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Osteogenic Growth Peptide (90-103), ALKRQGRTLYGFGG
SP-MHCI-0759-2

Osteogenic Growth Peptide (90-103), ALKRQGRTLYGFGG

US$169.00

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Description

About Osteogenic Growth Peptide (90-103), ALKRQGRTLYGFGG

What is Osteogenic Growth Peptide (OGP)?

Osteogenic Growth Peptide (OGP) is a naturally occurring, 14-amino-acid peptide fragment (ALKRQGRTLYGFGG) derived from the C-terminal region of histone H4. It plays a pivotal role in bone regeneration and remodeling by stimulating the proliferation and differentiation of osteoblasts, the cells responsible for bone formation. Because of its biological activity, OGP is widely studied as a bone healing peptide in preclinical and translational research, particularly in the context of tissue engineering, orthopedic recovery, and cancer-associated bone disorders.
Research suggests that OGP modulates T-cell immunity and may influence immune responses in bone metastasis, especially in cancers such as breast cancer. The combination of regenerative and immunomodulatory properties positions Osteogenic Growth Peptide as a valuable tool in both basic research and the development of therapeutic strategies

The Human Histones H4.1 Peptide (IEDB: 419495) is a high quality epitope peptide for stimulation of antigen-specific T cells in T cell assays such as ELISPOT, ICS, cytotoxicity or proliferation assays. The Histones Peptide, H-ALKRQGRTLYGFGG-OH (Uniprot: P62805 aa: 90-103) from JPT is produced under strict quality control and quality management.

Osteogenic Growth Peptide (90-103), ALKRQGRTLYGFGG - Specifications

  • Peptide sequence: H-ALKRQGRTLYGFGG-OH
  • Amount: 1 mg
  • Purity: Trial Grade: each peptide purified to > 90% (HPLC/MS)
  • Counterion: TFA
  • Delivery Format: Freeze-dried in plastic vial
  • Application(s): T-cell Immunity
  • Condition(s)/Topic(s): Breast cancer
  • Standard Delivery Time: approx. 3 weeks

Why Choose JPT's OGP?

JPT's Osteogenic Growth Peptide (OGP) is manufactured under stringent quality standards to ensure high purity and consistency. Each peptide batch is validated by HPLC-MS analysis, confirming its identity and structure, and delivered in a freeze-dried format for maximum stability and ease of handling.

Key Benefits:

  • Validated for immune applications, including T cell response studies
  • Free from toxic side products thanks to optimized synthesis protocols
  • Bulk and custom synthesis options available on request
  • Trusted for use in clinical studies and translational research
  • Scientific and responsive customer support

    • Researchers investigating bone healing peptides or exploring the immunological aspects of bone diseases and cancer can rely on JPT's OGP peptide for dependable results.

    References

    References for Osteogenic Growth Peptide (90-103), ALKRQGRTLYGFGG

    References:
    Read References with JPT’s Antigen Peptides
    Human Histone H4.1 90-103, ALKRQGRTLYGFGG has been described in:
    Early Kinetics of the HLA Class I-Associated Peptidome of MVA.HIVconsv-Infected Cells., J Virol, 2015 (PMID: 25810538)
    Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires., Immunogenetics, 2015 (PMID: 25502872)
    Immunological evaluation of individualized peptide vaccination with a low dose of estramustine for HLA-A24+ HRPC patients., Prostate, 2005 (PMID: 15378520)

    Documentation

    Documentation for Osteogenic Growth Peptide (90-103), ALKRQGRTLYGFGG


    Properties

    Properties of Osteogenic Growth Peptide (90-103), ALKRQGRTLYGFGG

    Properties Values
    Application: T-cell immunity
    Category: Antigen Peptides
    Condition / Topic: Breast cancer
    Layout: Freeze-dried in glass vial, Freeze-dried in plastic vial
    Organism: Human
    Protein Name: Histones
    Purity: Trial Grade: each peptide purified to > 90% (HPLC/MS)
    Quantification: No, Yes

    Further Information to Osteogenic Growth Peptide (90-103), ALKRQGRTLYGFGG

    Information Values
    Sequence: H-ALKRQGRTLYGFGG-OH
    Specifications: 14mer peptide as TFA salt
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