needs with our custom peptide synthesis services. Our team of experts is ready to assist you with any inquiries or orders. Contact us today to find out how our custom synthesis can enhance your research projects and clinical applications.
Modifications & Labels for Custom Peptide Synthesis
- Unnatural & unusual amino acids
- Isotope-labeled peptides
- Macrocyclic peptides
- Post-translational modifications
- Fluorescent & FRET peptides
- Biotinylated & tagged peptides
- Long, cyclic or dimeric peptides
- Different linkers, spacers & PEGs
- Protein conjugates & immunogenic peptides
- Peptidomimetics
- Peptide pooling and library service
