
Osteogenic Growth Peptide (90-103), ALKRQGRTLYGFGG
Description
About Osteogenic Growth Peptide (90-103), ALKRQGRTLYGFGG
What is Osteogenic Growth Peptide (OGP)?
Osteogenic Growth Peptide (OGP) is a naturally occurring, 14-amino-acid peptide fragment (ALKRQGRTLYGFGG) derived from the C-terminal region of histone H4. It plays a pivotal role in bone regeneration and remodeling by stimulating the proliferation and differentiation of osteoblasts, the cells responsible for bone formation. Because of its biological activity, OGP is widely studied as a bone healing peptide in preclinical and translational research, particularly in the context of tissue engineering, orthopedic recovery, and cancer-associated bone disorders.Research suggests that OGP modulates T-cell immunity and may influence immune responses in bone metastasis, especially in cancers such as breast cancer. The combination of regenerative and immunomodulatory properties positions Osteogenic Growth Peptide as a valuable tool in both basic research and the development of therapeutic strategieThe Human Histones H4.1 Peptide (IEDB: 419495) is a high quality epitope peptide for stimulation of antigen-specific T cells in T cell assays such as ELISPOT, ICS, cytotoxicity or proliferation assays. The Histones Peptide, H-ALKRQGRTLYGFGG-OH (Uniprot: P62805 aa: 90-103) from JPT is produced under strict quality control and quality management.
Osteogenic Growth Peptide (90-103), ALKRQGRTLYGFGG - Specifications
- Peptide sequence: H-ALKRQGRTLYGFGG-OH
- Amount: 1 mg
- Purity: Trial Grade: each peptide purified to > 90% (HPLC/MS)
- Counterion: TFA
- Delivery Format: Freeze-dried in plastic vial
- Application(s): T-cell Immunity
- Condition(s)/Topic(s): Breast cancer
- Standard Delivery Time: approx. 3 weeks
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JPT’s Antigen Peptides
Find your antigen peptide and select the connected PepMix™ Peptide Pool and MHC Multimer for efficient immune monitoring, mapping of T cell epitopes or development of immunotherapy and vaccines. JPT Peptide Technologies has substantial, long-standing expertise in providing peptides, peptidomimetics, and proteins to the global scientific community. Our highly skilled and committed scientific staff ensures that the most appropriate methods and techniques are selected for every synthesis project. All our catalog peptides are provided with HPLC-MS analyses to confirm the identity and demonstrate the high quality of our peptides.
References
References for Osteogenic Growth Peptide (90-103), ALKRQGRTLYGFGG
References:
Read References with JPT’s Antigen Peptides
Human Histone H4.1 90-103, ALKRQGRTLYGFGG has been described in:
Early Kinetics of the HLA Class I-Associated Peptidome of MVA.HIVconsv-Infected Cells., J Virol, 2015 (PMID: 25810538)
Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires., Immunogenetics, 2015 (PMID: 25502872)
Immunological evaluation of individualized peptide vaccination with a low dose of estramustine for HLA-A24+ HRPC patients., Prostate, 2005 (PMID: 15378520)
Documentation
Documentation for Osteogenic Growth Peptide (90-103), ALKRQGRTLYGFGG
Properties
Properties of Osteogenic Growth Peptide (90-103), ALKRQGRTLYGFGG
Properties | Values |
---|---|
Application: | T-cell immunity |
Category: | Antigen Peptides |
Condition / Topic: | Breast cancer |
Layout: | Freeze-dried in glass vial, Freeze-dried in plastic vial |
Organism: | Human |
Protein Name: | Histones |
Purity: | Trial Grade: each peptide purified to > 90% (HPLC/MS) |
Quantification: | No |
Further Information to Osteogenic Growth Peptide (90-103), ALKRQGRTLYGFGG
Information | Values |
---|---|
Sequence: | H-ALKRQGRTLYGFGG-OH |
Specifications: | 14mer peptide as TFA salt |