Cellular Immune Monitoring

Our peptide formats allow efficient profiling of target-specific cellular immune responses by cellular assays such as ELISPOT and Flow Cytometry. As successful immune monitoring has a huge impact on the success of clinical studies, JPT has developed unique peptide specifications that avoid peptide cross contamination, inhibit false positive T-cell stimulation by synthetic by-products, eliminate cell toxic by-products and allow for peptide stability monitoring, peptide solubility evaluation and more. For critical clinical trial monitoring JPT maintains a specification called ISO PLUS that complies with relevant regulatory requirements on line clearance, quality oversight, batch documentation and more. The combination of our long-term peptide chemistry and bioinformatics knowledge with highest regulated quality standards enables efficient, high quality clinical profiling of cellular immune responses.

PepMix™ Peptide Pools

Our antigen spanning PepMixes™ are available in a large variety of off-the-shelf peptide pools (e.g. for EBV, HCMV, Adenovirus, BKV, HHV6, and tumor associated antigens) or customized for your clinical application and antigens (e.g. epitope & neo-epitope, overlapping peptide pools and more). We also offer a wide variety of standardization and control pools such as CEFX Pools and HCMV (pp65).

Antigen Peptides

JPT offers specific epitope peptides for stimulation of T cells in interferon gamma-releasing T cell assays such as ELISPOT for efficient immune monitoring, mapping of T cell epitopes or development of immunotherapies and vaccines.

T Cell Assay Services

We offer T cell assays such as ELISpot, ICS/flow cytometry and multimer staining in our dedicated S2 lab, which operates according to strict ISO 9001 regulations. Additionally, we can assist you with target selection, sequence analysis/bioinformatics and peptide library design. Our service includes peptide synthesis, peptide pooling, matrix pool design & plating and the T cell assay.

Please visit T Cell Assay Services

Clinical Peptides & PepMix™ Peptide Pools

JPT’s Clinical Peptide product lines Clinical Grade and ISO Plus Peptides & PepMix™ Pools are produced in production environments regulated by an enhanced ISO 9001:2015 quality management system for the stringent product requirements of cell therapy such as adoptive cell therapy and dendritic cell pulsing. The resulting products have been shown to be applicable in various clinical applications.
use of clinical immune monitoring
use of clinical immune monitoring
use of clinical immune monitoring

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