Cyclization Library

Peptide cyclization libraries consisting of cyclic peptides (cyclized peptides) are used for

  • Development of peptides with enhanced bio stability
  • Mimicking secondary protein structures (e.g. protein loops)
  • Optimizing peptides (e.g. peptide ligands with increased binding potency/selectivity and enhanced protease stability)

For a cyclization library cyclic peptides can be synthesized by different methods, e.g. head-to-tail cyclization, side-chain-to-side-chain, head-to-side-chain, and side-chain-to-tail cyclization.

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use of cyclization library
use of cyclization library
use of cyclization library

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