Understanding DOTA Peptides and Their Applications
DOTA (tetraxetan) is a versatile chelating agent with a high affinity for di- and trivalent cations like 177Lu, 68Ga, and 64Cu. These radionuclides are critical in medical applications, particularly in cancer diagnosis and treatment. The DOTA peptide structure enables it to securely bind these cations, making it an ideal candidate for use in advanced therapies such as Peptide Receptor Radionuclide Therapy (PRRT). PRRT leverages DOTA peptides to deliver targeted radiation to neuroendocrine tumors, providing a potent treatment option for unresectable cancers.
JPT's Expertise in DOTA Peptide Synthesis
Off-the-Shelf DOTA Peptides
At JPT Peptide Technologies, we offer a range of high-affinity DOTA peptides specifically designed for somatostatin receptors, which are commonly found on neuroendocrine tumors. Our DOTA peptide offerings include:
- DOTATOC (DOTA-(Tyr3)-octreotide or edotreotide): A widely used peptide in PRRT for its strong receptor affinity.
- DOTA-TATE (DOTA-(Tyr3)-octreotate): Known for its effectiveness in targeting neuroendocrine tumors.
- DOTA-NOC (DOTA-[Nal3]-octreotide): Provides an alternative with high receptor specificity.
These DOTA peptides are available off-the-shelf, ensuring rapid availability for your research or clinical applications.
You can send us a quote request to discuss your own custom DOTA peptides
or find the peptides you need here:
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![DOTA-NOC (DOTA-[Nal3]-octreotide)](https://media.jpt.com/Media/Images/Icons/icon_custom_peptides.svg "DOTA-NOC (DOTA-[Nal3]-octreotide)"){kind=icon}
Why Choose JPT for Your DOTA Peptide Needs?
Expertise and Innovation
With over 20 years of experience, JPT Peptide Technologies is a leader in the peptide synthesis field. We are pioneers in patented technologies for peptide libraries, pools, and microarrays, and our state-of-the-art laboratories in Berlin, Germany, are ISO 9001:2015 certified. Our extensive expertise ensures that every peptide we produce meets the highest standards of quality and performance.
Comprehensive Support for Your Projects
From initial project evaluation to final peptide delivery, our team of experts is here to support you. Whether you need a single DOTA peptide for a specific application or a large-scale production for clinical use, we are committed to providing you with the highest quality peptides tailored to your exact needs.
Contact Us Today
For more information on our DOTA peptide offerings or to discuss a custom synthesis project, please contact us or request a quote. Let us help you achieve your research and clinical goals with our superior peptide solutions.