Discover our PepMix™ Human (Melan-A/MART-1), a carefully curated peptide pool designed for advanced research in T-cell immunity and cancer biomarker studies. This peptide mix comprises 27 distinct peptides derived from the Melanoma Antigen Recognized by T-cells 1 (MART-1), also known as Melan-A. MART-1 is a pivotal target in melanoma immunology, making this pool essential for researchers focused on melanoma and related cancers.
Pool of 27 peptides derived from a peptide scan through Melanoma antigen recognized by T-cells 1 (MART-1) (Swiss-Prot ID: Q16655) of Human.
PepMix™ Human (Melan-A/MART-1) - Specifications
Amount: 25 µg (approx. 15 nmol) / peptide (for stimulation of up to 2,5 x 10
8 cells)
Purity: Development Grade: each peptide purified to > 70% (HPLC/MS)
(equivalent to an average purity of 85%)
Delivery Format: Freeze-dried in glass vial
Application(s): T-cell Immunity, Cancer biomarker research
Condition(s)/Topic(s): Cancer, Melanoma
Standard Delivery Time: 2-5 days
Detailed Features of PepMix™ Human (Melan-A/MART-1)
High-Purity Peptides for Accurate Research
Each peptide in the PepMix™ Human (Melan-A/MART-1) pool is purified to development grade with a minimum purity of 70% (HPLC/MS), averaging 85% purity. This high standard ensures that your research results are reliable and reproducible, allowing for precise stimulation and analysis of T-cell responses.
Optimal Quantity for Extensive Research
The pool contains 25 µg (approximately 15 nmol) of each peptide, providing ample material to stimulate up to 2.5 x 108 cells. This quantity is ideal for extensive experimental setups and high-throughput studies, making it suitable for various research applications.
Convenient and Reliable Delivery
The peptides are delivered freeze-dried in a glass vial, which maintains stability and extends shelf life. This format is perfect for long-term storage and ease of use in laboratory settings.
Applications of PepMix™ Human (Melan-A/MART-1)
T-Cell Immunity Studies
MART-1 peptides are instrumental in studying T-cell responses against melanoma cells. The PepMix™ pool enables researchers to explore the effectiveness of potential immunotherapies and understand the immune system's interaction with melanoma antigens.
Cancer Biomarker Research
By using this peptide pool, scientists can investigate the role of Melan-A/MART-1 as a cancer biomarker. It supports research into identifying new biomarkers for melanoma and evaluating their potential in clinical applications.
Research Topics and Conditions
Focus on Melanoma
The PepMix™ Human (Melan-A/MART-1) is specifically designed to address melanoma, a serious skin cancer. It provides valuable insights into the antigenic targets of melanoma, facilitating advancements in targeted therapies.
Customizing Your Peptide Pool
If you require a personalized peptide pool, we offer customization options. You can choose specific peptide sequences, adjust the amount, select the desired purity, and decide on the format that best suits your research needs. Our team is available to guide you through the customization process and ensure your specifications are met.
PepMix™ Peptide Pools
Protein-spanning mixtures of overlapping peptides (PepMix™) are extremely efficient for
- Antigen-specific T cell stimulation in T cell assays (e.g. in ELISpot, ICS, cell-mediated cytotoxicity or proliferation assays)
- In-vitro T cell expansion
- Dendritic cell pulsing
- Immune monitoring
- Cellular immune response profiling
- T cell epitope identification
- Standardization of T cell assays
Benefits of PepMix™
- Each peptide quality controlled and guaranteed for identity and purity
- CoA and HPLC-MS data available
- High batch-to-batch consistency
- No false positive T cell responses by contaminating deletion peptides
- No toxic inhibition of T cell responses due to stringent purification of each peptide
- Minimization of endotoxin contamination due to low bioburden process
- ADCF policy in place
- HLA independent stimulation (with antigen spanning peptide pools)
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