Immune Monitoring Services

JPT Peptide Technologies offers high-quality immune monitoring services for analyzing antigen-specific immune responses, including T-cell-mediated cellular immunity and antibody-driven humoral responses. Our integrated immunomonitoring platform combines validated immune monitoring assays, high-purity peptide technologies, and regulatory-compliant clinical immune monitoring solutions to comprehensively assess immune function and immune cell activity.

Our innovative peptide-based products and advanced immune cell assays support preclinical research and clinical therapeutic development. Through these services we generate reliable immunomonitoring data for researchers working in oncology, infectious diseases, and vaccine development.

Whether you require cellular immunomonitoring, humoral antibody profiling, or fully regulated clinical immune monitoring services, JPT provides scalable and customized solutions for translational and clinical research programs.

Learn more about immune monitoring here!

Cellular immune monitoring services

Our cellular immune monitoring services enable precise profiling of antigen-specific T-cell responses using validated assays such as ELISpot. These immune cell assays are designed to measure functional immune responses at the single-cell level, providing quantitative and qualitative insights into T-cell-mediated immune function.

Cellular immune responses are primarily mediated by CD4+ and CD8+ T cells that recognize specific peptide antigens and initiate targeted immune reactions. Monitoring these responses is essential for evaluating immune activation, therapeutic efficacy, and vaccine performance.

Our defined peptide products ensure efficient and targeted T-cell stimulation while maintaining high assay performance and data integrity. Our immune monitoring assays enable the measurement of functional T-cell activity, including cytokine secretion, activation status, and antigen-specific response magnitude.

JPT s unique peptide specifications:

Avoid peptide cross-contamination
Inhibit false positive T-cell stimulation by synthetic by-products
Eliminate cell toxic by-products
Allow for peptide stability and peptide solubility evaluation
Learn more about Peptide Quality & Purity

For critical clinical trial monitoring, JPT maintains a dedicated Clinical Grade (CGP) specification that complies with relevant regulatory requirements, including line clearance, quality oversight, and comprehensive batch documentation. The combination of long-standing peptide chemistry expertise, bioinformatics knowledge, and regulated quality standards enables high-quality clinical profiling of cellular immune responses.

Have a look at our cellular immune monitoring services and products:

PepMix Peptide Pools

PepMix peptide pools are widely used in immune monitoring assays to stimulate antigen-specific immune cells. They enable reliable detection and characterization of T-cell responses in assays such as ELISpot, FluoroSpot, intracellular cytokine staining (ICS), and multiparameter flow cytometry.

Our antigen spanning PepMixes are available in a large variety of more than 400 off-the-shelf peptide pools (e.g. SARS-CoV-2, EBV, HCMV, AdV, HPV antigens and many tumor associated antigens) or customized according to the specification of your application and antigens.

Our control pools CEFX and CEF are the gold standard for any antigen-specific cellular assay.

Check our PepMix Peptide Pools list, pricing and information!

Antigen Peptides

Antigen peptides are widely used for efficient immunomonitoring, mapping of T cell epitopes or development of immunotherapies and vaccines.

JPT offers specific peptide epitopes (antigen peptides) for stimulation of T cells in interferon gamma-releasing T cell assays such as ELISPOT, FluoroSpot, intracellular cytokine staining (ICS), and flow cytometry.

Check our Antigen Peptides list, pricing and information!

ELISpot Service

ELISpot (Enzyme-Linked ImmunoSpot) assays are widely used to detect and quantify antigen-specific T-cell responses at the single-cell level. By measuring cytokine secretion, such as interferon-gamma, ELISpot enables sensitive analysis of cellular immune responses and is commonly applied in vaccine research, infectious disease studies, cancer immunotherapy development, and immunomonitoring.

We offer T cell assays such as ELISpot as full service in our dedicated S2 lab. Additionally, we can assist you with target selection, sequence analysis with bioinformatic assistance and with peptide library design. Our service includes peptide synthesis, peptide pooling, matrix pool design & plating and T cell assay execution.

Have a look at our ELISpot Services!

Clinical Peptides & Pools

Clinical peptides and peptide pools are designed for immunomonitoring in clinical research and cell therapy applications. They enable the stimulation and analysis of antigen-specific T-cell responses in patient samples and support standardized immunological assays, such as ELISpot and flow cytometry, in clinical trials.

JPT s Clinical Grade and ISO Plus Peptides & PepMix Pools are produced in production environments regulated by an enhanced quality management system for the more stringent requirements of cell therapy and immunomonitoring. The specification was developed especially to monitor immune cells in clinical trials, bridging the gap between standard RUO peptides and high-prized GMP Peptides. They have been applied in various successful clinical applications.

Please visit Clinical Peptides & Pools!

Humoral immune monitoring services

Our proprietary humoral immune monitoring services allow high resolution profiling of antibody related immune responses. Humoral immune responses are mediated by B cells, which produce antibodies that recognize specific antigens and contribute to immune protection. Monitoring these responses helps evaluate antibody specificity, epitope recognition, and immune dynamics in research and clinical development.

