The Urodilatin, Human (ANP 95-126) is a high quality natriuretic peptide for cardiovascular research. Urodilatin is a renal natriuretic peptide derived from the same precursor as atrial natriuretic peptide in kidney tubular cells and secreted luminally. Urodilatin regulates sodium and water reabsorption in the kidney. While it is not normally found in the circulation, systemic administration of urodilatin has pharmacological effects on renal, cardiovascular, and pulmonary parameters in animals. The Urodilatin, Human (ANP 95-126), H-TAPRSLRRSSCFGGRMDRIGAQSGLGCNSFRY-OH (C11-C27 disulfide bond) from JPT is produced under strict quality management.
Urodilatin, Human (ANP 95-126) - Specifications
- Peptide sequence: H-TAPRSLRRSSCFGGRMDRIGAQSGLGCNSFRY-OH (C11-C27 disulfide bond)
- Amount: 0.5 mg
- Purity: >95% (HPLC/MS)
- Counterion: TFA
- Delivery Format: Freeze-dried in plastic vial
- Application(s): Cardiovascular Research
- Condition(s)/Topic(s): Electrolyte balance, cardiovascular disease
- Standard Delivery Time: approx. 3 weeks
Are you interested in other natriuretic peptides?Choose sequence, amount and purity. We will assist you along the way: Custom Peptide Synthesis
Natriuretic Peptides from JPT
Natriuretic peptides are peptide hormones that regulate the cardiovascular system. Natriuretic peptides display strong diuretic, natriuretic, and vasodilatory effects. These peptide hormones are regulating blood pressure, fluid-electrolyte balance, and cardiovascular function and are involved in inflammation, and apoptosis. As they are activated during heart failure, a major clinical application of natriuretic peptides is diagnosing heart failure.
There are five types of natriuretic peptides:
- Atrial natriuretic peptide (ANP)
- Brain natriuretic peptide (BNP)
- C-type natriuretic peptide (CNP)
- Urodilatin (URO)
- Dendroaspis natriuretic peptide (DNP)
Benefits of JPT’s Natriuretic Peptides
- Each peptide quality controlled and guaranteed for identity and purity
- CoA and HPLC-MS data available
- High batch-to-batch consistency
- Synthesis protocols designed to avoid toxic contaminants and side products
- Provision of freeze dried aliquots for enhanced stability
- Proven track record for applications in clinical studies