KALA Amphipathic Peptide is a cationic amphipathic cell penetrating peptide (CPP) that can be used as a cargo delivery system across cell membranes and to study intracellular processes. KALA peptide is able to form an a-helix at pH is 7.5. It can bind DNA and destabilize cell membranes. Therefore, it can facilitate the delivery of DNA and is used in DNA transfection. It can be used for effective liver targeting and transfection of DNA via galactose receptors. Described by Wyman et al. 1997.
KALA Amphipathic Peptide - Specifications
- Peptide sequence: H-WEAKLAKALAKALAKHLAKALAKALKA-OH
- Amount: 1 mg
- Purity: Trial Grade: each peptide purified to > 90% (HPLC/MS)
- Counterion: TFA
- Delivery Format: Freeze-dried in plastic vial
- MW (average): 2828.51
- Application(s): Drug delivery
- Condition(s)/Topic(s): Cancer, Gene therapy
- Standard Delivery Time: 2-5 days
- CAS: 187987-64-0
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JPT’s Cell Penetrating Peptides – CPPs
Cell Penetrating Peptides (CPPs) are capable of crossing cellular membranes, facilitating the delivery of various therapeutic and experimental cargoes, such as bioactive molecules, into cells. Their ability to transport molecules that otherwise cannot penetrate cell membranes, such as proteins, peptides, and even large nucleic acids like plasmid DNA or RNA, makes them indispensable for both fundamental research and clinical applications. JPT Peptide Technologies has substantial, long-standing expertise in providing peptides in all formats, scales and modifications to the global scientific community. All our catalog peptides are provided with HPLC-MS analyses to confirm the identity and demonstrate the high quality of our peptides.
Benefits of JPT’s Peptides- All peptides are made in Germany
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- Provision of freeze-dried aliquots for enhanced stability
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