EBV BZLF1 190-197 Peptide (HLA-B*08:01) - RAKFKQLL
Description
About EBV BZLF1 190-197 Peptide (HLA-B*08:01) - RAKFKQLL
The Epstein-Barr Virus (EBV) BZLF1 Trans-activator protein Peptide is a high quality epitope peptide for stimulation of antigen-specific T cells in T cell assays such as ELISPOT, ICS, cytotoxicity or proliferation assays. The BZLF1 Trans-activator protein Peptide, H-RAKFKQLL-OH (Uniprot: P03206 aa: 190-197) from JPT is produced under strict quality control and quality management.
EBV BZLF1 190-197 Peptide (HLA-B*08:01) - RAKFKQLL - Specifications
- Peptide sequence: H-RAKFKQLL-OH
- Amount: 1 mg
- Purity: Trial Grade: each peptide purified to > 90% (HPLC/MS)
- Delivery Format: Freeze-dried in plastic vial
- Application(s): T-cell immunity
- Condition(s)/Topic(s): Autoimmune disease, Burkitt's lymphoma, Hodgkin's lymphoma, Nasopharyngeal carcinoma, Infectious mononucleosis
- Standard Delivery Time: approx. 10 days
Visit our webpage for more information on Peptide Tools to Study EBV
Applications
The BZLF1 190-197 peptide is one of the most extensively studied EBV-derived CD8+ T-cell epitopes and plays a central role in immune recognition of EBV-infected cells. It is considered an immunodominant epitope in individuals expressing HLA-B*08:01 and is frequently used in:
- ELISpot assays for IFN-Y detection
- Intracellular cytokine staining (ICS)
- Tetramer-based immune monitoring
- Adoptive T-cell therapy research
Due to its strong and reproducible immunogenicity, the RAKFKQLL peptide is widely used as a reference epitope in EBV-specific immune response studies.
Why Choose JPT?
- High expertise in peptide synthesis for immunology research
- Consistent quality and reproducibility
- Optimized for T-cell assays and immunomonitoring
- Trusted partner in viral immunology and oncology research
Custom Antigen Peptide Services
In addition to the EBV BZLF-1 190-197, JPT offers comprehensive custom antigen peptide synthesis services tailored to your research needs.
Researchers can request:
- Custom peptide sequences
- Modified peptides (e.g. phosphorylation, labeling)
- Different purity grades and scales
- Peptides optimized for T-cell assays and immunomonitoring
Our expertise ensures high-quality peptides suitable for immunology, oncology, and infectious disease research.
Scrambled Antigen Peptide Controls
For experimental validation, JPT also provides scrambled versions of antigen peptides, including sequences derived from BZLF1 190-197 (RAKFKQLL).
Scrambled peptides are commonly used as:
- Negative controls in T-cell assays
- Controls for specificity and background signal
- Validation tools in ELISpot, ICS, and cytotoxicity assays
These control peptides help ensure accurate interpretation of EBV-specific immune responses.
References
References for EBV BZLF1 190-197 Peptide (HLA-B*08:01) - RAKFKQLL
References:Read References with Antigen Peptides
Also, take a look at these studies in which the RAKFKQLL peptide produced by JPT was used:
- Lammoglia Cobo, Maria Fernanda, et al. "Reconstitution of EBV-directed T cell immunity by adoptive transfer of peptide-stimulated T cells in a patient after allogeneic stem cell transplantation for AITL." PLOS Pathogens 18.4 (2022): e1010206.
- ElAbd, Hesham, et al. "T and B cell responses against Epstein-Barr virus in primary sclerosing cholangitis." Nature Medicine 31.7 (2025): 2306-2316.
Documentation
Documentation for EBV BZLF1 190-197 Peptide (HLA-B*08:01) - RAKFKQLL
Properties
Properties of EBV BZLF1 190-197 Peptide (HLA-B*08:01) - RAKFKQLL
| Properties | Values |
|---|---|
| Application: | T-cell immunity |
| Category: | Antigen Peptides |
| Condition / Topic: | Autoimmune disease, Burkitt's lymphoma, Hodgkin's lymphoma, Infectious mononucleosis, Nasopharyngeal carcinoma |
| Layout: | Freeze-dried in plastic vial |
| Organism: | Epstein-Barr Virus (EBV) |
| Protein Name: | BZLF1 Trans-activator protein |
| Purity: | Trial Grade: each peptide purified to > 90% (HPLC/MS) |
| Quantification: | No |
Further Information to EBV BZLF1 190-197 Peptide (HLA-B*08:01) - RAKFKQLL
| Information | Values |
|---|---|
| Sequence: | H-RAKFKQLL-OH |
| Specifications: | 8mer peptide as TFA salt |
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