SP-CAT-004
Projects
NF-kB Inhibitor SN52 - translocation inhibitor is a variant of NF-kB Inhibitor SN50 and is a potent and cell-permeable inhibitor of NF-kB2 that blocks nuclear import of RelB:p52 dimer. NF-kB Inhibitor SN52 is used in cancer research as it sensitizes prostate cancer cells to ionizing radiation. It has also been shown to have less cytotoxicity to normal prostate epithelial cells compared to SN50. It is also a radiosensitizer used to prepare prostate cells for radiotherapy with DOTA or other radioligands.
One focus of JPT’s product development is oncology. Therefore, we offer a huge variety of TAA peptide, peptide pools and microarrays, as well as <DOTA peptides and radio sensitizers. JPT Peptide Technologies has substantial, long-standing expertise in providing peptides in all formats, scales and modifications to the global scientific community. All our catalog peptides are provided with HPLC-MS analyses to confirm the identity and demonstrate the high quality of our peptides.Have a look at our Peptide Tools to Study Cancer.
Benefits of JPT’s PeptidesReferences:
Read References with Specialty Peptides
Testimonial:
"Our group focuses on the in vitro study of risk factors in Alzheimer’s disease and, as we experienced that the in-house expression and production of the amyloid beta peptide is notoriously difficult, we are continuously dependent on a high quality supply of a large variety of these peptides from commercial source.We started our collaboration with JPT with their request to test a range of their peptides for the ability to produce toxic oligomers and fibrillar networks and were impressed by the rapid supply of a very wide range of high purity peptides with excellent fibril forming properties and toxicity profiles. JPT has shown real valuable know-how and experience in the field of peptide synthesis by their ability to generate high quality preparations of amyloid beta peptide variants which are known for their difficulty to handle."
Kerensa Broersen, Assistant Prof., Nanobiophysics Group, University of Twente, Enschede, The Netherlands
Testimonial:
Our group focuses on the in vitro study of risk factors in Alzheimer’s disease and, as we experienced that the in-house expression and production of the amyloid beta peptide is notoriously difficult, we are continuously dependent on a high quality supply of a large variety of these peptides from commercial source.We started our collaboration with JPT with their request to test a range of their peptides for the ability to produce toxic oligomers and fibrillar networks and were impressed by the rapid supply of a very wide range of high purity peptides with excellent fibril forming properties and toxicity profiles. JPT has shown real valuable know-how and experience in the field of peptide synthesis by their ability to generate high quality preparations of amyloid beta peptide variants which are known for their difficulty to handle.
Kerensa Broersen, Assistant Prof., Nanobiophysics Group, University of Twente, Enschede, The Netherlands
| Properties | Values |
|---|---|
| Amount: | 1 mg |
| Application: | Nuclear medicine |
| Category: | Single Peptide |
| Condition / Topic: | Cancer |
| Layout: | Freeze-dried in plastic vial |
| Organism: | Artificial |
| Protein Name: | Radio sensitizer |
| Purity: | Trial Grade: each peptide purified to > 90% (HPLC/MS) |
| Quantification: | Yes |
| Information | Values |
|---|---|
| Sequence: | H-AAVALLPAVLLALLAPVQRKRRKALP-OH |
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