SPT-His-TQL-hum-10pm

SpikeTides™ Set Histone heavy quantified - 10 pmol

US$1,800.00

Description

Product Description

Collection of 37stable isotope-labeled and absolutely quantified proteotypic peptides for Histone H3 for direct usage in mass-spectrometry based proteomics (MRM). The set comprises wild-type peptides and their Lys(Ac), Lys(Me), Lys(Me2) and Lys(Me3) modifications
Amount: 10 pmol/peptide
Purity: crude
Delivery Format: Freeze-dried in 1 x 96 tube rack
Application(s): Mass spectrometry
Indication(s)/Topic(s): Acetyltransferase, Cancer, Epigenetics, Kinase, Phosphatase
Delivery Time: approx. 10 days

JPT's heavy labeled and quantified SpikeTides™ Sets
JPT produced a set of stable isotope labeled proteotypic peptides for post-translationally modified histone H3 peptides. The peptides of this set are absolutely quantified for usage as internal standards in mass spectrometry assays.

Benefits of JPT's heavy labeled & quantified SpikeTides™ Sets
- Absolute quantification of multiple proteins from a single sample
- First economic absolutely quantified peptide set available
- Multiplexed analysis of disease status and therapeutic success

References

References for SpikeTides™ Set Histone heavy quantified - 10 pmol

References:
Read References with Histone Code Tools

Application Note
Absolute Quantification of Metabolic Enzymes via Targeted Proteomics using a new Kit of SpikeTides™ Peptides
Bindel et al., Application Note (2015) Full text

Testimonials
"My unit at the Banting and Best Department of Medical Research, University of Toronto Centre for Cellular and Biomolecular Research (CCBR) works on the systematic identification and quantification of proteins and protein complexes on a global level. In addition we have started to perform targeted proteomics to study protein regulation within pathways, e.g. signaling pathways during stem cell fate decision. For this we used JPT's various SpikeTides™ peptide products to build LC-MRM assays in a fast and cost efficient manner. More recently we also found new ways of using low cost SpikeTides™_TQL as quantitative peptide standards in order to quantify protein targets more accurately. We are currently in the process of validating this technology for the accurate quantification of various predicted microRNA targets."
Prof. Andrew Emili, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto

"My group studies the proteomic composition of distinct chromatin domains, the mechanisms that operate to maintain the composition of histone modifications and the associated proteins. For precise and accurate identification and quantification of histone peptides that carry multiple post-translational modifications directly from biological samples JPT's SpikeTides™ _TQL peptide standards proved to be of excellent value for our research in various projects."
Prof. Dr. Axel Imhof, Adolf-Butenandt Institute, University of Munich, Germany

Documentation

Documentation for SpikeTides™ Set Histone heavy quantified - 10 pmol

Properties

Properties of SpikeTides™ Set Histone heavy quantified - 10 pmol

Properties Values
Application: Mass spectrometry
Category: Absolute Quantified Peptides -SpikeTides™ TQL
Indication / Topic: Acetyltransferase, Cancer, Epigenetics, Phosphatase
Organism: Homo sapiens (Human)
Protein Name: Histones, Kinase
amount: 1000 pmol/peptide

Further Information to SpikeTides™ Set Histone heavy quantified - 10 pmol

Information Values
Sequence: See Product Documentation
Specifications: Absolutely quantified proteotypic stable isotope-labeled peptides with Qtag
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Quality Assurance

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