Explore our PepMix™ Catalog: Monitoring Immune Responses to Viral, Bacterial & Tumor-associated Antigens!

With over 500 products, the PepMix™ Peptide Pool Catalog is the most comprehensive on the market. We offer a wide variety of different pools for immune monitoring, cellular immune response profiling, or T cell epitope identification via T Cell Assays. 

Today, we are highlighting our catalog PepMix™ Peptide Pools covering infectious disease antigens, tumor-associated antigens (TAAs) and more. 

PepMix™ covering Tumor Associated Antigens (TAA) 

Peptides covering TAAs play a pivotal role in cancer therapy, including adoptive cell therapy development and cancer vaccines. While tumor antigens are larger proteins, the epitopes eliciting an immune response by T cells contain short peptide sequences represented by our overlapping peptide pools. JPT offers more than 70 TAA-specific peptide pools for a wide range of cancer types, including: 

• Melanoma-associated antigens: MAGE A, C, D, Melan-A, Tyrosinase … 
• Breast, prostate-, gastric-, genital-, and … cancer associated antigens: TERT, ErbB2, Mammaglobin A, Mucin-1, NY-ESO-1-2, PAP, PSA, PSCA, PSMA … 
• Leukemia: KRAS 

Selected Publications for PepMix™ TAAs: 

1. Circulating tumor-associated antigen-specific IFN? + 4-1BB + CD8 + T cells as peripheral biomarkers of treatment outcomes in patients with pancreatic cancer
   Murakami et al., Frontiers in Immunology (2024) – PMID: 38550601
   Products used: PepMix Human (CEA), Human (TERT), Human (WT1/WT33), Human (Mucin-1) 
2. Multimodal single-cell profiling of T lymphocytes in infection and cancer
   Bieberich, Dissertation (2024)
   Products used: PepMix Human (CEA), Human (MAGEA3), Human (NY-ESO-2), Human (WT1/WT33) 
3. Prophylactic Vaccination and Intratumoral Boost with HER2-Expressing Oncolytic Herpes Simplex Virus Induces Robust and Persistent Immune Response against HER2-Positive Tumor Cells
   Delwar et al., Vaccines (2023)
   Product used: PepMix Human (ErbB2_ECD) 

Find more references on our website. 

PepMix™ for Viral, Bacterial and Parasitical Vectors 

Monitoring the immune response before and after immunization, through infection or vaccination is key to combating or preventing infectious diseases. JPT has accumulated more than 300 PepMix™ peptide pools covering a wide range of infectious diseases antigens, including: 

• Coronaviruses: SARS-CoV-2, SARS-CoV-1, MERS, H-CoV 
• Vector-borne diseases such as Flaviviridae: Zika, Dengue, West Nile, Yellow Fever 
• Tropical diseases: Chikungunya, Crimean-Congo Hemorrhagic Fever, Ebola, Lassa Hemorrhagic Fever, Malaria, Marburg virus, Nipah virus
• Poxviridae: Cowpox, Monkeypox, Rabbitpox, Smallpox, Vaccinia 
• Adenoviruses 
• Borrelia 
• Epstein–Barr virus (EBV) 
• Human Cytomegalovirus (H-CMV) 
• Human Immunodeficiency Virus (HIV) 
• Human Papillomavirus (HPV) 
• Influenza (A&B) 
• Tuberculosis 
• Measles 
• Respiratory Syncytial Virus (RSV) 
• Rotavirus 
• Rubella Virus 
• Varicella-Zoster Virus (VZV) 

Selected Publications for PepMix™ Infectious Diseases: 

1. Immunogenicity and biodistribution of lipid nanoparticle formulated self-amplifying mRNA vaccines against H5 avian influenza
   Cui et al., Vaccines (2024) - PMID: 39097672
   Product used: PepMix™ Influenza A (HA/Indonesia (H5N1)) 
2. Heightened Epstein-Barr virus immunity and potential cross-reactivities in multiple sclerosis
   Thomas et al., PLoS Pathogens (2024) - PMID: 38843296
   Products used: PepMix EBV (EBNA1) 
3. A vaccine targeting antigen-presenting cells through CD40 induces protective immunity against Nipah disease
   Pastor et al., Cell Reports Medicine (2024) - PMID: 38471503
   Products used: PepMix Nipah Virus (Nucleoprotein N), Nipah virus (Glycoprotein G), Nipah Virus (Fusion Glycoprotein F0) and ECD 

Explore more references on our website. 

PepMix™ for Other Antigens! 

Many different antigens or proteins are available as ready-to-use PepMixes™ for cellular stimulation in functional T cell assays. We offer PepMixes™ related to allergies, neurodegeneration, hemophilia or diabetes, for example: 

• Dust mite allergen 
• Alpha-Synuclein 
• CTFR 
• IGFBP3 
• Arabidopsis antigens 

Selected Publications for PepMix™ Other Antigens: 

1. Der p 5 allergen from house dust mite: first epitope mapping of rabbit IgG blocking antibodies, Lahiani et al., New Microbes New Infections (2019) - PMID: 30622713 Product used: Custom PepMix™ covering Dust Mite Antigen