Ultra High-Throughput Synthesis

JPT Peptide Technologies has the unique ability to produce complex micro-scale peptides libraries made of up to 1 million single, individual peptides with rapid turnaround at unmatched pricing. Our patented SPOT technology allows for the synthesis of thousands of peptides on membrane supports. The resulting individual peptides are then transferred into microtiter plates and lyophilized.

Product Specifications:
  • Amounts of 50-250 nmol per peptide
  • Peptide length: 6-20mers
  • C-terminal acid or amide
  • Non-natural and isotopically labeled amino acids
  • Ready-to-use peptides in 96/384-well plates
  • Patented high-throughput SPOT-technology
  • Full analysis (LC-MS, MALDI) available

Applications

Applications

  • Screening projects for: bioactive peptides, T-cell epitopes, peptidic ligands, substrates, proteotypic peptides and more
  • Hit to lead qualification of peptidic and peptidomimetic structures
  • Systematic high-throughput optimization of peptidic compounds
  • Proteome spanning biomarker discovery
  • Peptide microarray production
  • Development of peptide pools for immune monitoring
  • GPCR deorphanization
Benefits

Benefits

  • High content screening
  • Quick turnaround at discovery and optimization cycles
  • Low cost per data point
References

References

  • IgE Epitope Mapping Using Peptide Microarray Immunoassay
    Gimenez et al., Methods Mol Biol. (2016) - PMID: 26490481
  • Molecular Diagnosis of Shrimp Allergy: Efficiency of Several Allergens to Predict Clinical Reactivity
    Pascal et al., J Allergy Clin Immunol Pract. (2015) - PMID: 25769902
  • Protein Energy Malnutrition during Vaccination Has Limited Influence on Vaccine Efficacy but Abolishes Immunity if Administered during Mycobacterium tuberculosis Infection
    Hoang et al., Infect. Immun. (2015) - PMID: 25754202
  • Synergistic Inhibition of PARP-1 and NF-κB Signaling Down-regulates Immune Response Against Recombinant AAV2 Vectors During Hepatic Gene Therapy
    Hareendran et al., Eur J Immunol. (2015) - PMID: 26443873
  • The Active site of O-GlcNAc Transferase Imposes Constraints on Substrate Sequence
    Pathak et al., Nat Struct Mol Biol. (2015) - PMID: 26237509
  • Protein Abundance Changes and Ubiquitylation Targets Identified After Inhibition of the Proteasome with Syringolin A
    Svozil et al., Molecular et Cellular Proteomics (2014) - PMID: 24732913
  • Food Peptidomics: Large Scale Analysis of Small Bioactive Peptides - A Pilot Study
    Lahrichi et al., Journal of Proteomics (2013) - PMID: 23500135
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