Welcome to BioTides - Low-Cost Biotinylated Peptides
Published on 05/04/2023
Because of its high affinity and binding specificity, the interaction of biotin-streptavidin (or biotin-avidin) is used for immunoassays and other assays to immobilize, label, detect and purify peptides. Therefore, biotinylation of peptides is an efficient and well-established method to bind peptides to streptavidin-coated surfaces such as ELISA plates, beads, membranes or columns.
However, classical synthesis of biotinylated peptides can be quite expensive, especially if you need many peptides for screening and discovery. Therefore, we developed our BioTides, biotinylated peptides synthesized by our proprietary SPOT method!
What are BioTides?
- BioTinylated at N-terminus
- Flexible linker/spacer to avoid sterical hindrance
- High-throughput SPOT synthesis allows for unmatched prices & fast delivery
- Quality and high purity is ensured by capping steps during synthesis
- BioTides provide equal performance compared to peptides synthesized by conventional methods but at much lower cost
- Visit the BioTides product page or contact us for questions and pricing!
- Peptide ELISA for mapping of protein/protein interaction sites
- Precipitation of interacting proteins
- Production of peptide microarrays
- Loading of columns for affinity chromatography
- Identification and optimization of enzyme substrates via standard screening systems
- Read our Application Note: BioTides™ as High Throughput Screening Tool for the Identification of Antibody Binding Sites
- Tumor microenvironment mimicking 3D models unveil the multifaceted effects of SMAC mimetics
Pinto et al., iScience (2023) - PMID: 37009211
- Antibody landscape of C57BL/6 mice cured of B78 melanoma via immunotherapy
Hoefges et al., BioRxiv (2023) - PMID: 36896021
- Functional Analysis of Human and Feline Coronavirus Cross-Reactive Antibodies Directed Against the SARS-CoV-2 Fusion Peptide
Vanderheijden et al., Frontiers in Immunology (2022) - PMID: 35069571
- Neutralizing Monoclonal Anti-SARS-CoV-2 Antibodies Isolated from Immunized Rabbits Define Novel Vulnerable Spike-Protein Epitope
Efi Makdasi et al., Viruses (2021) - PMID: 33810465
Gwendolyn Swarbrick, PhD, OHSU, Portland, USA