The Hexon protein is the largest and most abundant protein found in human adenoviruses (HAdVs), playing a crucial role in the virus's structure and immune response evasion. Its significance in the fields of gene therapy, cancer research, and infectious diseases has made it a focal point for peptide synthesis, particularly in applications involving T-cell immunity. Understanding and targeting the Hexon protein is essential for developing advanced therapeutic approaches and vaccines.
Pool of 236 peptides derived from a peptide scan (15mers with 11 aa overlap) through Hexon Protein (Swiss-Prot ID: B2ZWZ4) of Human Adenovirus (HAdV) - type 26.
PepMix™ Human Adenovirus 26 (Hexon Protein) - Specifications
Amount: 25 µg (approx. 15 nmol) / peptide (for stimulation of up to 2,5 x 10
8 cells)
Purity: Research Plus Grade: each peptide is guaranteed to be main product (HPLC/MS)
(equivalent to an average purity of 70%)
Delivery Format: Freeze-dried in glass vial
Application(s): T-cell Immunity
Condition(s)/Topic(s): Gene therapy, Cancer, Infection
Standard Delivery Time: 2-5 days
Advantages of Using PepMix™ Human Adenovirus 26 (Hexon Protein)
By choosing our PepMix™ Human Adenovirus 26 (Hexon Protein), researchers gain access to:
- High-Throughput Capability: Our facilities can handle the synthesis of tens of thousands of peptides monthly, ensuring rapid project turnaround.
- Customization Options: We offer tailored peptide formats, purity levels (up to >98%), and optional modifications such as phosphorylation, biotinylation, dye labeling, cyclization, conjugation, and stable-isotope labeling.
- Consistency and Quality: With over 20 years of experience, our peptides are manufactured with the highest standards of consistency and quality.
Applications of Hexon Protein in Gene Therapy and Immunotherapy
The Hexon protein plays a pivotal role in the development of adenovirus-based gene therapy vectors. It is a critical component for the design of vaccines and immunotherapies, particularly those aimed at stimulating a robust T-cell response. Our PepMix™ pool provides researchers with the tools necessary to explore these avenues, enabling groundbreaking advancements in the treatment of cancer, genetic disorders, and viral infections.
Custom PepMix™ Peptide Pools Tailored to Your Research Needs
Are you looking for a custom solution? We offer fully customizable PepMix™ peptide pools tailored to your specific research needs. Select your desired sequence, amount, purity, and pool format. Our team of experts will guide you through the process to ensure optimal results.
Fast and Reliable Delivery
We understand the urgency of research timelines. That's why our PepMix™ Human Adenovirus 26 (Hexon Protein) is available for standard delivery within 2-5 days. Whether you're working on gene therapy vectors or exploring new cancer treatments, our prompt delivery ensures your research progresses without delay.
Contact Us for More Information
For more information about our PepMix™ Human Adenovirus 26 (Hexon Protein) or to discuss your custom peptide needs, visit our webpage on Gene Therapy Vectors & Tools. Our team is ready to assist you in achieving your research goals.
Are you interested in your own custom PepMix? Choose your sequence, amount, purity and pool format. We will assist you along the way. Custom PepMix Peptide Pools.
More about our PepMix™ Peptide Pools:
PepMix™ Peptide Pools
Protein-spanning mixtures of overlapping peptides (PepMix™) are extremely efficient for
- Antigen-specific T cell stimulation in T cell assays (e.g. in ELISpot, ICS, cell-mediated cytotoxicity or proliferation assays)
- In-vitro T cell expansion
- Dendritic cell pulsing
- Immune monitoring
- Cellular immune response profiling
- T cell epitope identification
- Standardization of T cell assays
Benefits of PepMix™
- Each peptide quality controlled and guaranteed for identity and purity
- CoA and HPLC-MS data available
- High batch-to-batch consistency
- No false positive T cell responses by contaminating deletion peptides
- No toxic inhibition of T cell responses due to stringent purification of each peptide
- Minimization of endotoxin contamination due to low bioburden process
- ADCF policy in place
- HLA independent stimulation (with antigen spanning peptide pools)
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