PepTrack™ Peptide Libraries

JPT's customized peptide libraries are optimized for:
  •  Antigen-specific stimulation in T-cell assays
  •  Immune monitoring
  •  T-cell epitope identification
  •  T-cell epitope mapping
  •  Development of cellular therapy and immunotherapy approaches
  •  Vaccine development
We offer our tailored peptide libraries of immunogenic or antigenic peptides with flexible specifications (peptide purity, amount of QC). To help you avoid false positives or toxic inhibition of T-cells, we defined specific parameters for synthesis, purification and analysis. 

Please contact our customer support team to discuss peptide library specifications that are best suited to your application!
All peptide synthesis is performed in our laboratories in Berlin, Germany under strict regulations according to our ISO 9001:2015 certification.

Select your PepTrack™ Peptide Library

 PEPTRACK™
OPTION                
APPLICATIONS PURITY QC SCALE
Fast Track T-cell epitope discovery, Antigen target identification, Pathogen-spanning T-cell epitope discovery Unpurified Statistical LC-MS (5% of all peptides) 10-50µg of target peptide
Fast Track PLUS Neo-epitope prioritization, Target identification, Biological screening Unpurified LC-MS and quantitation of each peptide 10-50µg of target peptide
Research Track T-cell epitope discovery, Immunogenicity testing, Identification of immunodominant antigens Unpurified (each peptide detectable by LC-MS or MALDI-MS) LC-MS / Maldi-MS for each peptide 1-5mg
Research Track PLUS T-cell epitope discovery, Target identification, Biological screening with each peptide analyzed by LC-MS Unpurified (Major product component is guaranteed to be peptide of interest) LC-MS for each peptide 1-5mg
Development Track Immune monitoring, T-cell epitope mapping >70% LC-MS for each peptide 1-5mg
Trial Track Clinical immune monitoring, Development of immunotherapy

>80%
>90%
>95%
>97%

LC-MS for each peptide 1-5mg
Fast Track Peptide Libraries
  • Applications: T-cell epitope discovery, target identification, biological screening
  • Purity: Unpurified
  • QC /QA: Statistical LC-MS of 5% of the peptides
  • Peptide Length: 6-15 aa (for longer peptides, please inquire)
  • Amount per Peptide: 10-50µg of target peptide (larger amount upon request)
  • Delivery Format: Freeze-dried in 96 well plates
  • Delivery Time: 2 weeks minimum
  • Minimum Order: 24 peptides
Fast Track PLUS Peptide Libraries
  • Applications: T-cell epitope discovery, target identification, biological screening
  • Purity: Unpurified
  • QC /QA PLUS: LC-MS and quantitation of each peptide included
  • Peptide Length: 6-15 aa (for longer peptides, please inquire)
  • Amount per Peptide: 10-50µg of target peptide (larger amount upon request)
  • Delivery Format: Freeze-dried in 96 well plates
  • Delivery Time: 3 weeks minimum
  • Minimum Order: 24 peptides
Research Track Peptide Libraries
  • Applications: T-cell epitope discovery, target identification, biological screening with each peptide analyzed by LC-MS
  • Purity: Unpurified (each peptide must be detectable by LC-MS or MALDI-MS)
  • Capping: Truncated peptides are capped after each synthesis step. This eliminates the major source of false positive T-cell responses, deletion peptides.
  • QC /QA: LC-MS / Maldi-MS for each peptide
  • Peptide Length: 15 aa
  • Amount per Peptide: 1-5 mg (larger amounts available)
  • Delivery Format: Freeze-dried in 96 tube racks
  • Delivery Time: 2-4 weeks
  • Minimum Order: 24 peptides
Research Track PLUS Peptide Libraries
  • Applications: T-cell epitope discovery, target identification, biological screening with each peptide analyzed by LC-MS
  • Purity PLUS: Major product component according to LC-MS analysis is guaranteed to be peptide of interest
  • Capping: Truncated peptides are capped after each synthesis step. This eliminates the major source of false positive T-cell responses, deletion peptides.
  • QC /QA: LC-MS for each peptide
  • Peptide Length: 15 aa
  • Amount per Peptide: 1-5 mg (larger amounts available)
  • Delivery Format: Freeze-dried in 96 tube racks
  • Delivery Time: 2-4 weeks (depending on number of peptides)
  • Minimum Order: 24 peptides
Development Track Peptide Libraries
  • Applications: Antigen-specific stimulation of T-cells for immune monitoring and other applications that require defined peptide purity
  • Purity: > 70% guaranteed for each peptide
  • Capping: Truncated peptides are capped after each synthesis step. This eliminates the major source of false positive T-cell responses, deletion peptides.
  • QC /QA: LC-MS for each peptide
  • Peptide Length: 15 aa
  • Amount per Peptide: 1-5 mg (larger amounts upon request)
  • Delivery Format: Freeze-dried in 96 tube racks
  • Delivery Time: 4-5 weeks
  • Minimum Order: 24 peptides
Trial Track Peptide Libraries
  • Applications: Antigen-specific stimulation of T-cells for immune monitoring or immunotherapy in clinical trials
  • Quality: For even higher quality, please check our Clinical Peptides & Pools!
  • Purity: > 80%, 90%, 95% or 97% guaranteed for each peptide
  • Capping: Truncated peptides are capped after each synthesis step. This eliminates the major source of false positive T-cell responses, deletion peptides.
  • QC /QA: LC-MS for each peptide
  • Peptide Length: 15 aa
  • Amount per Peptide: 1-5 mg (larger amounts upon request)
  • Delivery Format: Freeze-dried in 96 tube racks
  • Delivery Time: 4-5 weeks
  • Minimum Order: 24 peptides
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Applications

