Monitoring of Immune Responses

JPT’s immune  monitoring tools and services for high resolution profiling of cellular and humoral immune response target specific antigens or antigen families. This allows monitoring of individual epitope patterns as well as epitope spreading and address natural sequence diversity, mutations and post-translational modifications that occur in cancer cells and different types of viruses.
The combination of technical and bioinformatic knowledge provides efficient epitope resolved profiling of cellular immune responses that can be correlated to clinical data.

Cellular Immune Response Profiling:

PepMix™ Peptide Pools

Our widely used PepMixes™ are available in a large variety of off-the-shelf peptide pools (e.g. for EBV, HCMV, Adenovirus, BKV, HHV6 and tumor associated antigens) or tailored for your specific application and antigen. We also offer a wide variety of standardization and control pools such as CEF Pools and HCMV (pp65).
> PepMix™ Peptide Pools

MHC Multimers for Detection of Antigen-Specific T cells

MHC Multimers are used for detection, enumeration and isolation of antigen-specific T cells in fluid cell samples (PBMC, blood) by flow cytometry.
> MHC Multimers

Humoral Immune Response Profiling:

PepStar™ Peptide Microarrays

Our customized peptide microarrays profiling of cancer specific samples or antibodies, detection of epitopes and epitope spreading and vaccine target identification. Our peptide microarrays display overlapping peptide scans through antigens, or selected amino acid sequences. You define content and layout, we provide economic and fast production in our regulated clean-room environment. We also offer our assay and analysis service using your samples with your tailored peptide microarray.
> PepStar™ Peptide Microarrays

Peptide ELISA

We offer customized peptide-coated ELISA plates (enzyme-linked immunosorbent assay). ELISA is a well established analytical and highly sensitive immunological assay for proteins but requires detailed experimental know-how for peptides. Peptide ELISA is used for mapping of epitopes and definition of protein interaction sites or as validation assay to confirm results obtained with JPT’s peptide microarrays.
>Peptide ELISA

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