The PepMix™ Human MOG (1-125) peptide pool combines 29 overlapping peptides from a 125-amino-acid region of human myelin oligodendrocyte glycoprotein, corresponding to UniProt Q16653 residues 30-154. Its peptide scan uses 15mers with an 11-amino-acid overlap and is supplied as a pooled reagent for cellular immune assays. This MOG control peptide pool can serve as a negative antigen control when its suitability has been established for the donor samples and assay, because MOG-reactive T cells may produce a response.
PepMix™ Human MOG (1-125) Peptide Pool - Specifications
- Amount: 25 µg (approx. 15 nmol) / peptide (for stimulation of up to 2,5 x 108 cells)
- Purity: Development Grade: each peptide purified to > 70% (HPLC/MS) - (equivalent to an average purity of 85%)
- Delivery Format: Freeze-dried in glass vial
- Application(s): T-cell Immunity
- Condition(s)/Topic(s): Control
- Standard Delivery Time: 2-5 days
Applications
- Negative antigen-control conditions in ELISpot and intracellular cytokine staining (ICS), following assay-specific qualification.
- Assessment of cellular reactivity to the covered human MOG region in antigen-specific T-cell assays.
- Comparison of MOG-stimulated and control conditions in cytokine or proliferation studies.
Human MOG Control Pool for Cellular Immune Assays
PM-MOG belongs to JPT’s Control Pools and provides a defined human self-antigen preparation for T-cell assay workflows. The MOG 1-125 peptide pool covers the specified 125-aa region, rather than the entire precursor sequence. For product selection across formats, visit the MOG peptides overview.
29 Overlapping Peptides in One Pooled Reagent
The pooled format removes the need to combine 29 individual peptide stocks before testing the covered antigen region. Each peptide is purified to >70% by HPLC/MS, and the vial contains 25 µg of each peptide. Stating coverage and per-peptide amount explicitly helps researchers compare antigen inputs and plan control conditions.
Need a different sequence or peptide preparation?
Discuss your project-specific peptide requirements through Custom Peptide Synthesis.
-Peptide-Pool.jpg "PepMix™ Human MOG (1-125) Peptide Pool")
-Peptide-Pool.jpg "PepMix™ Human (Actin)")
.jpg "Antigen Peptide MOG - HLA-DRB1*15:01 (MEVGWYRPPFSRVVHLYRNGK)")
.jpg "MOG (35-55), Mouse Peptide (MEVGWYRSPFSRVVHLYRNGK)")
