JPT's unique PepStar™ peptide microarrays are high-content or multiwell peptide arrays on glass slides. Peptide microarrays (or peptide chips) are used for biomarker discovery, immunomonitoring, antibody epitope mapping, multiplexed epitope mapping or for detection and validation of protein interactions. In addition, PepStar™ peptide microarray technology also enables enzyme profiling.
Chemical peptide synthesis is followed by peptide immobilization on glass slides via a flexible linker. Using chemoselective coupling, we generate peptide microarrays displaying directed and covalently attached peptides. Multiple identical copies of each peptide microarray can be prepared with flexible layouts at unmatched prices and turnaround times.
Have a look at our incubation and assay services for epitope mapping and discovery!
Antibody Epitope Discovery Service and Antibody Response Profiling.
- Mapping of immunodominant regions in antigens
- Antibody epitope mapping and optimization
- Elucidation of signal transduction pathways
- Identification of substrates for orphan enzymes
- Optimization of known enzyme substrates
- Reliable detection of contaminating enzyme activities
The Challenge of Antigen Sequence Diversity: Solutions with ULTRA‐Peptide Libraries
by Pawlowski et al.
Multiple Sclerosis and Epstein‐Barr Virus Infection. An Epitope Mapping Study
by Reimer et al.
Rapid Mimotope Optimization for Pharmacokinetic Analysis of the Novel Therapeutic antibody IMAB362
by Daneschar et al.
Antibody Signatures Defined by High-Content Peptide Microarray Analyses
by Schutkowski et al.
A Modular Approach for Epitope Discovery and High-Resolution Profiling of Humoral Immune Responses
by Pawlowski et al.
- Get hundreds of identical microarray copies from one peptide synthesis
- Peptides are free of truncated sequences
- Small amounts of your precious samples are needed for incubation
- Low background on glass surface & read-out via fluorescence
- Obtain Peptide ELISAs and individual custom peptides for validation
- Flexible peptide microarray layout, e.g. for automated incubation and multiwell microarray incubation
- Check out our assay services!
Antibody Epitope Discovery Service and Three-Step Seromarker Discovery Service.
"The RV 144 HIV trial is considered as one of first successful HIV vaccinetrials. It has become clear that the V2 loop of gp120 is an important site for immunogenicity and protection from HIV infection. The use of JPT's PepStar™ microarray technology has been very useful for the correlation of the clincial outcome with humoral immune responses. As have the cyclicpeptides been from JPT to validate these findings!"
Jeff Currier, PhD, Walter Reed Army Institute, Rockville, Maryland, USA
"Over the past five years my research team has been active in the development of species-specific peptide arrays. Our ability to advance this technology into new research areas has been dependent on working with the highest quality of arrays. In this regard, JPT’s commitment to excellence has been a critical foundation for the success of our research program. I have been consistently impressed with their customer service, technical expertise and professionalism. When it comes to peptide synthesis there are no other options for our group…JPT is the best."
Scott Napper, PhD, Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Canada
Three-Step Seromarker Profiling Service
Comprehensive and modular seromarker discovery workflow ranging from high throughput screening and parallel verification of peptide hits for hundreds of samples to validation of results by robust peptide ELISA
Epitope Discovery Service
Mapping of binding sites and antibody signature profiling using our PepStar™ peptide microarrays
RepliTope™ Catalog Microarrays
Peptide chips for mapping immunodominant regions in antigens
Kinase Peptide Microarrays
Compilation of kinase substrate peptides on ready-to-use PepStar peptide microarrays
Immune Checkpoint Inhibitors We launch new PepMixes™ and RepliTopes™
representing immune checkpoint inhibitors hPD-1, PD-L1, PD-L2 and CTLA4!
Address Sequence Diversity
with NEW ULTRA Peptide Microarrays for HIV and Malaria
Analyze 21 Samples on a Single Microarray with our new RepliTope™ Multiwell Microarrays available for Tumor Antigens and Infections