Alanine Scanning Library
What Is an Alanine Scanning Library?
An Alanine Scanning Library is a powerful research tool used to study the function of individual amino acids within a peptide or protein. This method involves systematically replacing each amino acid, one at a time, with alanine, a small, non-polar residue. Alanine substitution helps determine which residues are essential for biological activity, molecular binding, or protein structure. Since alanine does not significantly disrupt the protein backbone, it provides a clear view of the importance of side-chain interactions.
Applications of Alanine Scanning Libraries
Alanine scanning is widely used across various research and development fields to uncover functional details in peptides and proteins. By identifying which amino acids are essential for activity or interaction, these libraries support a range of scientific goals, including:
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Epitope mapping; Identify key residues involved in antibody or T cell recognition.
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Receptor-ligand analysis; Determine which parts of a peptide or protein are critical for binding.
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Protein engineering; Guide the design of more stable or functional protein variants.
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Drug discovery and development; Pinpoint molecular targets and optimize lead compounds.
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Enzyme mechanism studies; Reveal which residues contribute to catalytic activity.
These applications make alanine scanning a powerful strategy for improving molecular understanding and advancing biomedical research.
JPT’s Specialization in Alanine Scanning Libraries
JPT offers custom-designed Alanine Scanning Libraries with exceptional precision and quality, supporting detailed structure-function analysis of peptides and proteins. With extensive experience in peptide synthesis and high-throughput screening, JPT delivers libraries tailored to your sequence and research goals—whether for epitope mapping, binding studies, or drug development. Our solutions are trusted by researchers worldwide for their reliability, reproducibility, and scientific impact.
Available Alanine Scanning Library Formats
Custom Peptide Libraries
Amount: from 1 mg per peptide
Purity: Crude to 95%
Delivery Format: 96 MTP or Individual Tubes
Customized Modifications
Peptide Microarrays
Peptides printed on array
Low to high density
Flexible microarray layout
Ideal for identifying key residues
Custom Peptide Synthesis
Amount:
from 1 mg up to gram scale
Purity: Crude to >95%
Format: Customizable upon request
Tailored to your specific research needs
Why Researchers Trust JPT
Researchers worldwide rely on JPT for alanine scanning due to our commitment to quality, precision, and customer support. Our advanced synthesis techniques ensure highly pure and accurate peptide variants, while customized designs meet specific research needs. Key reasons for choosing JPT include:
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High-quality, reproducible peptide libraries
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Tailored solutions for diverse research applications
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Fast turnaround times and reliable delivery
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Expert technical support throughout the project
These strengths make JPT a trusted partner in peptide research and discovery.