SP-MHCI-1244-2
The Human Insulin isoform 2 Peptide (IEDB: 105950) is a high quality epitope peptide for stimulation of antigen-specific T cells in T cell assays such as ELISPOT, ICS, cytotoxicity or proliferation assays. The Insulin Peptide, H-LWMRLLPLL-OH (Uniprot: F8WCM5 aa: 3-11) from JPT is produced under strict quality control and quality management.
JPT’s Antigen Peptides
Find your antigen peptide and select the connected PepMix™ Peptide Pool for efficient immune monitoring, mapping of T cell epitopes or development of immunotherapy and vaccines. JPT Peptide Technologies has substantial, long-standing expertise in providing peptides, peptidomimetics, and proteins to the global scientific community. Our highly skilled and committed scientific staff ensures that the most appropriate methods and techniques are selected for every synthesis project. All our catalog peptides are provided with HPLC-MS analyses to confirm the identity and demonstrate the high quality of our peptides.
Not found what you are looking for? Take a look at our Custom Peptide Synthesis!
Benefits of JPT’s Antigen Peptides
- All peptides are made in Germany
- Bulk orders or custom peptide snythesis upon request
- Synthesis protocols designed to avoid toxic contaminants and side products
- Provision of freeze dried aliquots for enhanced stability
- Proven track record for applications in clinical studies
- Order the connected PepMix™ Peptide Pool with your peptide!
References:
Read References with JPT’s Antigen Peptides
Insulin, isoform 2 3-11, LWMRLLPLL has been described in:
Circulating preproinsulin signal peptide-specific CD8 T cells restricted by the susceptibility molecule HLA-A24 are expanded at onset of type 1 diabetes and kill β-cells., Diabetes, 2012 (PMID: 22522618.0)
Human β-cell killing by autoreactive preproinsulin-specific CD8 T cells is predominantly granule-mediated with the potency dependent upon T-cell receptor avidity., Diabetes, 2013 (PMID: 22936177.0)
Molecular Pathways for Immune Recognition of Preproinsulin Signal Peptide in Type 1 Diabetes., Diabetes, 2018 (PMID: 29343547.0)
Properties | Values |
---|---|
Application: | T-cell immunity |
Category: | Antigen Peptides |
Condition / Topic: | Diabetes |
Layout: | Freeze-dried in glass vial |
Organism: | Human |
Protein Name: | Insulin |
Purity: | Trial Grade: each peptide purified to > 90% (HPLC/MS) |
Quantification: | No |
Information | Values |
---|---|
Sequence: | H-LWMRLLPLL-OH |
Specifications: | 9mer peptide as TFA salt |
Check our list of products, click and go.
Get a quote