Let our Antibody Profiling Assays Work for You!
Published on 22/03/2022
Antibody response plays an important role in protection following an infection, vaccination, or immunotherapy. Reliable serological monitoring over time is instrumental in determining the success of therapies, gaining insight into seroprevalence in populations, and in learning more about a disease.
Profiling antibody responses using peptide microarrays has been shown to be a powerful approach for epitope-resolved identification of selective antibody binders within antigens or even whole proteomes.
JPT is the market leader for high-quality peptide microarrays, both as off-the shelf and tailored PepStar microarrays as well as corresponding antibody assay services !
Applications:
- Antibody response profiling
- Biomarker discovery
- Serological test development
- Antibody epitope mapping
- Validation of protein interactions
- Immune monitoring
What are the benefits of selecting our modular assay services?
- In comparison to protein microarrays, peptide microarrays avoid metabolic or enzymatic interference
- Compatible with antibodies, lysates, serum or other patient samples
- Flexible microarray format and peptide design provide optimized experimental setup for each project
- Sample handling and profiling in an environment regulated by DIN ISO 9001:2015
- Strong bioinformatic support for microarray design and data analysis
Discuss your research questions with us! Our Customer Support will help you along the way from selecting the optimal research strategy, discussing the experimental setup, to data evaluation.
Many labs have already used JPT peptide microarrays and published their results. Have a look at our list of selected references for PepStar Peptide Microarrays and PepSpots - Peptides on Cellulose:
- Broadly binding and functional antibodies and persisting memory B cells elicited by HIV vaccine PDPHV
Wang et al., NPJ Vaccines (2022) – PMID: 35140230 - SARS-CoV-2 mRNA vaccination fails to elicit humoral and cellular immune responses in multiple sclerosis patients receiving fingolimod
Meyer-Arndt et al., MedRxiv (2022) - Use of Peptide Microarrays for Fast and Informative Profiling of Therapeutic Antibody Formulation Conditions
James Austerberry et al., Mol Pharm, (2021) – PMID: 34658237 - Peptide Microarray-Based Analysis of Antibody Responses to SARS-CoV-2 Identifies Unique Epitopes With Potential for Diagnostic Test Development
Pavlo Holenya et al., Eur J Immunol. (2021) - PMID: 33772767 - Profiling the HCV Immune Response in Patients With Chronic Liver Diseases and Hepatocellular Carcinoma by Peptide Microarray Analysis
Anna Lucia Tornesello et al., Curr Med Chem, (2021) – PMID: 34736375 - Identification of Key Biomarkers in Bladder Cancer: Evidence from a Bioinformatics Analysis
Chuan Zhang et al., Diagnostics (2020) - PMID: 31991631 - Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone Analysis
Pavlo Lutsik et al., Nat Commun (2020) – PMID: 33110075