SP-MHCI-1244-2

Insulin, isoform 2 3-11, LWMRLLPLL

US$169.00

Limited stock

Description

About Insulin, isoform 2 3-11, LWMRLLPLL

The Human Insulin isoform 2 Peptide (IEDB: 105950) is a high quality epitope peptide for stimulation of antigen-specific T cells in T cell assays such as ELISPOT, ICS, cytotoxicity or proliferation assays. The Insulin Peptide, H-LWMRLLPLL-OH (Uniprot: F8WCM5 aa: 3-11) from JPT is produced under strict quality control and quality management.

Insulin, isoform 2 3-11, LWMRLLPLL - Specifications

  • Peptide sequence: H-LWMRLLPLL-OH
  • Amount: 1 mg
  • Purity: Trial Grade: each peptide purified to > 90% (HPLC/MS)
  • Counterion: TFA
  • Delivery Format: Freeze-dried in glass vial
  • Application(s): T-cell Immunity
  • Condition(s)/Topic(s): Diabetes
  • Standard Delivery Time: approx. 3 weeks

JPT’s Antigen Peptides
Find your antigen peptide and select the connected PepMix™ Peptide Pool for efficient immune monitoring, mapping of T cell epitopes or development of immunotherapy and vaccines. JPT Peptide Technologies has substantial, long-standing expertise in providing peptides, peptidomimetics, and proteins to the global scientific community. Our highly skilled and committed scientific staff ensures that the most appropriate methods and techniques are selected for every synthesis project. All our catalog peptides are provided with HPLC-MS analyses to confirm the identity and demonstrate the high quality of our peptides.
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Benefits of JPT’s Antigen Peptides
- All peptides are made in Germany
- Bulk orders or custom peptide snythesis upon request
- Synthesis protocols designed to avoid toxic contaminants and side products
- Provision of freeze dried aliquots for enhanced stability
- Proven track record for applications in clinical studies
- Order the connected PepMix™ Peptide Pool with your peptide!

References

References for Insulin, isoform 2 3-11, LWMRLLPLL

References:
Read References with JPT’s Antigen Peptides

Insulin, isoform 2 3-11, LWMRLLPLL has been described in:
Circulating preproinsulin signal peptide-specific CD8 T cells restricted by the susceptibility molecule HLA-A24 are expanded at onset of type 1 diabetes and kill β-cells., Diabetes, 2012 (PMID: 22522618.0)
Human β-cell killing by autoreactive preproinsulin-specific CD8 T cells is predominantly granule-mediated with the potency dependent upon T-cell receptor avidity., Diabetes, 2013 (PMID: 22936177.0)
Molecular Pathways for Immune Recognition of Preproinsulin Signal Peptide in Type 1 Diabetes., Diabetes, 2018 (PMID: 29343547.0)

Documentation

Documentation for Insulin, isoform 2 3-11, LWMRLLPLL

Properties

Properties of Insulin, isoform 2 3-11, LWMRLLPLL

Properties Values
Application: T-cell immunity
Category: Antigen Peptides
Condition / Topic: Diabetes
Layout: Freeze-dried in glass vial
Organism: Human
Protein Name: Insulin
Purity: Trial Grade: each peptide purified to > 90% (HPLC/MS)
Quantification: No

Further Information to Insulin, isoform 2 3-11, LWMRLLPLL

Information Values
Sequence: H-LWMRLLPLL-OH
Specifications: 9mer peptide as TFA salt
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