SP-CAT-003
Projects
SN50 peptide is a highly potent inhibitor of NF-kB. SN50 peptide consists of the hydrohobic region of K-FGF Kaposi’s fibroblast growth factor (NF-KB) fused to the NLS sequence of NF-kB p50. The SN50 peptide enters cells and inhibits the translocation of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) into the nucleus. It is also a radiosensitizer used to prepare prostate cells for radiotherapy with DOTA or other radioligands.
One focus of JPT’s product development is oncology. Therefore, we offer a huge variety of TAA peptide, peptide pools and microarrays, as well as <DOTA peptides and radio sensitizers. JPT Peptide Technologies has substantial, long-standing expertise in providing peptides in all formats, scales and modifications to the global scientific community. All our catalog peptides are provided with HPLC-MS analyses to confirm the identity and demonstrate the high quality of our peptides.Have a look at our Peptide Tools to Study Cancer.
Benefits of JPT’s PeptidesReferences:
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Testimonial:
Our group focuses on the in vitro study of risk factors in Alzheimer’s disease and, as we experienced that the in-house expression and production of the amyloid beta peptide is notoriously difficult, we are continuously dependent on a high quality supply of a large variety of these peptides from commercial source.We started our collaboration with JPT with their request to test a range of their peptides for the ability to produce toxic oligomers and fibrillar networks and were impressed by the rapid supply of a very wide range of high purity peptides with excellent fibril forming properties and toxicity profiles. JPT has shown real valuable know-how and experience in the field of peptide synthesis by their ability to generate high quality preparations of amyloid beta peptide variants which are known for their difficulty to handle.
Kerensa Broersen, Assistant Prof., Nanobiophysics Group, University of Twente, Enschede, The Netherlands
Properties | Values |
---|---|
Amount: | 1 mg |
Application: | Nuclear medicine |
Category: | Single Peptide |
Condition / Topic: | Cancer |
Layout: | Freeze-dried in plastic vial |
Organism: | Artificial |
Protein Name: | Radio sensitizer |
Purity: | Trial Grade: each peptide purified to > 90% (HPLC/MS) |
Quantification: | Yes |
Information | Values |
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Sequence: | H-AAVALLPAVLLALLAPVQRKRQKLMP-OH |
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