RepliTope™ Peptide Microarrays
RepliTope™ peptide microarrays are off-the shelf peptide microarrays, displaying overlapping peptide scans through antigenic proteins. RepliTope™ peptide microarrays are reliable and efficient tools for screening assays such as the characterization of potential therapeutic antibodies, the identification of novel biomarkers, and the elucidation of protein/protein and enzyme/substrate interactions. Additionally, we offer our comprehensive Peptide Microarray Assay and Incubation Service for outsourcing of experiments.
Standard RepliTope™ Peptide Microarrays for Infectious Diseases (for 1 sample)
Multiwell RepliTope™ Peptide Microarrays for Infectious Diseases (for 21 samples)
RepliTope™ Antigen Collection Catalog Peptide Microarrays
Standard RepliTope™ Peptide Microarrays for Tumor Associated Antigens (for 1 sample)
Multiwell RepliTope™ Peptide Microarrays for Tumor Associated Antigens (for 21 samples)
Incubation Kit & Accessories
Applications for RepliTope™ Peptide Microarrays
- Screening of seromarkers for infectious and autoimmune diseases, allergies and cancer
- Development of phosphorylation dependent antibodies
- Epitope mapping using only minimal amounts of antibody
- Individual or parallel antibody profiling
- Profiling of neutralizing antibody action
- Immune Monitoring of humoral immune responses during clinical trials
"The Challenge of Antigen Sequence Diversity: Solutions with ULTRA‐Peptide Libraries"
by Pawlowski et al.
"Multiple Sclerosis and Epstein‐Barr Virus Infection. An Epitope Mapping Study"
by Reimer et al.
"Antibody Signatures Defined by High-content Peptide Microarray Analysis"
by Schutkowski et al.
"The Other Microarrays: Detailed Mapping of Humoral Immune Response Using JPT Peptide Technologies' Peptide Microarrays and Tecan Array Technology"
by Pawlowski et al.
Benefits of RepliTope™ Peptide Microarrays
Testimonials for RepliTope™ Catalog Peptide Microarrays
"One focus of our group is to decipher the nature of immune responses by identification of biomarkers and indicators of immune protection. With the support of JPT's high content peptide microarray platform, we created a peptide chip which contains 22.000 individual peptides. This enabled the visualization of the B-cell "signature" in individuals with TB-infection vs. non- infected individuals. In our hands, JPT's peptide microarrays turned out to be very robust tools to identify novel peptide based biomarkers in the context of novel diagnostics and vaccine target identification."
Prof. Markus Maeurer, Karolinska Institute Sweden, Solna, Sweden
Selected References for RepliTope™ Peptide Microarrays
"Superior Efficacy of an HIV Vaccine Combined with ARV Prevention in SHIV Challenged Non-human Primates"
Le Grand et al., Journal of Virology (2016) - PMID: 27009957
"Protective Efficacy of Adenovirus-protein Vaccines Against SIV Challenges in Rhesus Monkeys"
Barouch et al., Science (2015) - PMID: 26138104
"Structure of GPN-loop GTPase Npa3 and Implications for RNA Polymerase II Assembly"
Niesser t al., Mol Cell Biol. (2015) - PMID: 26711263
"Identification and Characterization of Common B Cell Epitope in Bovine Leukemia Virus via High-throughput Peptide Screening System in Infected Cattle"
Bai et al., Retrovirology (2015) - 26715158
"Peptide Microarrays for Coverage of Sequence Diversity in Monitoring the B cell Immune Response (TECH2P.911)"
Castro, et al., The Journal of Immunology (2015) - PMID: n.a.
"H1N1 Viral Proteome Peptide Microarray Predicts Individuals at Risk for H1N1 Infection and Segregates Infection Versus Pandemrix® -Vaccination"
Aditya et al., Immunology (2015) - PMID: 25639813
"HIV-1 Envelope Proteins and V1/V2 Domain Scaffolds with Mannose-5 to Improve the Magnitude and Quality of Protective Antibody Responses to HIV-1"
Morales et al., The journal of Biological Chemistry (2014) - PMID: 24872420
"Whole CMV Proteome Pattern Recognition Analysis after HSCT Identifies Unique Epitope Targets Associated with the CMV Status"
Pérez-Bercoff et al., PloSONE (2014) - PMID: 24740411
"Generation and Characterization of Mouse Monoclonal Antibodies Against NS4B Protein of Dengue Virus"
Xie et al., Virology (2014) - PMID: 24503088
Read More References with RepliTope™ Peptide Microarrays
Profile Circulating Antibodies Against 1882 Cancer Peptides with our new RepliTope™ Antigen Collection TAA displaying TAS such as Erb/Her2, Mage, NY-ESO-1, PSA and Survivin.
Analyze 21 Samples on a Single Microarray with our new RepliTope™ Multiwell Microarrays available for Tumor Antigens and Infections