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Identify Epitope-resolved Antibody Responses with Peptide Microarrays

Published on 25/01/2022

Antibody response to SARS-CoV-2 plays an important role in protection against COVID-19. Therefore, reliable serological monitoring is instrumental in determining the success of vaccination, in gaining insight into seroprevalence in populations, and in learning more about the disease.

In a recent publication, using JPT’s PepStar™ Antigen Collection Pan-Coronavirus peptide microarray which displays the complete SARS-CoV-2 proteome as well as relevant common cold corona virus antigens, a widespread cross-reactivity was detected in several immunodominant antigen regions. Importantly, using combinations of selected peptides, a statistically significant discrimination between COVID-19 patients and controls could be achieved, allowing the selection of dedicated peptides for further development of peptide based assays.
Please have a look at our PepStar™ peptide microarrays for a large variety of infectious disease and tumor associated antigens, and the accompanying peptide microarray assay services!
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