A truncation library is used to
- Determine the minimum length of an epitope (minimal epitope)
- Map the minimal binding site of a protein that is required for proper binding
Truncation libraries are generated by reducing the peptide length (truncation) amino acid per amino acid from each terminus creating a set of truncated peptides with different lengths. If the key residues have already been identified using an alanine scanning library , truncation can be stopped at the key residues position.
Use our free and easy-to-use PepSequencer for generation of truncation libraries!
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