Applications for PepTrack™ Peptide Libraries

  • Immune monitoring profiling by ELISpot
  • T-cell epitope discovery, mapping & validation
  • Peptide vaccine & development
  • Optimization and validation of T-cell assays
  • Translation of NGS results into neo epitope libraries
  • Vaccine efficacy testing
  • Immunotherapy
  • Biological screening

Application Notes

A Fast & Low Cost Process for Neo-Epitope Based Immune Monitoring
Derhovanessian et al. (2017) Full Text 
Strategy for Identification of CD8 T‐cell Epitopes in a Viral Protein
Holtappels (2015) Full Text
Qualification and Use of Peptide Libraries for Clinical Trial Immunomonitoring
Cox & Hayes (2013) Full Text
Characterization of the Aspergillus Specific T-cell Response by Using Crf1 and Catalase 1 Overlapping Peptides
Jolink & Heemskerk (2014) Full Text
Benefits

Benefits of PepTrack™ Peptide Libraries

  • Flexible peptide libraries tailored for cellular assays
  • Best pricing in industry!
  • DIN EN ISO 9001:2015 & GCLP standards; audits welcome!
  • Custom Peptide Synthesis avoiding toxic inhibition or de novo epitopes
  • Aliquotation, pooling and advanced QC (UPLC, AAA, residual solvent determination, stability testing, etc.)
  • Post-Translational Modifications (PTMs) available
  • Proven track record for applications in clinical studies
Testimonials

Testimonials for PepTrack™ Peptide Libraries

 “My group at the Virology Department of the UK Animal Health and Veterinary Laboratories Agency focuses on defining the T cell target antigens of important veterinary viral pathogens and the exploitation of this information in the development of new/improved vaccines. Our need for economic whole viral proteome spanning peptide libraries led us to JPT's PepTrack™ Peptide Libraries. The sensitivity of our cellular assays towards cytotoxic contaminants as well as impurities yielding in unwanted T-cell stimulation prompted a systematic evaluation of peptide sources. JPT turned out to be the most reliable vendor regarding both delivery time and high quality levels based on a certified Quality Management System. I am collaborating with JPT for many years and certainly recommend their services.”
Simon Graham, PhD (Virology Department of the UK Animal Health and Veterinary Laboratories Agency, Addlestone, Surrey, UK

"I have been collaborating with JPT for several years. Their unique peptide library technologies and knowledge of specific peptide requirements for T-cell assays made them a valuable, long-term partner in our efforts to develop novel adoptive immunotherapy approaches to prevent and treat viral infections post-transplant as well as for the treatment of virus and non virus-associated malignancies. Furthermore, their reagents allow us to precisely monitor and track specific T cell populations post-infusion"
Ann Leen, PhD (Baylor College of Medicine, Center for Cell and Gene Therapy, Houston, TX, USA)

“We utilize JPT’s peptide libraries and pools for T-cell epitope mapping and immune monitoring applications such as ELISPOT and ICS, as well as CFC. The combination of synthesis economy, quick turnaround time and tailored specifications are key to our success. JPT’s scientific competence is invaluable for all institutions planning to employ peptides in immuno assays for research or clinical setups."
Johannes Hampl, PhD (Anza Therapeutics, Inc Concord, CA, USA)

References

References for PepTrack™ Peptide Libraries

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Health - made in Germany
Quality Assurance

All production is ISO 9001:2015 certified.

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