Our proprietary peptide-based humoral immune monitoring technologies allow high resolution profiling of antibody related immune responses. Purified antibodies, patient sera and even whole blood can be used with our assay platforms targeting specific antigens, entire antigen families or selected epitopes and neo-epitopes. This allows effective B-cell epitope resolved elucidation of antibody responses in clinical studies as well as recognition of certain epitope patterns and epitope spreading. Additionally, we can address natural sequence diversity, mutations and post-translational modifications that occur in cancer cells and different types of viruses.
Our customized peptide microarrays offer profiling of cancer specific samples or antibodies, detection of epitopes and epitope spreading and vaccine target identification. Our peptide microarrays display overlapping peptide scans through antigens, or selected amino acid sequences. You define the content and layout; we the economic and fast production in our regulated clean-room environment. We also offer our assay and analysis service using your samples with custom tailored peptide microarray.
> PepStar™ Peptide Microarrays
We offer customized peptide-coated ELISA plates (enzyme-linked immunosorbent assay). ELISA is a well-established analytical and highly sensitive immunological assay for proteins but requires detailed experimental know-how for using peptides. Peptide ELISA is used for mapping of epitopes and definition of protein interaction sites or as validation assay to confirm results obtained with JPT’s peptide microarrays.
> Peptide ELISA
PepSpots™ are membrane-bound peptide arrays used for efficient and inexpensive antibody epitope mapping and protein-protein interaction studies. Peptides are synthesized by our proprietary SPOT technology directly on hydrophilic cellulose membranes, which minimize non-specific binding. Easy detection using standard ELISA protocols.
> PepSpots™ Peptides on Cellulose