RepliTope™ Peptide Microarrays
RepliTope™ peptide microarrays are off-the shelf peptide antigen microarrays, displaying overlapping peptide scans through antigenic proteins. RepliTope™ peptide microarrays are reliable and efficient tools for screening assays such as the characterization of potential therapeutic antibodies, the identification of novel biomarkers, and the elucidation of protein/protein and enzyme/substrate interactions. Additionally, we offer our comprehensive Peptide Microarray Assay and Incubation Service for outsourcing of experiments.
RepliTope™ Peptide Microarrays for Infectious Diseases
RepliTope™ Antigen Collection Catalog Peptide Microarrays
RepliTope™ Peptide Microarrays for Tumor Associated Antigens
RepliTope™ Catalog Peptide Microarrays for Infectious Diseases
Incubation Kit & Accessories
Applications for RepliTope™ Peptide Microarrays
- Screening of seromarkers for infectious and autoimmune diseases, allergies and cancer
- Development of phosphorylation dependent antibodies
- Epitope mapping using only minimal amounts of antibody
- Individual or parallel antibody profiling
- Profiling of neutralizing antibody action
- Immune Monitoring of humoral immune responses during clinical trials
"Antibody Signatures Defined by High-content Peptide Microarray Analysis"
by Schutkowski et al.
"The Other Microarrays: Detailed Mapping of Humoral Immune Response Using JPT Peptide Technologies' Peptide Microarrays and Tecan Array Technology"
by Pawlowski et al.
Benefits of RepliTope™ Peptide Microarrays
Testimonials for RepliTope™ Catalog Peptide Microarrays
"One focus of our group is to decipher the nature of immune responses by identification of biomarkers and indicators of immune protection. With the support of JPT's high content peptide microarray platform, we created a peptide chip which contains 22.000 individual peptides. This enabled the visualization of the B-cell "signature" in individuals with TB-infection vs. non- infected individuals. In our hands, JPT's peptide microarrays turned out to be very robust tools to identify novel peptide based biomarkers in the context of novel diagnostics and vaccine target identification."
Prof. Markus Maeurer, Karolinska Institute Sweden, Solna, Sweden
Selected References for RepliTope™ Peptide Microarrays
HIV-1 Envelope Proteins and V1/V2 Domain Scaffolds with Mannose-5 to Improve the Magnitude and Quality of Protective Antibody Responses to HIV-1
Morales et al., The journal of Biological Chemistry (2014) - PMID: 24872420 Investigation of Humoral Immune Response Towards Persisting Epstein-Barr Virus Infections in Multiple Sclerosis and Chronic Fatigue Syndrome Using Peptide Microarrays (TECH1P.868)
Scheibenbogen et al., J. Immunol. (2014) - PMID: n.a.
Multiple Sclerosis: The Elevated Antibody Response to Epstein-Barr Virus Primarily Targets, But is Not Confined to, The Glycine-alanine Repeat of Epstein-Barr Nuclear
Ruprecht et al., Journal of Neuroimmunology (2014) - PMID: n.a.
Whole CMV Proteome Pattern Recognition Analysis after HSCT Identifies Unique Epitope Targets Associated with the CMV Status
Pérez-Bercoff et al., PloSONE (2014) - PMID: 24740411
Generation and Characterization of Mouse Monoclonal Antibodies Against NS4B Protein of Dengue Virus
Xie et al., Virology (2014) - PMID: 24503088