OVA 257-264 (SIINFEKL) is a well-characterized, immunodominant epitope derived from chicken ovalbumin protein (Uniprot P01012). This specific sequence, SIINFEKL, is frequently used in immunological assays due to its strong binding affinity to the H-2Kb molecule in MHC class I. Unlike complexes or dextramers, JPT's OVA antigen peptide is provided as a standalone peptide, which allows for broad applications in T cell assays such as ELISPOT, ICS, and cytotoxicity testing. Researchers often leverage OVA 257-264 in antibody production, epitope mapping, and the stimulation of antigen-specific CD8+ T cells to observe immune responses.
OVA (257-264) Chicken Ovalbumin Peptide - SIINFEKL - AA 257 - 264 for stimulation of antigen-specific T cells in T cell assays such as ELISPOT, ICS, cytotoxity or proliferation assays. CAS: 138831-86-4
OVA (257-264) Chicken Ovalbumin Peptide - SIINFEKL - Specifications
Amount: 1 mg
Purity: Trial Grade: each peptide purified to > 90% (HPLC/MS)
Delivery Format: Freeze-dried in plastic vial
Application(s): T-cell immunity
Condition(s)/Topic(s): Control, Infectious mononucleosis, Opportunistic infections
Standard Delivery Time: approx. 10 days
Applications of OVA257-264 (SIINFEKL) - CAS: 138831-86-4
- Stimulation of Antigen-Specific T Cells: Commonly used in assays to evaluate T cell functionality, the SIINFEKL epitope allows scientists to monitor CD8+ cytolytic responses with precision.
- Loading of Tetramers/Dextramers: Our peptide serves as an ideal component for T cell receptor (TCR) binding studies and the formation of multimer complexes for more advanced immune monitoring.
- Development of Immune Assays: By using SIINFEKL, scientists can perform ICS, ELISPOT, cytotoxicity, and proliferation assays with confidence.
- Antibody Production and Vaccine Development: Due to its strong immune response induction, the SIINFEKL peptide is valuable in preclinical studies focused on immunotherapy, vaccine trials, and epitope-based diagnostics.
Are you interested in your other antigen peptides? Choose your sequence, amount and purity. We will assist you along the way. Custom Peptide Synthesis.
JPT's Premium Antigen Peptides
At JPT Peptide Technologies, we offer a broad selection of antigen peptides like OVA (257-264), accompanied by PepMix™ Peptide Pools and MHC Multimers tailored for effective immune monitoring and therapeutic development. As a trusted partner in peptide synthesis, JPT is known for its precision-driven approach, ensuring peptides are synthesized with high purity and rigorously analyzed by HPLC-MS to validate identity and quality.
Advantages of Choosing JPT's Antigen Peptides
- Manufactured in Germany: All peptides, including OVA (257-264) with the sequence SIINFEKL, are produced under restricted regulations in Germany, ensuring the highest quality standards.
- Custom and Bulk Synthesis Options: We provide custom peptide synthesis upon request and offer bulk orders to accommodate high-throughput research needs.
- Purity and Safety: With synthesis protocols designed to prevent toxic contaminants and side products, our peptides maintain high safety and purity.
- Stability and Storage: Our peptides are delivered as freeze-dried aliquots, enhancing stability and making them suitable for long-term storage.
- Proven Performance: JPT's antigen peptides, have demonstrated efficacy in numerous clinical and preclinical studies.
.jpg "OVA (257-264) Chicken Ovalbumin Peptide - SIINFEKL")