Peptide Modifications

JPT's Peptide Modification Services

Did you know that JPT is a recognized quality leader in custom peptide synthesis services? As peptide experts, we bring decades of experience, extensive production capabilities, and a strong reputation for excellence in peptide modification services and quality control. We are your one-stop shop for all things peptide.

Our robust quality management system ensures not only the highest standards of quality but also guarantees the reproducibility and reliability of your peptides. With an impressive success rate of over 99% in synthesizing target peptides—a true testament to our commitment and expertise—we offer a wide range of modifications and specifications tailored to your needs.


Why Modify Peptides? 

Peptide modifications can dramatically alter the function, stability, and applicability of a synthetic peptide. Our modification services are designed to help you:

  1. Improve Peptide Stability: cyclic peptides, D-amino acid substitution , and disulfide bonds enhance proteolytic resistance and extend peptide half-life.
  2. Enhance Binding Affinity & Specificity:  Site-specific changes and labeled side chains increase interaction with carrier proteins, enzymes, or antibodies.
  3. Boost Bioactivity: Conjugations such as biotinylation or attachment to carrier molecules enhance performance in assays or therapeutic models.
  4. Increasing or Reducing Immunogenicity: Through glycosylation, methyl amino acids, or unnatural residues, you can fine-tune immune responses or mimic naturally occurring peptides and proteins.
  5. Enable Imaging & Mass Spectrometry: in diagnostics, fluorescently or isotope labeled peptides can be used as reference markers.
  6. And Many More...

Our Expertise in Functional Peptide Modifications

Our portfolio includes an extensive variety of peptide Specialties & Modifications to meet diverse research and development needs. Our specialties include:  

  • Biotinylated and Tagged Peptides 
  • Click Chemistry 
  • Cyclic Peptides 
  • Cysteine Modifications 
  • C-Terminal Modifications 
  • Fluorescent Dye Labeled Peptides 
  • Internally Quenched / FRET Peptides 
  • Isotope Labeled Peptides 
  • Linker / Spacer / PEGylations 
  • Long Peptides 
  • Lysine & Arginine Modifications
  • Macrocyclic Peptide Synthesis 
  • N-Terminal Modifications 
  • Peptide Dimers 
  • Peptidomimetics 
  • Unnatural Amino Acids 


Our Post-Translational Modifications include: 

  • Glycopeptides (Glycosylated Peptides) 
  • Methionine Modifications 
  • Methylated Peptides 
  • Phosphopeptides (Phosphorylated Peptides) 
  • Sulfated Peptides 


If you have not found your type of PTMs and specifications in this list, do not hesitate to reach out and investigate further post-translational modifications. 

Contact us!


Our Modification & Specifications Services:


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