The Brain natriuretic peptide 32 (BNP-32), Human is a high quality natriuretic peptide for cardiovascular research. Also called Nesiritide, it shows vasodilatory, diuretic, and natriuretic activities. However, the main source of this peptide is not the brain but the cardiac ventricle. This cardiac neurohormone is secreted from the ventricles in response to volume expansion and pressure overload. It has natriuretic and vasodilatory effects and suppresses the renin-angiotensin-aldosterone system. The Brain natriuretic peptide 32 (BNP-32), Human , H-SPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH-OH (C10-C26 disulfide bond) from JPT is produced under strict quality management.
Brain natriuretic peptide 32 (BNP-32), Human - Specifications
- Peptide sequence: H-SPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH-OH (C10-C26 disulfide bond)
- Amount: 0.5 mg
- Purity: >95% (HPLC/MS)
- Counterion: TFA
- Delivery Format: Freeze-dried in plastic vial
- Application(s): Cardiovascular Research
- Condition(s)/Topic(s): Electrolyte balance, cardiovascular disease
- Standard Delivery Time: approx. 3 weeks
Are you interested in other natriuretic peptides?Choose sequence, amount and purity. We will assist you along the way: Custom Peptide Synthesis
Natriuretic Peptides from JPT
Natriuretic peptides are peptide hormones that regulate the cardiovascular system. Natriuretic peptides display strong diuretic, natriuretic, and vasodilatory effects. These peptide hormones are regulating blood pressure, fluid-electrolyte balance, and cardiovascular function and are involved in inflammation, and apoptosis. As they are activated during heart failure, a major clinical application of natriuretic peptides is diagnosing heart failure.
There are five types of natriuretic peptides:
- Atrial natriuretic peptide (ANP)
- Brain natriuretic peptide (BNP)
- C-type natriuretic peptide (CNP)
- Urodilatin (URO)
- Dendroaspis natriuretic peptide (DNP)
Benefits of JPT’s Natriuretic Peptides
- Each peptide quality controlled and guaranteed for identity and purity
- CoA and HPLC-MS data available
- High batch-to-batch consistency
- Synthesis protocols designed to avoid toxic contaminants and side products
- Provision of freeze dried aliquots for enhanced stability
- Proven track record for applications in clinical studies