We offer multiple peptide-based solutions with immobilized peptides, such as PepStar Peptide Microarrays, PepSpots Arrays and Peptide ELISA. These platforms support the analysis of purified antibodies, patient sera, and whole blood samples against individual antigens, antigen families, selected epitopes, and neo-epitopes.

Our microarray and peptide array platforms map antibody responses to specific B-cell epitopes in clinical studies, enabling identification of recognition patterns and epitope spreading. Additionally, we can address natural sequence diversity, mutations and post-translational modifications that occur in cancer cells and different types of viruses.

Have a look at our humoral immune monitoring services and products:

PepStar Peptide Microarrays

JPT offers PepStar Peptide Microarrays for profiling patient samples or antibodies, detecting epitopes and neo-epitopes, identifying vaccine targets, and monitoring epitope spreading. These high-resolution microarrays provide reliable and efficient screening tools for applications including therapeutic antibody characterization, novel biomarker discovery, and analysis of protein-protein interactions.

PepStar Peptide Microarrays display overlapping peptide scans across antigens or custom peptide sequences defined by the user. Customers can design the content and layout of fully customized arrays, which are manufactured in our regulated clean-room environment.

Alternatively, you can choose from more than 200 off-the-shelf peptide microarrays featuring overlapping peptide scans across proteins or entire proteomes.

Check our PepStar Peptide Microarrays list, pricing and information!

Antibody Response Profiling Service

Antibody response profiling enables monitoring of antigen-specific antibody responses to better understand humoral immune reactions in research and clinical studies.

Our modular assay service for antibody response profiling, biomarker discovery and serological test development is is a full service using different platforms. The platforms are compatible with antibodies, sera, whole blood and other biological fluids that contain antibodies.

Please visit Antibody Response Profiling!

Peptide ELISA

We offer customized peptide-coated ELISA plates (enzyme-linked immunosorbent assay) for targeted antibody analysis. ELISA is a well-established and highly sensitive immunological method for protein detection; however, the use of peptides requires specialized experimental expertise.

Peptide ELISA supports epitope mapping, identification of protein interaction sites, and serves as a validation assay to confirm results obtained with JPT s peptide microarrays.

Please visit Peptide ELISA!

PepSpots Peptide Arrays on Membrane

JPT s PepSpots are membrane-bound peptide arrays designed for efficient and cost-effective antibody epitope mapping and protein-protein interaction studies. Peptides are synthesized directly onto hydrophilic cellulose membranes using our proprietary SPOT technology, minimizing non-specific binding. Detection is simple and compatible with standard ELISA protocols, enabling rapid screening of multiple peptide sequences.

Please visit PepSpots Peptides on Cellulose!

BioTides Biotinylated Peptides

BioTides are biotinylated peptides designed for biomedical screening assays that require immobilization onto streptavidin-coated beads, membranes, glass slides or microtiter plates (e.g. Peptide ELISA). They are synthesized by JPT's proprietary SPOT synthesis technology, providing fast access to large numbers of biotin peptides at unmatched pricing.

For further information and quote request: visit BioTides!

Neo-epitope immune monitoring services

Cancer neo-antigens are tumor-specific peptide sequences generated by somatic mutations and represent key targets for personalized cancer immunotherapy. However, developing patient-specific therapies requires fast, flexible, and cost-effective immunomonitoring solutions capable of addressing highly individualized peptide sets.

JPT bridges this gap by providing overlapping neo-epitope peptide libraries, pools, and microarrays designed for both cellular and humoral monitoring of immune responses. Our high-throughput peptide synthesis, automated liquid handling, and proprietary microarray technologies enable rapid production of customized peptide formats suitable for large-scale individualized immunotherapy trials.

Explore our dedicated services for Neo-Epitope Immune Monitoring and personalized cancer vaccine development.

Why Choose JPT for Immune Monitoring Services?

Expertise in peptide-based immunology: Decades of experience in peptide synthesis, peptide microarrays and immunological applications supporting both cellular and humoral monitoring studies.
High-throughput screening: Scalable peptide microarray and library-based approaches enable rapid and parallel analysis of immune responses with up to 6900 peptides (in triplicates) simultaneously.
Customizable assay design: Tailored peptide libraries, arrays, and immune monitoring assays designed to fit your specific research needs and target antigens.
Reliable & reproducible data: High-quality peptide synthesis and validated screening platforms ensure accurate and reproducible monitoring of immune function and activity.
High resolution immune profiling: Peptide-based technologies allow precise identification of epitopes and detailed analysis of antigen-specific immune responses at the amino acid level.
Cost-effectiveness: Peptide microarrays and peptide libraries enable efficient and cost-effective large-scale screening of immune responses.
Confidential & expert support: Confidential handling of your project and expert scientific guidance throughout study design, assay development, data interpretation, and follow-up planning.

Planning a project or need more information?

Contact JPT s peptide experts and learn about our exceptional quality and innovative formats for discovery, therapy, and immune monitoring assays. Our customer support provides personalized consultation to define the optimal peptide specifications for your project.

Learn more about our comprehensive Products & Services and advanced Bioassays & Analytics supporting cellular and humoral response profiling.