EBV BMLF1 280-288 Peptide (HLA-A*02:01) - GLCTLVAML

The EBV BMLF1 280-288 peptide (GLCTLVAML) is a well-characterized HLA-A*02:01-restricted CD8+ T cell epitope derived from the Epstein-Barr virus (EBV) early lytic protein BMLF1. Recognized as one of the most immunodominant EBV epitopes, GLCTLVAML is widely used in immunological research to monitor and quantify EBV-specific cytotoxic T lymphocyte (CTL) responses. This peptide plays a critical role in studies of viral immunity, vaccine development, and T cell-based immunotherapies targeting EBV-associated diseases.

The Epstein-Barr Virus (EBV) BMLF1 (mRNA export factor EB2) Peptide is a high quality epitope peptide for stimulation of antigen-specific T cells in T cell assays such as ELISPOT, ICS, cytotoxicity or proliferation assays. The BMLF1 (mRNA export factor EB2) Peptide, H-GLCTLVAML-OH (Uniprot: Q04360 aa: 300-308) from JPT is produced under strict quality control and quality management.

EBV BMLF1 280-288 Peptide (HLA-A*02:01) - GLCTLVAML - Specifications

• Peptide sequence: H-GLCTLVAML-OH
• Amount: 1 mg
• Purity: Trial Grade: each peptide purified to > 90% (HPLC/MS)
• Delivery Format: Freeze-dried in plastic vial
• Application(s): T-cell immunity
• Condition(s)/Topic(s): Autoimmune disease, Burkitt's lymphoma, Hodgkin's lymphoma, Nasopharyngeal carcinoma, Infectious mononucleosis
• Standard Delivery Time: approx. 10 days

Visit our webpage for more information on Peptide Tools to Study EBV

Applications

• Detection of EBV-specific CD8+ T cells using flow cytometry and tetramer staining
• Functional T cell assays such as ELISPOT, intracellular cytokine staining (ICS), and cytotoxicity assays
• T cell proliferation and activation studies
• Immune monitoring in EBV-associated diseases
• Expansion of antigen-specific T cells in vitro
• Vaccine and immunotherapy research targeting EBV

Quality & Manufacturing Excellence

• High purity peptide (>90%) confirmed by HPLC and mass spectrometry
• Strict quality control and manufacturing standards (Made in Germany)
• Reliable performance in sensitive immunological assays
• Lyophilized format for stability and long-term storage
• Optimized synthesis minimizing impurities and batch variability

Custom & Scrambled Versions Available

Need a scrambled GLCTLVAML peptide?

We offer custom scrambled variants of the EBV BMLF-1 280-288 sequence, carefully validated to ensure:

• No overlap with natural proteins (UniProt cross-check)
• Reliable use as negative controls in T cell assays

Custom sequence modifications, purity upgrades, and bulk orders are available upon request.

JPT’s Antigen Peptides
Find your antigen peptide and select the connected PepMix™ Peptide Pool and MHC Multimer for efficient immune monitoring, mapping of T cell epitopes or development of immunotherapy and vaccines. JPT Peptide Technologies has substantial, long-standing expertise in providing peptides, peptidomimetics, and proteins to the global scientific community. Our highly skilled and committed scientific staff ensures that the most appropriate methods and techniques are selected for every synthesis project. All our catalog peptides are provided with HPLC-MS analyses to confirm the identity and demonstrate the high quality of our peptides.

Benefits of JPT’s Antigen Peptides
- All peptides are made in Germany
- Bulk orders or custom peptide snythesis upon request
- Synthesis protocols designed to avoid toxic contaminants and side products
- Provision of freeze dried aliquots for enhanced stability
- Proven track record for applications in clinical studies
- Order the connected PepMix™ Peptide Pool with your peptide!