PM-C-BKV-1

PepMix™ Collection BKV (2x1ug/peptide)

US$543.00

Currently out of stock, available again soon

Description

About PepMix™ Collection BKV (2x1ug/peptide)

AGP, LTA, STA, VP1, VP2, VP3, VP4

PepMix™ Collection BKV (2x1ug/peptide) - Specifications

Amount: 2 x aliquots of each peptide pool (1µg /peptide /pool)
Purity: Development Grade: each peptide purified to > 70% (HPLC/MS)
(equivalent to an average purity of 85%)
Delivery Format: Freeze-dried in 1 x 96 tube rack
Application(s): T-cell immunity
Condition(s)/Topic(s): Merkel cell carcinoma, Nephritis, interstitial, Infection, Opportunistic infections
Standard Delivery Time: approx. 10 days

PepMix™ Peptide Pools
Protein-spanning mixtures of overlapping peptides (PepMix™) are extremely efficient for
- Antigen-specific T cell stimulation in T cell assays (e.g. in ELISpot, ICS, cell-mediated cytotoxicity or proliferation assays)
- In-vitro T cell expansion
- Dendritic cell pulsing
- Immune monitoring
- Cellular immune response profiling
- T cell epitope identification
- Standardization of T cell assays

Benefits of PepMix™
- Each peptide quality controlled and guaranteed for identity and purity
- CoA and HPLC-MS data available
- High batch-to-batch consistency
- No false positive T cell responses by contaminating deletion peptides
- No toxic inhibition of T cell responses due to stringent purification of each peptide
- Minimization of endotoxin contamination due to low bioburden process
- ADCF policy in place
- HLA independent stimulation (with antigen spanning peptide pools)

References

References for PepMix™ Collection BKV (2x1ug/peptide)

References
Read References with
PepMix™ Peptide Pools for Infectious Diseases
PepMix™ Control Pools

Application Notes
Cross-reactive T cells enhance immune responses in SARS-CoV-2 infection and vaccination
Loyal et al (2021) Full text
Peptide Tools to Support the Fight against COVID-19
Alem et al (2020) Full text
CEFX/EFX Ultra SuperStim Pools: Superior positive controls for T-cell assays with broad MHC-allele and antigen coverage
Eckey et al. (2017) Full text
Developing Multi-HIV Antigen Specific T-Cells as a Component of a Cure Strategy
Lam et al. (2015) Full text
Peptide-stimulated Expansion of Virus-specific T cells For Preventative Treatment After Allogeneic Stem Cell Transplantation
Gary et al. (2015) Full text
PepMix™ Peptide Pools for Clinical Applications: T Cell Therapy for Viral Infections after Hematopoietic Stem Cell Transplant
Keirnan et al. (2012) Full text
Cytomegalovirus Protein Spanning PepMixTM Peptide Pools to Discover Changes in T-Cell Immunity in the Aging Population
Kern (2012) Full text

Testimonials
"To establish a novel role for myeloid derived suppressor cells (Pallett et al, Nat. Med. 2015) in chronic viral infection, we utilised the PepMix CEF Pool (extended) as well as a custom synthesized PepMix spanning the core region of HBV genotype D . Whereas, the CEF peptide pool consists of 32 peptides, each corresponding to a defined HLA class I-restricted T-cell epitope from Cytomegalo, Epstein-Barr, and Influenza virus, the latter custom PepMix included 15meric peptides overlapping by 10 amino acids. Specifically this composition enabled us to monitor both the antiviral CD8+ and CD4+ T cell responses in chronic HBV infection and the non-antigen specific T cells that are known to mediate immunopathology in the liver. Our entire experience with JPT, from ordering/delivery to use in the lab was excellent. Not only were the reagents able to perform reliably and consistently in vitro from batch to batch, the customer and technical support provided was continually available and efficient when needed. JPT will remain our go-to company for purchasing peptides."
Dr. Laura J Pallett, Infection and Immunity, University College London, UK

Documentation

Documentation for PepMix™ Collection BKV (2x1ug/peptide)

Properties

Properties of PepMix™ Collection BKV (2x1ug/peptide)

Properties Values
Amount: 2 x aliquots of each peptide pool (1µg /peptide /pool)
Application: T-cell immunity
Category: PepMix Peptide Pools
Condition / Topic: Infection, Merkel cell carcinoma, Nephritis, interstitial, Opportunistic infections
Layout: Freeze-dried in 1 x 96 tube rack
Organism: BK Polyomavirus (BKV)
Protein Name: Selected proteins
Purity: Development Grade: each peptide purified to > 70% (HPLC/MS)
Quantification: Yes

Further Information to PepMix™ Collection BKV (2x1ug/peptide)

Information Values
Sequence:
Collection of 7x 2 aliquots (a 1 ug/peptide) of each product. Product Code: PM-BKV-AGP PM-BKV-LTA PM-BKV-STA PM-BKV-VP1 PM-BKV-VP2 PM-BKV-VP3 PM-BKV-VP4
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