Methylated Peptides


Peptide Methylation

  • Occurs at arginine or lysine residues, resulting in methylarginine or methyllysine
  • Is an important post-translational modification of proteins
  • For the synthesis of methylated peptides several methyl groups can be transferred to arginine or lysine (see figures)
  • JPT can provide all of the mono-, di- and tri-methylated Arg and Lys analogs listed

Methylated Proteins

  • Are involved in the regulation of several cellular functions, e.g. transcription and cell division
  • Prominent example: Methylation and demethylation of histones in epigenetic regulation, influencing the availability of DNA for transcription

Please also have a look at our PTM Reference & Kits for direct usage as reference material in mass-spectrometry based proteomics to support PTM proteomics.


Arginine Methylations

PTM arginine methylations modification
PTM arginine methylations modification
PTM arginine methylations modification
Lysine Methylations
PTM lysine methylations modifications
PTM lysine methylations modifications
PTM lysine methylations modifications