JPT's Peptide Tools to monitor the current Ebola outbreak in Uganda

Published on 01/11/2022

The European Center for Disease Control is currently closely monitoring a yet relatively small outbreak of Ebola in the Mubende District in Uganda. The outbreak is attributed to a strain belonging to a Sudan-type species. The licensed vaccines protect against disease caused by the Zaire ebolavirus (ZEBOV); however, vaccines protecting against the Sudan ebolavirus (SUDV) and data on the level of cross immunities are not available yet. 

Our PepMix Peptide Pools are useful for a variety of applications to monitor and study the current outbreak: 

  • Antigen-specific T-cell stimulation in T cell assays (e.g. ELISpot, or proliferation assays)
  • In-vitro T-cell expansion
  • Cellular immune response profiling
  • T-cell epitope identification 

 It is noteworthy, that the spike glycoprotein (GP) of ZEBOV shares a sequence homology of >97.5 % with the current species, whereas the SUDV meets a sequence homology not higher than 54% with the current virus of interest. 

Our available catalog PepMix Peptide Pools: 

We also offer custom PepMix peptide pools and PepStar Peptide Microarrays for cellular and humoral immune monitoring, respectively. Moreover, as the provider of the largest variety of peptide formats, we invite you to take a look at our other custom options, and we will tailor your research tools according to your specifications. 
If you have questions, please do not hesitate to contact our experienced customer support team.      

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