Sometimes, a peptide sequence is only the beginning.
Beyond immunization and proteomics assays, modified and specialty peptides offer a range of applications: a fluorescent label can turn a peptide into a tool for visualization. A biotin tag can enable capture and detection. Post-translational modifications can help researchers investigate complex biological processes, while cyclization, non-natural amino acids, isotope labels, and other modifications can open up entirely different experimental possibilities.
At JPT, we combine expertise in peptide synthesis with a broad range of specialty peptides and peptide modifications, enabling researchers to design peptides around the needs of their experiments.
But what do they look like in action?
Scientific publications provide some of the best examples. Across diverse areas of research, modified and specialty peptides are being used as tools for detection, quantification, interaction studies, assay development, structural investigations, and the exploration of biological mechanisms. Take a look at multiple examples of publications and papers having made use of our modified peptides.
Biotinylated & Tagged Peptides
Introduce affinity or detection tags to support applications such as binding studies, peptide capture, immobilization, and assay development.
- Dengue antibody dynamics resolved at epitope level using a dengue 1 human infection model
Bouckaert et al., International Journal of Infectious Diseases (2026) - Defining the cross-reactivity between peanut allergens Ara h 2 and Ara h 6 using monoclonal antibodies
Marini-Rapoport et al., Clinical & Experimental Immunology (2024)
Fluorescent Dye-Labeled Peptides
Combine peptides with fluorescent reporters for applications ranging from detection and localization to binding and uptake studies. Examples include FRET of fluorescent imaging.
- Mechanistic Divergence and Diferential Antibacterial Potency of the Proline‑Rich Antimicrobial Peptide B7‑005 Across ESKAPE +E Pathogens
Di Stasi et al., Probiotic & Antimicrobial Proteins (2025) - Extracellular vesicle surface engineering with integrins (ITGAL & ITGB2) to specifcally target ICAM-1-expressing endothelial cells
Bergqvist et al., Journal of Nanobiotechnology (2025)
Isotope-Labeled Peptides
Generate defined reference peptides for quantitative applications, including targeted mass spectrometry and proteomic workflows.
- Quantification of Human Cardiac Ion Channels by Parallel Reaction Monitoring and In-Sample Calibration
Torkamannejad et al., ACS Omega (2026) - Amylase/trypsin inhibitors (ATIs) levels in wheat event IND‑ØØ412‑7 are similar to non‑transgenic wheat
Ferela et al., Transgenic Research (2026)
Peptide Dimers & Cyclic Peptides
Explore peptide architectures beyond the linear sequence, including constructs designed for multivalent interactions, conformational constraints, or increased stability.
- The V2 domain of HIV gp120 mimics an interaction between CD4 and integrin ⍺4β7
Van Ryk et al., PLoS Pathogens (2023) - DNA tools for Imaging and Manipulation of Biological Samples
Baars, Dissertation (2024)
Post-Translationally Modified Peptides
Study biologically relevant modifications with peptides carrying phosphorylation, glycosylation, and other post-translational modifications.
- Only bioactive forms of PTH (n‑oxPTH and Met18(ox)‑PTH) inhibit synthesis of sclerostin – evidence from in vitro and human studies
Li et al., European Journal of Physiology (2024) - Decrypting lysine deacetylase inhibitor action and protein modifications by dose-resolved proteomics
Chang et al., Cell Reports (2024)
Peptides with Unnatural Amino Acids
Expand beyond the 20 proteinogenic amino acids to introduce additional chemical functionalities or investigate the effects of defined structural changes.
Peptidomimetics
Introduce structural elements that mimic peptide characteristics while allowing researchers to investigate alternative molecular properties and interactions.
Click Chemistry Peptides
Incorporate click-compatible functionalities to enable selective conjugation of peptides with other molecules, labels, or surfaces.
Take a look at our other references, or contact our experienced customer support team for inquiries.