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Histone Code Peptides, Microarrays & ELISA

As histones are a major focus of epigenetics, JPT’s Bioinformaticians have compiled a unique library of thousands of post-translationally modified and unmodified histone peptides. We offer this peptide library immobilized on Histone Code Peptide Microarrays or Histone Code Peptide ELISA, as purified individual Histone Code Peptides and as stable isotope labeled and quantified SpikeTides™ Set. 

Properties of the Histone Peptide Library:

  • Peptides from Histone H1, Histone H2A, Histone H2B, Histone H3 and Histone H4
  • Post-translational modifications in various combinations representing many potential variants
  • Post-translational modifications: Lys[acetylation, (mono-, di-, tri-) methylation, butyrylation, propylation, succinylation, malonylation]; Arg[mono-methylation, di-methylation (symmetric and asymmetric], Citrullin, and Ser, Thr, Tyr [phosphorylation]
  • Use our custom peptide synthesis for any histone peptide we do not have in stock.

Individual Histone Peptides

Individual Histone Peptides

We offer a huge selection of histone peptides from Histones H2A, H2B, H3 and H4 with many post-translational modifcations and optional biotinylation, from histone tails and core sequences.  Select your histone, modification(s) and histone isoform and receive your histone peptide within days!

All our histone peptides are produced as high quality peptides, purified and qualified by HPLC-MS and arrive as freeze-dried aliquots for increased shelf stability.

For further information, pricing and the full peptide list please visit our online shop

Applications for Histone Code Peptides & Microarrays

  • Mapping and validation of protein-histone interactions including PTM dependencies
  • Testing of histone antibodies including PTM dependencies
  • Enzymatic activity profiling including PTMs

Application Note:
"Histone PTM Profiling Reveals Global and Specific Responses to Systematic Enzyme Ablations"
by Feller et al.
"Comprehensive Characterization of Antibodies Directed towards Epigenetic Histone-Modifications"
by Masch et al.
"Use of High-Density Histone Peptide Arrays for Parsing the Specificity of a Histone-Modifying Enzyme Complex"
by Shechter et al.

Benefits of Histone Code Peptides, ELISA & Microarrays

  • Coverage of all known natural variants (sequence variants and PTMs)
  • Identical sequences on peptide microarray, peptide ELISA and as individual peptides for reliable and checkable results
  • All-in-one Histone Code Analysis Service for antibody specificity & histone reader profiling
  • Guaranteed purity for each individual peptide and peptide ELISA
  • Ready-to-use lyophilized aliquots for individual peptides

Testimonial for Histone Code Peptides, Microarrays & ELISA

" JPT’s new extremely high-density histone peptide array is a dramatic leap forward for analysis of the histone code hypothesis. The complete sequence coverage across core histones and histone variants as well as the presence of common and rare histone post-translational modifications – alone and in combination – makes this an unparalleled tool for studying the “writers” and “readers” of the histone code. My laboratory has used these arrays to ask the sequence and PTM dependence of a histone writer enzyme and we have discovered an activity specifying code that will keep us busy for years to come."
David Shechter, PhD, Department of Biochemistry, Albert Einstein College of Medicine,  Yeshiva University, NY, USA

News Highlights

20% Discount on Histone Products!
Have a look at our new Histone Code Tools & Services and latest Application Notes!
(July 2015)
Efficient & Economic: Histone Code Peptide ELISA
Screen 94 post-translationally modified histone sequences from 
Histone H2A, Histone H2B,  Histone H3 & Histone H4!
(March 2013)
--> Read more news

Quality Assurance

All production is performed according to ISO 9001:2015 standards

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