Humoral Immune Response

Our proprietary products and services for the study of humoral immunity range from high content PepStar™ Peptide Microarrays, PepSpot™ Arrays and RepliTope™ Multiwell Microarrays to Peptide ELISA and peptides conjugated to carriers and adjuvants. The reliability of these products allows not only the differential analysis of biological samples for immune profiling and epitope identification but also antibody generation and mimotope optimization at high efficiency.

PepStar™ Peptide Microarrays
PepStar™ peptide microarrays for profiling of cancer specific samples or antibodies, detection of epitopes or neo-epitopes, vaccine target identification, and monitoring epitope spreading. Peptide microarrays are reliable and efficient tools for screening assays such as the characterization of potential therapeutic antibodies, the identification of novel biomarkers, and the elucidation of protein/protein interactions.
Peptide microarrays can display overlapping peptide scans through antigens, or any other peptide sequences. You define content and layout and we provide economic and fast production of customized PepStar™ peptide micorarrays in our regulated clean-room environment. Or you choose one of our off-the-shelf peptide microarrays display overlapping peptide scans through antigenic 100s of proteins.

Peptide ELISA
We offer customized peptide-coated ELISA plates (enzyme-linked immunosorbent assay). ELISA is a well-established analytical and highly sensitive immunological assay for proteins but requires detailed experimental know-how for using peptides. Peptide ELISA is used for mapping of epitopes and definition of protein interaction sites or as validation assay to confirm results obtained with JPT’s peptide microarrays.

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PepSpots™ Peptide Arrays on Membrane
PepSpots™ are membrane-bound peptide arrays used for efficient and inexpensive antibody epitope mapping and protein-protein interaction studies. Peptides are synthesized by our proprietary SPOT technology directly on hydrophilic cellulose membranes, which minimize non-specific binding. Easy detection using standard ELISA protocols.
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Antibody Response Profiling
This modular assay service for antibody response profiling and biomarker discovery in patient samples analyzes humoral immune response in three steps. The three assay service modules can be combined or utilized individually according to your requirements.

  • High throughput antibody response profiling or biomarker screening, using thousands of custom peptides
  • Verification of the peptide hits for hundreds of samples
  • Validation of results by robust custom peptide ELISA

BioTides™ Biotinylated Peptides
BioTides™ Biotinylated Peptides are designed for biomedical screening assays that require immobilization onto streptavidin coated beads, membranes, glass slides or microtiter plates. They are the most inexpensive spurce of biotinylated peptides.
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Peptide Conjugates - KLH, BSA
Peptide conjugates with KLH, BSA or other proteins are used for effective immunization and generation of antibodies. We offer a peptide conjugation service based on our long-term experience.

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use of trichter humoral immunity
use of trichter humoral immunity
use of trichter humoral immunity

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