We do so much more! Bionconjugated Peptides

At JPT, we offer a complete conjugation service designed to meet your specific research needs. Leveraging our extensive experience, we provide: 

Custom Conjugation Chemistry!

We help you select the most suitable conjugation chemistry: 

• Click Chemistry: Copper or copper-free with alkyne-azide, or DBCO-azide reaction 
• Maleimide-thiol 
• NHS Ester-amine 
• Crosslinkers (EDC, glutaralydehyde, SMCC…) 

Our Conjugate Selection: 

Protein Conjugation:

Protein conjugates enhance antibody generation by linking peptides to carrier proteins (e.g. KLH, BSA, OVA, HAS) via thiol-maleimide chemistry, followed by dialysis to remove non-specific peptides. Alternatively, multiple antigenic peptides (MAPs) use a lysine core to present peptides without carriers, effectively stimulating immunity. Find more information on our website! 

Lipid Conjugation 

Lipid-peptide conjugation enhances biological activity, membrane affinity, cellular uptake, stability, or immune stimulatory potential. Typically, lipidation occurs at the peptide’s N-terminus or side chain via thiol chemistry or amide bond formation. Common examples include: 

• Fatty acids (e.g. palmitic acid, myristic acid, etc.) 
• PEG-lipid conjugates -GPI-like anchors 
• Pam2Cys / Pam3Cys 
• Semaglutides and liraglutides

Oligonucleotide Conjugation 

Peptide-oligonucleotide conjugates improve drug delivery by enhancing oligonucleotide stability, uptake, and targeting. Cell-penetrating peptides enable receptor-mediated endocytosis and support gene modulation for therapy. 

Other Molecules 

Want to conjugate drugs or any other molecules with our peptides? Contact us! Find more information on peptide conjugates on our website! 

Our Selected References: 

• PepH3-modified nanocarriers for delivery of therapeutics across the blood-brain barrier
  Szecskó et al., Fluids and Barrier of the CNS (2025) – PMID: 40170024 
• The N-terminal Proline Hinge Motif Controls the Structure of Bovine Herpesvirus 1-encoded Inhibitor of the Transporter Associated with Antigen Processing Required for its Immunomodulatory Function
  Graul et al., Journal of Molecular Biology (2023) – PMID: 36646375 
• Sulfated Lactosyl Archaeol Archaeosome-Adjuvanted Vaccine Formulations Targeting Rabbit Hemorrhagic Disease Virus Are Immunogenic and Efficacious
  Akache et al., Vaccines (2023) – PMID: 37376432 
• Optimizing Mechanostable Anchor Points of Engineered Lipocalin in Complex With CTLA-4
  Liu et al., BioRxiv (2021)