Building ProteomeTools Based on a Complete Synthetic Human Proteome

Zolg et al., Nature Methods (2017) - PMID: 28135259

Product(s) used in this publication:  SpikeTides™ - Proteomics Peptide Standards


We describe ProteomeTools, a project building molecular and digital tools from the human proteome to facilitate biomedical research. Here we report the generation and multimodal liquid chromatography-tandem mass spectrometry analysis of >330,000 synthetic tryptic peptides representing essentially all canonical human gene products, and we exemplify the utility of these data in several applications. The resource (available at will be extended to >1 million peptides, and all data will be shared with the community via ProteomicsDB and ProteomeXchange.

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