SP-MHCI-SCR-2
We can produce the scrambled peptide for all our antigen peptides and other peptide sequences. The scrambled peptide versions are cross-checked against the Uniprot database (https://www.uniprot.org/) to ensure that the scrambled sequence does not correspond to any natural sequence. Additionally, MHC binding predictions are used to screen against the most common HLA types (HLA-A01:01, HLA-A02:01, HLA-A03:01, HLA-A24:02, HLA-B*07:02). Only peptides that exceed an affinity threshold of 500 nM, which is routinely used for peptide selection (https://pmc.ncbi.nlm.nih.gov/articles/PMC3872965/), are chosen.
Scrambled Peptides are high quality epitope peptides for stimulation of antigen-specific T cells in T cell assays such as ELISPOT, ICS, cytotoxicity or proliferation assays.
Do you need a scrambled version of this antigen peptide?We can produce scrambled versions for all our antigen peptides and other peptide sequences. These scrambled peptide versions are cross-checked against the Uniprot database to ensure that the scrambled sequence does not correspond to any natural sequence. Have a look at Scrambled Antigen Peptides!
Are you interested in other antigen peptides?Choose sequence, amount and purity. We will assist you along the way: Custom Peptide Synthesis
JPT’s Antigen Peptides
Find your antigen peptide and select the connected PepMix™ Peptide Pool and MHC Multimer for efficient immune monitoring, mapping of T cell epitopes or development of immunotherapy and vaccines. JPT Peptide Technologies has substantial, long-standing expertise in providing peptides, peptidomimetics, and proteins to the global scientific community. Our highly skilled and committed scientific staff ensures that the most appropriate methods and techniques are selected for every synthesis project. All our catalog peptides are provided with HPLC-MS analyses to confirm the identity and demonstrate the high quality of our peptides.
Benefits of PepMix™
- Each peptide quality controlled and guaranteed for identity and purity
- CoA and HPLC-MS data available
- High batch-to-batch consistency
- No false positive T cell responses by contaminating deletion peptides
- No toxic inhibition of T cell responses due to stringent purification of each peptide
- Minimization of endotoxin contamination due to low bioburden process
- ADCF policy in place
- HLA independent stimulation (with antigen spanning peptide pools)
References:
Read References with Antigen Peptides
Properties | Values |
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Application: | Enzymology, Protein-protein-interaction, T-cell immunity |
Category: | Antigen Peptides |
Layout: | Freeze-dried in plastic vial |
Organism: | Artificial |
Protein Name: | Other, Selected proteins |
Purity: | Trial Grade: each peptide purified to > 90% (HPLC/MS) |
Quantification: | No |
Information | Values |
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Sequence: |
scrambled version of the antigen peptide selected by the customerThe scrambled peptide version has been cross-checked against the Uniprot database (https://www.uniprot.org/) to ensure that the sequence does not correspond to any natural sequence. Additionally, MHC binding predictions were utilized to screen against the most common HLA types (HLA-A01:01, HLA-A02:01, HLA-A03:01, HLA-A24:02, HLA-B*07:02). Only peptides that exceed an affinity threshold of 500 nM, which is routinely used for peptide selection (https://pmc.ncbi.nlm.nih.gov/articles/PMC3872965/), were chosen.
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