JPT’s Medicinal Chemistry unit has long standing experience from discovery to preclinical development projects. The team members have been critically involved in several peptide and small molecule hit-to-lead qualification and peptide optimization projects.
Medicinal Chemistry at JPT is supported by an extraordinarily high capacity in peptide chemistry, automated synthesis, analytics and purification. By using solid as well as solution phase chemistry, JPT is able to synthesize as many as 50 000 crude and several hundred purified peptides per week.
JPT is in possession of an extensive collection of building blocks and routinely does many types of peptide modifications and conjugations. Besides that, JPT has collected a significant know-how in conformational stabilization and size reduction of peptides, which is used to optimize compounds to finally meet the predefined target product profile.